Filtyp
Our research focuses on aging and neurodegenerative diseases, aiming to improve understanding of disease mechanisms and support the development of biomarkers for clinical practice and clinical trials. We study fine-grained patterns of neurodegeneration, particularly in medial temporal lobe subregions that are affected early and selectively. Using structural MRI, imaging and biofluid markers, as
https://www.multipark.lu.se/medial-temporal-lab - 2026-10-29
Our research aims to generate specific subtypes of inhibitory brain cells, called interneurons, from human stem cells and patient-derived cells, using a technology known as neuronal reprogramming. Our goal is to develop interneuron cell replacement therapies for brain disorders. By reprogramming cells taken directly from patients, we create human disease-relevant models that allow us to investig
https://www.multipark.lu.se/regenerative-neurophysiology - 2026-10-29
We use positron emission tomography to elucidate disease mechanisms, monitor disease progression, and improve diagnosis in neurodegenerative disorders. Our group leads the PET imaging program within the BioFINDER studies, integrating tau PET, amyloid PET, dopamine transporter imaging, and cardiac sympathetic nervous system imaging. These modalities are combined with extensive biomarker profiling,
https://www.multipark.lu.se/pet-imaging-neurodegenerative-diseases - 2026-10-29
We focus on developing accurate methods for the early diagnosis of neurodegenerative diseases, e.g., Alzheimer's and Parkinson's disease. Our research also aims to unravel the pathological events in humans during the pre-symptomatic and prodromal stages. Finally, we work to improve clinical trials evaluating new disease-modifying therapies. An overview of our research cohorts can be found at Bio
https://www.multipark.lu.se/clinical-memory-research-unit-0 - 2026-10-29
Frontotemporal dementia is the second most common neurodegenerative dementing disorder. Our research focuses on two main areas: improving the diagnostic process through the use of biomarkers and understanding the core mechanisms of the disease. To achieve these aims, we use a variety of methods, including PET, MRI, and genetic analyses. Our research contributes to improved diagnosis of frontotempo
https://www.multipark.lu.se/frontotemporal-dementia-research-unit - 2026-10-29
Our lab specializes in transposable elements and their influence on human brain evolution, neurodegenerative diseases, brain tumors and ageing. We have expertise in human stem cell cultures, viral vectors, gene editing, cellular reprogramming, and the bioinformatic analysis of transposons. We study molecular processes that malfunction in age-related neurodegenerative disorders, using human post-mo
https://www.multipark.lu.se/molecular-neurogenetics - 2026-10-29
Huntington’s disease (HD) is characterised by classical neurological symptoms, and there is currently no disease-modifying therapy. Today, huntingtin-silencing strategies targeting the brain provide hope for HD patients and their families. However, pathology in HD is not limited to the brain. The causative gene, mutant huntingtin, is widely expressed throughout the body. Our research focuses on un
https://www.multipark.lu.se/brain-disease-biomarker-unit - 2026-10-29
Our research aims to uncover early mechanisms and biomarkers involved in neurodegenerative disorders such as Alzheimer’s disease and dementia with Lewy bodies. Our strategy is to examine how risk factors, including stress, inflammation, metabolic disturbances, and amyloidogenesis, affect cellular integrity in the brain and retina. We use a translational approach in which our hypotheses are built u
https://www.multipark.lu.se/cognitive-disorder-research-unit - 2026-10-29
Decreased gait speed precedes cognitive decline, and performing two tasks simultaneously (dual-tasking) increases the complexity. These findings inspired our ongoing work. Our overarching aim is to determine how different motor aspects and dual-task performance relate to early brain pathologies, cognitive decline, and neurodegenerative diseases, i.e., major neurocognitive disorders (dementia) and
https://www.multipark.lu.se/rehabilitation-neurodegenerative-diseases-render - 2026-10-29
Flow Cytometry Analysis and Fluorecence Activated Cell Sorting (FACS) Flow cytometry enables measurement of fluorescence intensity of particles (cells) in a liquid stream. Analysis of live and fixed cells may be based on size, granularity/complexity, fluorescent proteins, cell surface antigen expression, intracellular antigen expression, DNA content. Flow cytometry is ideal for multiplexing target
https://www.multipark.lu.se/infrastructures/facs-platform - 2026-10-29
