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Formalism and Instrumentalism in the Marxist Critique of Right : With What Must Pashukanian Theory Begin?

The critique of the legal form of capitalism by E. B. Pashukanis has risen to prominence once again. However, the negative origin of the concept of the legal form, the critique of formalism and instrumentalism, has received too little attention. This essay substantiates the significance of Pashukanis’s critique, avoiding both overly general and narrow conceptions. Moreover, it proposes that his negThe critique of the legal form of capitalism by E. B. Pashukanis has risen to prominence once again. However, the negative origin of the concept of the legal form, the critique of formalism and instrumentalism, has received too little attention. This essay substantiates the significance of Pashukanis’s critique, avoiding both overly general and narrow conceptions. Moreover, it proposes that his ne

A Low-Cost Method for Characterizing the Inception and Extent of Cavitation in High-Pressure Homogenizers

High-pressure homogenizers are prone to cavitation, which causes wear and influences breakup efficiency. However, the inception point, as well as the extent and intensity, depends on geometry, operation, and fluid properties. While several methods have been previously suggested to characterize cavitation in homogenizer valves (including ultrasonic methods), they have required highly specialized, s

Clinical significance of a new diagnosis of atrial fibrillation in patients with vascular disease

Background: The Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial enrolled patients with vascular disease but excluded patients requiring oral anticoagulation. Objective: We aimed to explore the clinical significance of a new diagnosis of atrial fibrillation (AF) during follow-up. Methods: New AF was identified from hospitalization, study drug discontinuation, and

The influence of three-gendered grammatical systems on simultaneous bilingual cognition : The case of Ukrainian-Russian bilinguals

This paper examines the linguistic relativity principle (Whorf, 1956) by investigating the impact of grammatical gender on cognition in simultaneous bilinguals of three-gendered Ukrainian and Russian. It examines whether speakers of three-gendered languages show grammatical gender effects on categorisation, empirically addressing claims that such effects are insignificant due to the presence of th

The Alzheimer's Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin study

INTRODUCTION: The Alzheimer's Association Global Biomarker Standardization Consortium conducted a blinded case–control study to learn which phosphorylated tau (p-tau) assays provide the largest fold-changes in Alzheimer's disease (AD) versus non-AD and show commutability in measuring patient samples and candidate certified reference materials (CRMs). METHODS: Thirty-three different p-tau assays me

A Review of International Approaches for Development of Climate Reference Periods – for Hygrothermal Analysis of Buildings

In recent years, Sweden has seen substantial changes to its building designs, especially regarding the envelope and ventilation systems, across both renovations and new constructions. Although enhancements like better insulation and new building materials have boosted energy efficiency, they have also led to moisture-related problems such as stains, mold, and decay. To address these issues, heat a

SELective defunctioning Stoma Approach in low anterior resection for rectal cancer (SELSA) : Protocol for a prospective study with a nested randomized clinical trial investigating stoma-free survival without major LARS following total mesorectal excision

Aim: Accumulated data suggest that routine use of defunctioning stoma in low anterior resection for rectal cancer may cause kidney injury, bowel dysfunction and a higher risk of permanent stomas. We aim to study whether avoidance of a diverting stoma in selected patients is safe and reduces adverse consequences. Methods: SELSA is a multicentre international prospective observational study nesting

Birthweight and risk of chronic kidney disease after a type 2 diabetes diagnosis in the DD2 cohort

Aims/hypothesis: Low birthweight (LBW) is associated with younger age, less obesity and more hypertension among people recently diagnosed with type 2 diabetes, as well as increased cardiovascular morbidity and mortality risk. It is not known whether LBW is associated with an increased risk of incident chronic kidney disease (CKD) among people with a type 2 diabetes diagnosis. Methods: Original mid

Confirmatory Biopsy Outcomes in Patients with Grade Group 2 Prostate Cancer : Implications for Early Management

Background and objective: Guideline recommendations regarding early management of grade group (GG) 2 prostate cancer with confirmatory biopsy (cBx) are not well established. Our aim was to determine which patients with GG 2 cancer should undergo cBx before treatment decision-making by evaluating the probability of downgrading to GG 1 or no cancer on cBx. Methods: This was a single-institution retr

Cardiac ATP production and contractility are favorably regulated by short-term S100A9 blockade after myocardial infarction

Introduction: The infarcted heart is energetically compromised exhibiting a deficient production of adenosine triphosphate (ATP) and the ensuing impaired contractile function. Short-term blockade of the protein S100A9 improves cardiac performance in mice after myocardial infarction (MI). The implications upon ATP production during this process are not known. Objectives: This study evaluates whethe

IgA vasculitis nephritis - outcomes in adult-onset disease

Objectives: IgA vasculitis (IgAV) in adults has been relatively under-investigated. Since outcomes are worse in other forms of vasculitis with increasing age, we investigated the outcomes of IgAV comparing younger adults (18-34), middle-aged adults (35-64) and elderly patients (≥64 years) focusing on kidney outcomes. Methods: We identified patients with renal biopsy-confirmed IgAV nephritis and co

Sleep-Administered ketamine/psychedelics : A streamlined strategy to address two challenges in research on ketamine and psychedelics

The dissociative effects of ketamine and psychedelics might be associated with their rapid antidepressant properties, raising questions about whether these effects are necessary for their therapeutic action. Additionally, the distinct dissociative experiences often reported by patients in clinical trials may reveal whether they receive an active treatment or a placebo, potentially introducing bias

Comparative Kinetics of Supported Lipid Bilayer Formation on Silica Coated Vertically Oriented Highly Curved Nanowires and Planar Silica Surfaces

Supported lipid bilayers (SLBs), formed via lipid vesicle adsorption on highly curved silica surfaces, are widely used in biosensor applications and as models for curved cell membranes. However, SLB formation is often hindered on convex structures with radii comparable to the vesicles. In this study, lightguiding semiconductor nanowires (NWs), engineered for fluorescence signal enhancement, were u

Vocal Communication in Domestic Cats

This article describes the phonetic characteristics of the most common vocalisation types and subtypes in the domestic cat: the meow, the trill, the howl, the growl, the hiss (and the spit), the snarl (and the cry), the purr, the chirp and the chatter. In addition, the contexts where the different sounds are normally produced, and accompanying body postures and movements are summarised. Acoustic dThis article describes the phonetic characteristics of the most common vocalisation types and subtypes in the domestic cat: the meow, the trill, the howl, the growl, the hiss (and the spit), the snarl (and the cry), the purr, the chirp and the chatter. In addition, the contexts where the different sounds are normally produced, and accompanying body postures and movements are summarised. Acoustic d