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The Mesoproterozoic in the Nordic countries

During the Mesoproterozoic, central Fennoscandia and Laurentia (Greenland) were characterized by a weakly extensional stress regime, as evident from episodic rapakivi granites, dolerite dykes, continental rift intrusives, sandstone basins and continental flood basalts. Along the southwestern active margin of Fennoscandia, the 1.64-1.52 Ga Gothian and 1.52-1.48 Ga Tele-markian accretionary events r

Association of Insulin Resistance, Arterial Stiffness and Telomere Length in Adults Free of Cardiovascular Diseases.

Chronic inflammation and oxidative stress might be considered the key mechanisms of aging. Insulin resistance (IR) is a phenomenon related to inflammatory and oxidative stress. We tested the hypothesis that IR may be associated with cellular senescence, as measured by leukocyte telomere length (LTL), and arterial stiffness (core feature of arterial aging), as measured by carotid-femoral pulse wave

Aeration control - a review

This review covers automatic control of continuous aeration systems in municipal wastewater treatment plants. The review focuses on published research in the 21st century and describes research into various methods to decide and control the dissolved oxygen (DO) concentration and to control the aerobic volume with special focus on plants with nitrogen removal. Important aspects of control system i

A comparative study of elevation data from different sources for mapping the coastal inlets and their catchment boundaries

Mapping coastal inlets and their catchment areas is essential for management of the coastal zone. The coastal inlets are important channels of exchange of nutrients, water and sediment between the land and sea. They are also important elements of the coastal hydrological system and play a vital role in controlling the water flow into the sea during floods. Blocking of the coastal inlets is one of

The global audit profession and the international financial architecture: Understanding regulatory relationships at a time of financial crisis

This paper explores how regulatory relationships in the global audit arena are being affected by the current financial crisis. Key policy initiatives and debates are analyzed, along with Institutional interactions, in particular between the International Federation of Accountants (IFAC), international regulators and the large audit firms. The events are placed in the context of the new internation

Tasquinimod Modulates Suppressive Myeloid Cells and Enhances Cancer Immunotherapies in Murine Models

A major barrier for cancer immunotherapy is the presence of suppressive cell populations in patients with cancer, such as myeloid-derived suppressor cells (MDSC) and tumor-associated macrophages (TAM), which contribute to the immunosuppressive microenvironment that promotes tumor growth and metastasis. Tasquinimod is a novel antitumor agent that is currently at an advanced stage of clinical develo

Geometric model for metalorganic vapour phase epitaxy of dense nanowire arrays

We propose a geometric model to estimate the contribution of substrate surface diffusion to growth of dense nanowire arrays using metalorganic vapour phase epitaxy. It is shown that the nanowire mantle area becomes the most significant collector of growth material when the nanowire diameter is large and the inter-nanowire pitch is small. It is concluded that this growth regime is important for the

Artificial recharge by floodwater spreading estimated by water balances and groundwater modelling in arid Iran

Water harvesting and artificial recharge have been a traditional solution to water scarcity problems in the arid and semi-arid Middle East for thousands of years. These techniques are increasingly being encouraged, and recently there has been renewed interest to find improved methods for water harvesting and artificial recharge in many arid countries. In this study, water balance calculations and

Robust distributed routing in dynamical networks -- Part I: Locally responsive policies and weak resilience

Abstract in UndeterminedRobustness of distributed routing policies is studied for dynamical networks, with respect to adversarial disturbances that reduce the link flow capacities. A dynamical network is modeled as a system of ordinary differential equations derived from mass conservation laws on a directed acyclic graph with a single origin-destination pair and a constant total outflow at the ori

The Functionality of Conceptual Terms in International Law and International Legal Discourse

Investigating the meaning of conceptual terms is an important task for international legal scholars. Traditionally, the meaning of conceptual terms has been analyzed by reference to what those terms describe, namely a relationship between, on the one hand, the particular properties identifying a particular phenomenon or state of affairs as belonging to the extension of a concept, and on the other

Våldet och kärleken : Våldsutsatta kvinnors begripliggörande av sina erfarenheter

The purpose of the thesis is to study, through the narratives of women subjected to violence, how men’s violence against women in intimate relationships is accounted for, and how such accounts vary with the type of social relation and context she is in. The specific context in focus here is the legal system, with the police as the first link in the legal chain. The empirical material consists of

Novel approaches to explore mechanisms of epileptic seizures - optogenetic and chemogenetic manipulation of hippocampal circuitry

Epilepsy comprises a family of neurological disorders characterized by recurrent seizures, which can be highly debilitating. Up to 30% of patients with temporal lobe epilepsy, the most common form of the disorder in adults, arising in the hippocampus, cannot be effectively treated by current pharmaceuticals. Novel treatment strategies are highly needed, as well as increased understanding of the hi

Photon-hadron jet correlations in p plus p and Au plus Au collisions at s(NN)=200 GeV

We report the observation at the Relativistic Heavy Ion Collider of suppression of back-to-back correlations in the direct photon+jet channel in Au+Au relative to p+p collisions. Two-particle correlations of direct photon triggers with associated hadrons are obtained by statistical subtraction of the decay photon-hadron (gamma-h) background. The initial momentum of the away-side parton is tightly

Long-term exposure to air pollution and hospital admissions for ischemic stroke. A register-based case-control study using modelled NOx as exposure proxy

Background: Long-term exposure to air pollution is a hypothesized risk factor for ischemic stroke. In a large case-control study with a complete study base, we investigated whether hospital admissions for ischemic stroke were associated with residential concentrations of outdoor NOx, as a proxy for exposure to air pollution, in the region of Scania, Southern Sweden. Methods: We used a two-phase ca

Cell coupling in mouse pancreatic beta-cells measured in intact islets of Langerhans

The perforated whole-cell configuration of the patch-clamp technique was applied to functionally identified beta-cells in intact mouse pancreatic islets to study the extent of cell coupling between adjacent beta-cells. Using a combination of current- and voltage-clamp recordings, the total gap junctional conductance between beta-cells in an islet was estimated to be 1.22 nS. The analysis of the cu

Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

OBJECTIVE-Common variants in FTO (the fat mass- and obesity-associated gene) associate with obesity and type 2 diabetes. The regulation and biological function of FTO mRNA expression in target tissue is unknown. We investigated the genetic and nongenetic regulation of FTO mRNA in skeletal muscle and adipose tissue and their influence on in vivo glucose and fat metabolism. RESEARCH DESIGN AND METHO