Artificial intelligence/machine learning (AI/ML) knowledge base The usefulness of artificial intelligence/machine learning technologies in neuroscience spans from the practical to the abstract; they can be used to automatize labor-intensive analysis steps or for explorative analysis of large, complex data sets. They can even serve as model systems to study emergent properties of neural networks. T
https://www.multipark.lu.se/infrastructures/aiml-knowledge-base - 2026-10-29
Bengt Winblad Professor of Geriatrics, Karolinska Institutet, Stockholm Area: Alzheimers´s disease & related, clinical science Monica di Luca Professor of Pharmacology, University of Milan, Italy Area: Alzheimers´s disease & related, basic science Werner Poewe Professor of neurology, Medical University Innsbruck, Austria Area: Parkinson´s disease & related, clinical science Etienne Hirsch Profe
https://www.multipark.lu.se/multipark-external-advisory-board-eab - 2026-10-29
BACTERIA LAB In this lab bacteria are grown to produce DNA, which we use in further experiments such as viral vector production. RETROVIRAL VECTOR PRODUCTION This platform is used to produce viral vectors for gene transfer, both in vivo and in vitro. The vectors produced here are onco-retroviral and lentiviral vectors. The vectors can be produced at very high titers and used directly for in vivo
https://www.multipark.lu.se/infrastructures/bacteria-lab-retroviral-production - 2026-10-29
The behavioral platform offers setups for motor and cognitive testing. It consists of multiple laboratories and equipment to do complete a battery of motor and cognitive tests. The platform offers diversified arrays of behavioral tests in an environment that is very close to other state-of-the-art laboratory facilities. If you are interested in using the Behavioral Platform, or just want to know m
https://www.multipark.lu.se/infrastructures/behavioural-platforms - 2026-10-29
Joint facility between MultiPark and Stem Cell Center The joint Electrophysiology Core Facility, supported by MultiPark and Stem Cell Center at Lund University, provides researchers with access to advanced electrophysiology techniques and expert guidance for investigating electrically active cells and tissues, helping to bring their projects to the forefront of the field. We invite you to contact
https://www.multipark.lu.se/infrastructures/electrophysiology-core-facility - 2026-10-29
As of first of January 2022, StemTherapy and MultiPark have decided to merge the former iPSC, CRISPR and vector platforms into the new Cell and Gene Technologies Core. The Cell and Gene Technologies core is an open-access infrastructure and our services include AAV and LV vector production, iPS reprogramming, iPS-edits and CRISPR experimental designs. The core is open to members of MultiPark as w
https://www.multipark.lu.se/infrastructures/cell-and-gene-technologies-core - 2026-10-29
MultiPark helps you to grow as a scientist Flow cytometry courses are arranged in a collaboration between MultipPark FACS core facility and stem cell center FACS core, together with the associated graduate schools (Lund University neuroscience graduate school (LUNGS) and Research School in Stem Cell Biology (RSSCB)) Please click on the course of interest for more information about specific dates:
https://www.multipark.lu.se/lund-university-lu-neuroscience-graduate-school/courses-workshops - 2026-10-29
Aim and format The aim of this 3-day theoretical course is to give participants a working knowledge of flow cytometry covering the following aspects: Basic concepts of flow cytometry Instrumentation - basic principles of operation Techniques - cell handling, staining, designing of protocol Data acquisition and analysis Applications of flow cytometry Learning outcomes On completion of the course, t
Aim and format The course aims to provide a broad understanding of different aspects of flow cytometry, including experimental design, sample material handling, analysis of flow cytometry data, as well as file and image handling prior to research publication. The course provides practical knowledge of advanced flow cytometry that can be directly transferred to research questions. Learning outcomes
MultiPark's biobank sample collection Design and access to samples MultiPark's biobank sample collection (MPBC) is a resource that serve three major research areas: Biomarkers, Epidemiology and Genetics. Patients with confirmed idiopathic Parkinson diagnosis living in the region of Skåne were invited to participate. There are approximately 2-3000 Parkinson patients in the region of Skåne, whereof
https://www.multipark.lu.se/infrastructures/biobank-platform - 2026-10-29
