Brain-machine interfaces (BMIs) provide a uni- or bidirectional communication link between the central nervous system and the outside world. This link facilitates the studying of neuronal mechanisms underlying behavior as well as the treatment of neurological disease. Wired BMIs are limited in the sense that they restrict the mobility of the subject and they increase the risks for post-surgical co

The Coastal Giant Salamander (Dicamptodon tenebrosus) is classified as threatened at the northern periphery of its range in British Columbia (BC), Canada, primarily due to forestry practices and habitat fragmentation. Characterising dispersal behaviour and population connectivity is therefore a priority for this region, while genetic differentiation in core versus peripheral locations remains unst

The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 in STXBP4/COX11, and rs10941679 at 5p12, and reanalyzed the previous associations using additional ca

A novel method of the recovery of a dietary fibre containing material from olive mill wastewater (OMW) was developed. Extraction was based on thermal treatment with mixtures of ethanol and acids, prior to the isolation of the alcohol insoluble residue (AIR). Different mixtures were tested and the extracted residues were characterized. The maximum AIR recovery accounted 64.8 g/100 g OMW dry matter,

Improving our knowledge of drivers’ behaviour, especially in hazardous situations is a key to understanding why accidents occur and how to improve safety on our roads. Crash surrogate measures have proven to be very useful in traffic safety analysis. As a valid crash surrogate measure shares the same logical chain of events as actual crashes, studying those events increases the opportunities to an

A hip fracture is probably one of the most fatal fractures for the elderly and estimated worldwide to reach 5 million cases annually by the year 2050. Thus, continuing efforts in preventing fractures, with more research and improved treatment strategies for those who do fracture, seem crucial. The primary aims of this thesis, which comprises seven original papers, including a total of 656 patients

A method was developed based on supercritical fluid chromatography for quantitative determination of carotenoids in extracts of Scenedesmus sp. By utilizing the low backpressure in supercritical fluid chromatography, a C18 column and a 2-ethyl pyridine column were coupled in series. It was concluded that even minor changes in temperature had a substantial effect on selectivity. A standard mixture

Background/Aims: To investigate whether a daily intake of a nutrient-balanced ready meal containing 4 g of oat beta-glucans lowers total cholesterol (T-C) and low-density-lipoprotein cholesterol (LDL-C) in hyperlipidemic subjects and to evaluate its effect on postprandial glucose and insulin concentrations. Methods: A parallel, placebo-controlled trial was carried out in 43 healthy men and women w

As reflected in elevated rates of sexually transmitted infections, there is a high prevalence of risky sexual behavior among Ugandan university students. It has been assumed that alcohol contributes to risky sexual behavior. However, perhaps owing to methodological issues, this relationship has found only mixed support in empirical research. The present study analyzes the association between alcoh

Migrating birds are believed to minimize the time spent on migration rather than energy. Birds seem to maximize migration speed in different ways as a noteworthy variation in migration strategies exists. We studied migration strategies of a flight mode and feeding generalist, the Lesser Black-backed Gull Larus fuscus, using GPS-based satellite telemetry. We expected the gulls to achieve very high

The overall aim of this thesis was to describe parent’s experiences, reactions and needs in connection with a routine ultrasound examination during pregnancy when the foetus was found to have an abnormal ultrasound finding. The data collection began in February 2005 and the one year cohort study was completed by March 2006. The participants in this study were each asked if they would also consid

We hypothesised that the correlation between autoantibody specificity for the ZnT8 Arg325Trp isoforms and the type 2 diabetes-associated rs13266634 may affect beta-cell function at type 1 diabetes (T ID) onset. To study this, we tested 482 newly diagnosed diabetic probands and 478 healthy siblings from the Danish population-based T1D registry for autoantibodies to ZnT8 (ZnT8A) in addition to GAD65

The shortage of He-3 isotope to be used as optimum neutron absorber in various neutron detection applications is considered. Here we present some general requirements in different applications to introduce more specialized papers which describe recent progresses. Considering that the neutron detection is important in a very wide range of applications we cannot be exhaustive but we describe the mos

The near monolayer depth resolution of medium energy ion scattering is utilized to develop a probe of the depth dependent composition of bimetallic nanoparticles supported on planar oxide supports. The approach fits spectra of scattered ion intensity versus ion energy at well-defined scattering angles taking into account the asymmetric line shape in such spectra and also the depth dependent loss p

Rubber covered cylinders in rolling contact are studied in two cases; rolling over a flat surface and rolling over a groove. In the first case, two different finite element procedures are compared for the purpose of investigating if computational savings can be made when taking amplitude dependent effects into account by using a modified viscoelastic steady state rolling procedure. This procedure

Multimorbidity, according to the World Health Organization, exists when there are two or more chronic conditions in one patient. This definition seems inaccurate for the holistic approach to Family Medicine (FM) and long-term care. To avoid this pitfall the European General Practitioners Research Network (EGPRN) designed a comprehensive definition of multimorbidity using a systematic literature re

Popular Abstract in Swedish Cancer är den vanligaste dödsorsaken bland barn mellan 1–14 år i Sverige. Neuroblastom, som nästan uteslutande drabbar barn, är en aggressiv cancersjukdom som har sitt ursprung i det sympatiska (icke-viljestyrda) nervsystemet. I frisk vävnad råder strikt balans mellan celldelning och celldöd, medan cancerceller kännetecknas av en ohämmad celldelning och minskad celldödNeuroblastoma is a childhood tumor of the developing sympathetic nervous system (SNS) and is the most commonly diagnosed form of cancer in children before one year of age. Although survival curves have improved for these patients during the past decades, the conventional regimen of neuroblastoma treatment has clearly reached a plateau of efficiency with regard to increasing the survival rates of h