Filtyp
Background: Degraded extracellular matrix can stimulate the innate immune system via the Toll-Like Receptor-4 (TLR4). In the pancreas, syndecan-anchored heparan sulphate (HS) on the ductal epithelium can be cleaved off its protein cores by the proteases (trypsin and elastase) and potentially activate TLR4 signalling. Methods: To investigate this signalling event, a low sulphated HS (500 mu g/ml) w
Zinc oxide nanorod-extended gate field effect transistor (MOSFET) is demonstrated for the detection of calcium (Ca2+) ions. ZnO nanorods were grown on the surface of a silver wire to produce an electrochemical nanosensor for selectively detecting Ca2+. The electrochemical response from the interaction between the ZnO nanorods and Ca2+ in an aqueous solution is coupled directly to the gate of a fie
This study investigates the effects that public sector reforms had in the cultural field in European countries over the past two decades. The study highlights changing conditions for public/nonprofit management due to governance and public sector reforms. It does so by applying a multidisciplinary literature survey methodology, which is rare in management studies. The literature survey identifies
This paper combines an atmospheric transport model and a terrestrial ecosystem model to estimate gross primary productivity (GPP) and net ecosystem productivity (NEP) of the land biosphere. Using atmospheric CO2 observations in a Carbon Cycle Data Assimilation System (CCDAS) we estimate a terrestrial global GPP of 146 +/- 19 GtC/yr. However, the current observing network cannot distinguish this be
Populärvetenskaplig artikel om kemisten och nobelpristagaren Fritz Haber, som arbetade med att ta fram stridsgas före och under första världskriget.
Brachyradia, new genus, is proposed and described for two new species of the tribe Exechiini (Diptera: Mycetophilidae) from the Oriental and Australasian regions. The type species, Brachyradia asianca, new species, is described from Thailand, Malaysia, and Indonesia (Sulawesi), and a second species, Brachyradia australis, new species, from Indonesia (Sulawesi) and Papua New Guinea. The systematic
The enzyme myeloperoxidase shows several unusual properties compared to other peroxidases, e.g. a red-shifted absorption spectrum and a peroxidase activity towards chloride. It has been suggested that this is caused by the unusual covalent links between the heme group and the surrounding protein, but whether it is caused by the two ester links to Glu-242 and Asp-94 or the sulfonium ion linkage to
The aim of this was to determine whether the change of size observed at the first response evaluation after initiation of first-line combination chemotherapy correlates with overall survival (OS) in patients with metastatic breast cancer (MBC). The change in size of tumors derived from measurements according to Response Evaluation Criteria In Solid Tumors (RECIST) at the first evaluation on comput
This paper analyses global climate politics from the 2007 Bali Roadmap over the 2009 breakdown at COP15 to the following COP meetings with a focus on central issues and tendencies. The analysis is structured by applying the concepts of content and process as empirical and heuristic tools. This is used as the point of departure to analyse the road to Paris, where COP21 is held in 2015 with the stat
This paper examines the importance of influent fractionation, kinetic, stoichiometric and mass transfer parameter uncertainties when modeling biogas production in wastewater treatment plants. The anaerobic digestion model no. 1 implemented in the plant-wide context provided by the benchmark simulation model no. 2 is used to quantify the generation of CH4, H-2 and CO2. A comprehensive global sensit
Adaptive radiations have long served as living libraries to study the build-up of species richness; however, they do not provide good models for radiations that exhibit negligible adaptive disparity. Here, we review work on damselflies to argue that nonadaptive mechanisms were predominant in the radiation of this group and have driven species divergence through sexual selection arising from male-f
Denna rapport är en redovisning av arbete utfört inom projektet "Kyrkomusikaliskt nätverk" vilket varit ett delprojekt inom det övergripande projektet "Nordkalottens universitet".
Data on net CO2 exchange from eight forests in Denmark, Sweden, Finland and Iceland were used to analyse which factors were controlling photosynthesis and respiration. The forests consisted of different species ranging in climatic condition from temperate to subarctic. Only well mixed conditions were analysed (u* > 0.3 m s(-1)). The parameters of a light response function showed strong seasonal va
Conclusion: The study showed the value of using intravital microscopy (IVM) analysis for the study of neoangiogenesis. It demonstrated that the model and the analytical methodology could be used to evaluate in detail the effects of treatment strategies for solid tumours. Objectives: Neoangiogenesis is a key component of tumour progression, invasion and metastasis. In clinical trials monoclonal ant
Bone scintigraphy is usually obtained as a whole-body scan producing 2 images: an anterior view and a posterior view. Sometimes abnormal findings in the spine are difficult to distinguish on whole-body bone scans. SPECT/CT may be performed to localize and interpret a lesion correctly and to help differentiate between benign and metastatic lesions. The assessment of whether SPECT/CT is needed is us
Global food production is identified as a great threat to the environment. In combination with technical advances in agriculture, dietary change is suggested to be necessary to reduce the environmental impact of the food system. In this article a systematic review assessing the environmental impact of dietary change is performed. The aims are to i) evaluate the scientific basis of dietary scenario
Background: During the last decades, global migration has increased and many immigrant groups have a higher prevalence than the native born population of several cardiovascular disease risk factors, including poor dietary habits. However, it is uncertain if dietary habits in immigrant populations reflect dietary habits in their country of origin or if the current diet is a consequence of the migra
