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Telavancin is a novel bactericidal lipoglycopeptide with multiple mechanisms of action against gram-positive pathogens. The aim of this study was to describe the dynamics of the antimicrobial effect of telavancin against two strains of Staphylococcus aureus (methicillin susceptible and methicillin resistant) in an in vitro kinetic model with simulated human pharmacokinetics. Also, static experimen
In cooperative breeding systems driven by kin selection, effective kin-recognition cues are important. Recognition could be achieved by the direct assessment of the genetic relatedness of individuals or by learning through association. In the Seychelles warbler, Acrocephalus sechellensis, female subordinates maximize indirect fitness by preferentially helping genetically related nestlings. Help se
Popular Abstract in Swedish Boken handlar om hur fotojournalistiken som redaktionellt koncept introducerades i Sverige. Det är främst bildtidningen Se som studeras och det under dess första åtta år, dvs. 1938-1945.This dissertation describes and analyses the way that Se reported on the world between 1938—1945. Comparative analysis is the most important technique to describe Se’s type of journalism. Se is compared to the American picture magazine Life, the British picture magazine Picture Post, and the Swedish edition of the German pictorial Signal. Se is also compared with its Swedish competitors, for examp
Biodiversity patterns of vascular plant species were studied along altitudinal gradients in the Faroe Islands. Plants were sampled from five different mountains (150-856 m a.s.l.) at 50 m altitudinal intervals. Included in the study were 107 vascular plant species. In order to compare only altitudes with the same number of plots, three different analyses were carried out. One analysis included fiv
Denna rapport ger en översikt över kulturgeografisk forskning som berör kulturmiljöer i de tre svenska storstadsregionerna under efterkrigstiden. Översikten är strukturerad efter tema snarare än tidsavsnitt eller region. Dessa tema är "Mark och planering", "Stadens funktionsuppdelning och dagligrum", "Geografisk stadsekologi", "Platsen i staden" samt "Segregation och stadsomvandling". Rapporten ha
This paper explores the role of distant knowledge links and policy actions for the development of biotechnology clusters. It seeks to challenge the prevailing view that the birth and early development of high technology industries are always spontaneous phenomena which are mainly based on local knowledge. Departing from the theoretical concept of regional innovation systems (RIS), a distinction be
Postoperative thromboembolic events are a major cost factor for every healthcare system. Although thromboprophylaxis carries its own costs, the application of a thromboprophylactic regimen is cost-effective in most instances, at least in high-risk patients. A regimen of general postoperative prevention of deep vein thrombosis is always more cost-effective than surveillance programmes with treatmen
While there is growing awareness of the importance of gender issues in medicine, with new knowledge and new perspectives inmedical curricula are scarce. In 1996, the Medical Faculty of Goteborg University, Sweden, determined that a gender-issues perspective be included in medical education. In 1999, course organizers from preclinical and clinical departments of the faculty were interviewed to dete
BACKGROUND: A standardised suction technique has been used to sample plasma proteins in dermal interstitial fluid (IF) serially for 5 to 6 days from a suction-induced skin mini-erosion. Increased protein concentrations ascribed to inflammation have been shown from day 1 onward. In this study, we assessed the effect of two different extraction pressures on IF sample composition. METHODS: Total prot
Boundary finding in simulated medical images is performed by optimizing the Fourier coefficients in a parametric surface representation with respect to an objective function. The deformable model is fitted to the data using the brightness gradient component which is normal to the surface. A low order (<10) Fourier series expansion offers a sufficiently accurate representation for many inherently s
Objective: To evaluate under- and overreporting and their determinants in the EPIC :24-hour diet recall (24-HDR) measurements collected in the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: Cross-sectional analysis. 24-HDR measurements were obtained by means of a standardised computerised interview program (EPIC-SOFT). The ratio of reported energy intake (EI) to estim
En undersökning av hur romaner har använts i högskoleutbildning (svenska och litteraturvetenskap), med exemplet Växjö högskola/universitet, under åren 1971-2003. Scheman, litteraturlistor och kursplaner står i fokus för analyserna.
[1] Methane fluxes were measured at five sites representing oligotrophic peatlands along a European transect. Five study plots were subjected to elevated CO2 concentration (560 ppm), and five plots to NH4NO3 (3 or 5 g N yr(-1)). The CH4 emissions from the control plots correlated in most cases with the soil temperatures. The depth of the water table, the pH, and the DOC, N and SO4 concentrations w
Oxidative stress has been ascribed a role in the pathogenesis of diabetes and its complications, and stress proteins have been shown to protect organisms in vitro and in vivo against oxidative stress. To study the putative role of one of the most abundant cytoprotective stress proteins, inducible cytoplasmic 72-kDa-mass heat shock protein (Hsp-72), in the pathogenesis of diabetes, we measured its
