The mechanistic implications of the kinetic behaviour of a fusion protein of mitochondrial malate dehydrogenase and citrate synthase have been reanalysed in view of predictions based on experimentally determined kinetic parameter values for the dehydrogenase and synthase activities of the protein. The results show that the time-course of citrate formation from malate in the coupled reaction cataly

In flowering plants, the onset and duration of female receptivity vary among species. In several species the receptive structures wilt upon pollination. Here we explore the hypothesis that postpollination wilting may be influenced by pollen and serve as a general means to secure paternity of the pollen donor at the expense of female fitness. Taking a game-theoretical approach, we examine the poten

In a road simulator study, a significant source of sub-micrometer fine particles produced by the road-tire interface was observed. Since the particle size distribution and source strength is dependent on the type of tire used, it is likely that these particles largely originate from the tires, and not the road pavement. The particles consisted most likely of mineral oils from the softening filler

The purposes of this study were: (i) to determine the test-retest reliability of isokinetic ankle dorsiflexor strength measurements in young healthy adults using the Biodex dynamometer, and (ii) to examine several statistical measures for the interpretation of reliability. Thirty men and women (mean age 23 +/- 3 years) performed three maximal concentric contractions at 30 degrees/s, 60 degrees/s,

Popular Abstract in Swedish Kardiovaskulär sjukdom karaktäriseras av lipid accumulering och inflammation i artärerna. Sjukdomen startar tidigt med att monocyter vandrar ut i kärlväggen där de differentierar till makrofager, tar upp modifierade lipoproteiner och utvecklas till skumceller. En samtidig inflammation bidrar till att fler celler och mer lipider ansamlas och ett aterosklerotiskt plack böCardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. A simultaneous inflammatory response further enhances lipid and cell accumulation at sites of lesion development, resulting in progression of at

Gliomas are among the most aggressive malignant tumors and the most refractory to therapy, in part due to the propensity for malignant cells to disseminate diffusely throughout the brain. Here, we have used 27 K cDNA microarrays to investigate global gene expression changes between normal brain and high-grade glioma (glioblastoma multiforme) to try and better understand gliomagenesis and to identi

Byggd miljö knyts med tiden ofta till olika mer eller mindre specifika betydelser. Vill vi förändra staden måste vi också förhålla oss till de livsmönster och det bruk som uppstått inom ramen för den gamla bebyggelsen, oavsett om vi vill bygga nytt vid sidan av eller förändra det gamla i grunden. Denna artikel avser belysa något kring hur vi kan undersöka en sådan lokal etablering av betydelser oc

Treatment with adrenocorticotrophic hormone (ACTH) has a well-documented cholesterol-lowering effect. Increased uptake of low-density lipoprotein (LDL) by HepG2 cells in response to incubation with ACTH has been demonstrated but the precise cholesterol-lowering mechanism has resisted elucidation. Since apolipoproteins are important determinants of lipoprotein metabolism, we sought to extend the kn

Expression of genes for respiratory chain dehydrogenases was investigated in potato (Solanum tuberosum L. cv. Desiree) leaves. The recently characterized nda1 and ndb1 genes, homologues to genes encoding the non-proton pumping respiratory chain NADH-dehydrogenases of Escherichia coli and yeast, were compared to genes encoding catalytic subunits of the proton-pumping NADH dehydrogenase (complex I).

We describe the epidemiology of all distal radial fractures in young adults (men 20-59 years, women 20-49 years) in Lund (1992-95) and Malmo (1994-95), Sweden. During the study period, there were 341 patients with 346 fractures in the two cities, found through the Hospital Register of Diagnoses in Lund and the register of the Radiology Department in Malmo. More than half of the fractures were disl

Abstract is not available

Three previously unknown high-energy gamma-ray transitions between 4.2 and 5.4 MeV were identified in the T-z=-1/2 nucleus Fe-51 following the fusion-evaporation reaction S-32(Si-28, 2alpha1n)Fe-51. These transitions represent decays of core excited states. The gamma rays were detected in the Ge detector array Gammasphere combined with the neutron detector system Neutron Shell and the charged-part