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Midlife Atherosclerosis and Development of Alzheimer or Vascular Dementia

Objective: To investigate whether midlife atherosclerosis is associated with different dementia subtypes and related underlying pathologies. Methods: Participants comprised the cardiovascular cohort of the Swedish prospective population-based Malmö Diet and Cancer Study (N = 6,103). Carotid plaques and intima media thickness (IMT) were measured at baseline (1991–1994). Dementia incidence until 201

The fragmentation of facts and infrastructural meaning-making : New demands on information literacy

Introduction. This paper presents a theory-driven discussion on the role of facts in society, couched between a brief historical overview and a discussion of the contemporary situation, exemplified in particular by openly available web-based fact services. Implications for the conceptualisation of information literacy – and in particular information literacy in relation to today’s dominant algorit

A numerical study of partitioned fluid-structure interaction applied to a cantilever in incompressible turbulent flow

This study presents an approach for partitioned fluid-structure interaction (FSI) applied to large structural deformations, where an incompressible turbulent solver is combined with a structural solver. The implementation is based upon two different open-source libraries by using MPI as a parallel communication protocol, the packages and OpenFOAM. FSI is achieved through a strongly-coupled scheme.

Confronting the ecology of crisis : The interlinked roles of ecosystem-based adaptation and empowerment

Nature-based solutions (NBS) focus on the material functioning of ecosystems as part of a transformative response to societal challenges. NBS represent a growing response to climate change with a range of interventions emerging across the world to address the causes and effects of climate change. The adoption of NBS is claimed to address a range of Sustainable Development Goals, including empowerm

Prevalens av idrottsrelaterade skador och sjukdomar hos svenska paraidrottare

BAKGRUND: Intresset för parasport har vuxit det senaste årtiondet. Andelen paraidrottare som elitsatsar ökar ochmånga prestationer går att jämföra med idrottare utan funktionsnedsättning. Deltagande i idrott innebär dock en ökadrisk för att drabbas av en idrottsrelaterad skada eller sjukdom (IRSS). IRSS är ett bekymmer inom flertalet idrotter,vilket kan leda till förlorad träningstid samt negativa

Fake news and post-truth in electioneering : Getting past the anger stage

Most of us are fed up of the incessant media coverage of fake news and dishonest political campaigns.We might be fed-up. But at the same time we can’t help but repeatedly mumble our common-sense complaints about a world we don’t recognise: ‘How can even apparently intelligent people believe in fake news about the major issues of this election? Brexit, anti-scientific claims dismissing climate chan

Rural transformation, inequality, and the origins of microfinance

What determines the development of rural financial markets? Starting from a simple theoretical framework, we derive the factors shaping the market entry of rural microfinance institutions across time and space. We provide empirical evidence for these determinants using the expansion of credit cooperatives in the 236 eastern counties of Prussia between 1852 and 1913. This setting is attractive as i

Trade and wage inequality: The mediating roles of occupations in Germany

Recent evidence shows that rising wage inequality in industrialized countries can partially be attributed to trade integration. However, it is unclear what the mechanisms behind this relationship are. Previous explanations pointed towards the displacement of mid-wage manufacturing workers as a response to rising imports. But for Germany it has been shown that rising exports likewise create manufac

Efficacy and safety of inhaled α1-antitrypsin in patients with severe α1-antitrypsin deficiency and frequent exacerbations of COPD

Patients with inherited α1-antitrypsin (AAT) deficiency (ZZ-AATD) and severe chronic obstructive pulmonary disease (COPD) frequently experience exacerbations. We postulated that inhalation of nebulised AAT would be an effective treatment. We randomly assigned 168 patients to receive twice-daily inhalations of 80 mg AAT solution or placebo for 50 weeks. Patients used an electronic diary to capture

Eukaryote hybrid genomes

Interspecific hybridization is the process where closely related species mate and produce offspring with admixed genomes. The genomic revolution has shown that hybridization is common, and that it may represent an important source of novel variation. Although most interspecific hybrids are sterile or less fit than their parents, some may survive and reproduce, enabling the transfer of adaptive var

Data sets, modeling, and decision making in smart cities : A survey

Cities are deploying tens of thousands of sensors and actuators and developing a large array of smart services. The smart services use sophisticatedmodels and decision-making policies supported by Cyber Physical Systems and Internet of Things technologies. The increasing number of sensors collects a large amount of city data across multiple domains. The collected data have great potential value, b