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Delade meningar : Retorisk flertydighet och den pluralistiska publiken i politiska förnyelseprocesser.

Denna avhandling undersöker retorisk flertydighet som en egenskap hos uttryck som adresserar sammansatta, heterogena publiker. Avhandlingens syfte är att utveckla konceptuella verktyg för analysen av flertydiga kommunikativa handlingar, för att undersöka vilka utfall de kan möjliggöra. Avhandlingens utgångspunkt är att uttryck är meningsfulla och fundamentalt sociala handlingar, som alltid är en dThis thesis is an inquiry into rhetorical ambiguity as a property of utterances addressing composite, heterogeneous audiences. The purpose is to develop conceptual tools to analyse ambiguous communicative acts for the outcomes they make possible. The thesis proceeds from the assumption that utterances are purposeful and fundamentally social acts, always part of an ongoing social dialogue. As such,

PDZD8 is not the 'functional ortholog' of Mmm1, it is a paralog

Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells. However, identifying PDZD8 as a "functional ortholog" of yeast Mmm1 (maintenance of mitochondrial morphology protein 1) is at odds with the phylogenetic data. PDZD8 and Mmm1 are paralogs, not orthologs, whic

The lived experience of Huntington’s disease : A phenomenological perspective on genes, the body and the lived experience of a genetic disease

The purpose of this article is to explore the intersections between genes, the body and the lived experience of a genetic disease. This article is based on empirical material from a study on how individuals affected by Huntington’s disease experience their everyday life. This study identified two themes that represent and capture the experience of the affected individuals. The themes are (1) notic

Proportionalitetsprincipen i 2017 års förvaltningslag

Artikeln handlar om vad den nu lagfästa proportionalitetsprincipen i den nya förvaltningslagen innebär. I artikeln beskrivs mot bakgrund av tidigare forskning hur principen, med ursprung i tysk förvaltningsrätt, har fått insteg i svensk lagstiftning och utvecklats genom praxis, delvis med hjälp av europarätten. Vidare undersöks i vilken mån den nya regleringen uppfyller lagstiftningens syfte att f

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis

The linear ubiquitin chain assembly complex (LUBAC) is required for optimal gene activation and prevention of cell death upon activation of immune receptors, including TNFR1 1 . Deficiency in the LUBAC components SHARPIN or HOIP in mice results in severe inflammation in adulthood or embryonic lethality, respectively, owing to deregulation of TNFR1-mediated cell death 2-8 . In humans, deficiency in

Julia sets of orthogonal polynomials

For a probability measure with compact and non-polar support in the complex plane we relate dynamical properties of the associated sequence of orthogonal polynomials {P n } to properties of the support. More precisely we relate the Julia set of P n to the outer boundary of the support, the filled Julia set to the polynomial convex hull K of the support, and the Green’s function associated with P n

‘I laid the foundation stone to this house’ : Aristocratic messages in Glimmingehus castle, Scania

The purpose of this paper is to discuss decorated stone tablets with coats of arms and memorial texts found on castle walls. The example considered here is Glimmingehus in Scania, in southern Sweden, erected in the late 15th century. Tablets with texts, coat of arms and ornaments are to be found both outside and inside the castle. The messages on the tablets can be said to promote a world of an el

Test-specific differences in verbal memory assessments used prior to surgery in temporal lobe epilepsy

OBJECTIVE: To study the relationship between two commonly used verbal memory tests in presurgical evaluation for temporal lobe epilepsy (TLE) in Sweden, the Claeson-Dahl Test for verbal learning and retention (CDT) and the Swedish version of the Rey Auditory Verbal Learning Test (RAVLT).METHODS: Fifty-nine patients with TLE (male: 41%, mean: age 41.7 ± 12.3 years; epilepsy onset at mean age: 18.3

How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis : analysis of 10,500 patients (Sjögren Big Data Project)

OBJECTIVES: To evaluate the influence of the main immunological markers on the disease phenotype at diagnosis in a large international cohort of patients with primary Sjögren's syndrome (SjS).METHODS: The Big Data Sjögren Project Consortium is an international, multicentre registry created in 2014. As a first step, baseline clinical information from leading centres on clinical research in SjS of t

Self-Reported Needs for Care, Support and Treatment of Persons Who Frequently Visit Psychiatric Emergency Rooms in Sweden

Aim: To investigate self-reported needs for care, support and treatment among persons who frequently visit psychiatric emergency rooms (PERs).Design: A cross-sectional design. Qualitative and quantitative data were collected using an interview-based manual. Qualitative data were analysed using content analysis, whereas quantitative data were analysed using descriptive, non-parametric statistical t

Elites and the expansion of education in nineteenth-century Sweden

A large literature emphasizes that elite capture of political institutions hampered the spread of mass schooling in the nineteenth and twentieth century. We collect new data on investments in elementary education and the distribution of voting rights for more than 2,000 local governments in nineteenth‐century Sweden and document that educational expenditure was higher where the distribution of pol