Filtyp
The remains of a wooden stronghold and a fortified manor have been found in Hedemora and Husby parishes in southern Dalecarlia, along with a late medieval city and the northernmost monastery in Sweden. They all stem from the period between about 1350 and 1500. These buildings are the focus of this thesis, which attempts to explore why the architectural expressions from this era are found in these
Bricklaying is one of the most accident-prone professions in the construction industry, with heavy and non-ergonomic lifting being a leading cause of sick leave and back problems. Increased automation is expected to reduce the number of work-related accidents while simultaneously improving productivity. Existing solutions are often expensive and inflexible. This thesis investigates how a pick- and
Sammanfattning Den här studien undersöker tekniska lösningar för bräddmätning inom VA SYDs ledningsnät, med fokus på att förbättra driftssäkerheten vid kritiska bräddpunkter. Genom fältstudier, intervjuer och litteratur har olika sensorteknologier analyserats, där bland annat Siemens SITRANS LR120 har visat sig särskilt lovande. Projektet behandlar hur korrekt konfiguration, kommunikationsval och
Hur kan materialåtgången minskas utan att försämra hållfastheten i betongstrukturer? Det är en tämligen svår fråga men svaret kanske kan hittas med hjälp av spänningsbegränsad strukturoptimering och förspänd betong. Betong är ett av samhällets mest använda byggmaterial och utgör grunden i hus, broar och annan infrastruktur. Materialets stora styrka är dess förmåga att bära trycklaster. När betongConcrete exhibits high compressive strength but limited tensile strength, which restricts its applications where it's structurally efficient with respect to cost, manufacturability and strength. Prestressing is commonly used to counteract tensile stress by introducing compressive forces but the combination of prestressed concrete and optimization is still under development. An important aspect
Chronic obstructive pulmonary disease (COPD) and asthma are heterogeneous respiratory diseases with overlapping symptoms but distinct underlying biology. As both diseases involve dysregulated inflammatory signalling, identifying disease- and compartment-specific pathways and biomarkers could improve diagnosis and treatment. A disintegrin and metalloproteinase 17 (ADAM17) is a key sheddase that inf
Hexavalent chromium (Cr(VI)) is classified as a Group 1 human carcinogen and increases the risk of lung cancer because it can generate reactive oxygen species, induce DNA damage, and trigger epigenetic alterations Occupational Cr(VI) exposure can occur during different work processes, but when this PhD study was initiated, the exposure level to Cr(VI) at Swedish workplaces and its health risk were
How is sustainable development translated in higher education institutions (HEIs)? This study examines how sustainable development has been translated within the ‘policy world’ of HEIs, focusing on one research-intensive university in Sweden. Sustainable development, widely introduced into legislation in 2003, required HEIs to develop policies addressing sustainability. At one faculty at the resea
Background The dura mater has a permeable vasculature similar to that of peripheral organs, and is separated from the brain, which is enclosed within the arachnoid barrier. Fluid and solute transport across the arachnoid barrier between the subarachnoid space (SAS) and dura is crucial for brain waste clearance and immune surveillance, but few neuroimaging approaches can capture this dynamic proces
Bedömning av ett barns talsvårigheter behöver baseras på flera uppgifter och testmetoder för att möjliggöra identifiering av den eller de talproduktionsnivåer som är inblandade. Syftet med studien var att undersöka hur ett benämningstest och ett dynamiskt motoriskt taltest bidrog till observationer av talbeteenden förenliga med brister i talmotorisk planering. Deltagarna var 28 barn mellan tre ochThe assessment of a child’s speech problem should incorporate several tasks and sampling methods to identify the difficulties appointing the speech production level/s involved. This study aimed to investigate how a dynamic motor speech test contributed to a naming test in observing speech characteristics consistent with deficits of speech motor planning. Participants were 28 children, 3 to 9 years
BackgroundIntravenous immunoglobulins (IVIG) have been suggested as an adjunctive treatment in streptococcal toxic shock syndrome (STSS), but there are no conclusive trials. In southern Sweden, IVIG is routinely used in certain hospitals but not in others. We hypothesized that this would resemble a natural experiment, and aimed to evaluate the effect of IVIG in STSS patients.MethodWe conducted a p
Carbon sequestration in arable soils is gaining increasing attention in global policymaking initiatives for climate-change mitigation. Large-scale assessments of soil organic carbon development in arable land are affected by the scarcity of reliable time series of soil organic carbon monitoring data and often fail to replicate observed trends or appreciate any effects induced by changes in soil ma
Vi möter dagligen larmrapporter om att den regelbaserade världsordning som etablerades efter andra världskriget håller på att bryta samman. För den som vill få en förklaring till varför detta händer och en hum om vart världen är på väg finns en färsk analys att tillgå i Eswar Prasads The Doom Loop, i svensk översättning ungefär ”domedagsspiralen”.
The study investigates how the Best Interests of the Child principle in the UN Children's Rights Convention (Article 3) has been adapted in custody disputes in Egypt, Sweden, and Uzbekistan. Although the Convention on the Rights of the Child offers a common normative benchmark, divergent legal cultures shape its domestic meaning: Egypt is governed by religious and state legal norms intersecting wi
Patients with pulmonary arterial hypertension (PAH) experience long diagnostic delays, high functional class at diagnosis and poor prognosis. We aimed to study the differentiative and predictive value of 90 inflammatory and immunomodulatory related proteins in idiopathic and hereditary PAH (IPAH/HPAH) and systemic sclerosis-associated PAH (SSc-APAH). Cohort 1 comprised patients with SSc-APAH ( n =
Naturbetesmarker och slåtterängar är bland de mest artrika miljöerna i det svenska jordbrukslandskapet och har därför en avgörande betydelse för bevarandet av biologisk mångfald. För att uppfylla kraven i EU:s Naturrestaureringsförordning och de nationella miljökvalitetsmålen krävs att Sverige både bevarar befintliga gräsmarker med höga naturvärden och restaurerar betydande arealer så att de erhål
ObjectivesPeople with serious illness approaching end of life often end up in emergency and hospital care, frequently against expressed preferences. Consequently, oncology trials record care days as a measure of treatment burden called “time toxicity.” However, this measure ignores the diminishing marginal utility of time: that the value of a day is higher when fewer remain. We aimed to incorporat
