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Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF.

Caveolae are invaginations in the plasma membrane that depend on caveolins and cavins for maturation. Here, we investigated the pulmonary phenotype in mice lacking cavin-1. Bright field and electron-microscopy showed that the cavin-1-deficient mice lacked caveolae in the lung, had an increased lung tissue density, and exhibited hypertrophic remodeling of pulmonary arteries. The right ventricle of

Intense and widespread seismicity during the end-Triassic mass extinction due to emplacement of a large igneous province

Multiple levels of earthquake-induced soft-sediment deformations (seismites) are concentrated in the end-Triassic mass extinction interval across Europe. The repetitive nature of the seismites rules out an origin by an extraterrestrial impact. Instead, this intense seismic activity is linked to the formation of the Central Atlantic magmatic province (CAMP). By the earliest Jurassic the seismic act

Optimal combination of form and motion cues in human heading perception

We examined what role motion-streak-like form information plays in heading perception. We presented observers with an integrated form and motion display in which random-dot pairs in a 3D cloud were oriented toward one direction on the screen (the form FOE) to form a radial Glass pattern while moving in a different direction in depth (the motion FOE). Observers' heading judgments were strongly bias

Characterization of olfactory sensory neurons in the white clover seed weevil, Apion fulvipes (Coleoptera: Apionidae).

Seed-eating Apion weevils (Coleoptera: Apionidae) cause large economic losses in white and red clover seed production across Europe. Monitoring and control of clover weevils would be facilitated by semiochemical-based methods. Until now, however, nothing was known about physiological or behavioral responses to semiochemicals in this insect group. Here we analyzed the antenna of the white clover (T

Four-wave-mixing spectroscopy of peridinin in solution and in the peridinin-chlorophyll-a protein

A model for the third order optical response of carotenoids is used to analyse transient grating and pump-probe data of peridinin in solution and bound in the peridinin-chlorophyll protein (PCP). For peridinin in solution, the transient grating signal detected at 505 nm exhibits a bi-exponential recovery whose fast phase is assigned to relaxation from the S-2 state that has a lifetime of 75 +/- 25

Livsmedelsprotesterna i Malmö 1799

This is at study of a food riot that took place in the southern Swedish city of Malmö in 1799. It demonstrates that E P Thompon’s influential concept of a “moral economy” still is a quite productive analytical tool. Focusing on the relation between the crowd and the authorities, the essay demonstrates that a moral economy was partly shared by the two groups, but clashed with the new ideology of fr

Search for WZ resonances in the fully leptonic channel using pp collisions at root s=8 TeV with the ATLAS detector

A search for resonant WZ production in the l nu l'l' (l, l' = e, mu) decay channel using 20.3 fb(-1) of root s = 8 TeV pp collision data collected by the ATLAS experiment at LHC is presented. No significant deviation from the Standard Model prediction is observed and upper limits on the production cross sections of WZ resonances from an extended gauge model W' and from a simplified model of heavy

Five-region study finds no evidence of undiagnosed type 2 diabetes in Swedish 11- to 13-year-olds

AimChildhood obesity is now an established public health problem in most developed countries, and there is concern about a parallel increase of type 2 diabetes. The aim of this study was to estimate the prevalence of undiagnosed type 2 diabetes in overweight Swedish school children from 11 to 13years of age. MethodsBody mass index (BMI) was measured in 5528 schoolchildren in the 6th grade, from 11

Remnants of arc-related Mesoarchaean oceanic crust in the Tartoq Group of SW Greenland

The Tartoq Group, located in SW Greenland, consists of supracrustal rocks of mainly tholeiitic basaltic composition, including pillow lavas, sills/dykes and gabbros, as well as ultramafic rocks. Metamorphic grade ranges from greenschist fades to granulite facies. The Tartoq Group crops out as a series of blocks and slivers that are imbricated with originally intrusive Mesoarchaean TTG orthogneisse

Oxygen interaction with the Pd(112) surface: From chemisorption to bulk oxide formation

We investigated the interaction of oxygen with the Pd(112) surface from ultrahigh vacuum up to 5 mbars oxygen partial pressure in a temperature range from 523 to 673 K. We combined in situ surface x-ray diffraction with scanning tunneling microscopy, high-resolution core-level spectroscopy, and low-energy electron diffraction. A structural model of the clean Pd(112) is proposed based on the x-ray-

On Rapid Releases and Software Testing

Large open and closed source organizations like Google, Facebook and Mozilla are migrating their products towards rapid releases. While this allows faster time-to-market and user feedback, it also implies less time for testing and bug fixing. Since initial research results indeed show that rapid releases fix proportionally less reported bugs than traditional releases, this paper investigates the c

The effect of a biphasic injectable bone substitute on the interface strength in a rabbit knee prosthesis model.

In joint prosthetic surgery, various methods are used to provide implant stability. We used an injectable bone substitute, composed of calcium sulfate/hydroxyapatite, as bone defect filler to stabilize a tibia prosthesis in an experimental rabbit model. The aim of the study was to investigate and compare the stability of prosthetic fixation with and without the use of an injectable bone substitute

Hydrogen storage properties of the pseudo binary laves phase (Sc1-xZrx)(Co1-yNiy)(2) system

The (Sc1-xZrx)(Co1-yNiy)(2)-H-z system has been studied using both experimental techniques and ab initio calculations. The material was synthesised through high temperature synthesis and characterised using powder XRD. Hydrogen absorption and desorption was studied in-situ using synchrotron radiation. Maximal storage capacity increased when Co replaced Ni and substitution of Sc for Zr increased th