Longitudinal amyloid and tau PET imaging in Alzheimer's disease : A systematic review of methodologies and factors affecting quantification
Deposition of amyloid and tau pathology can be quantified in vivo using positron emission tomography (PET). Accurate longitudinal measurements of accumulation from these images are critical for characterizing the start and spread of the disease. However, these measurements are challenging; precision and accuracy can be affected substantially by various sources of errors and variability. This revie