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Background: Many cancers are increased in immunosuppressed patients and evidence is accumulating that immune dysfunction may be a contributing risk factor for second primary cancers (SPCs). The aim of this study was to explore the potential influence of immune mechanisms in SPC. Methods: We used the Swedish Cancer Registry (1990-2015) to select 13 male and 14 female first primary cancers (FPCs) th

Microbe-mediated precipitation of Mn-oxides enriched in rare earth elements (REE) and other trace elements was discovered in tunnels leading to the main shaft of the Ytterby mine, Sweden. Defining the spatial distribution of microorganisms and elements in this ecosystem provide a better understanding of specific niches and parameters driving the emergence of these communities and associated minera

Background: In Scandinavia, there is a strong tradition for research and quality monitoring based on registry data. In Denmark, Norway and Sweden, 63 clinical registries collect data on disease characteristics, treatment and outcome of various cancer diagnoses and groups based on process-related and outcome-related variables. Aim: We describe the cancer-related clinical registries, compare organiz

This article draws on empirically derived illustrations of return to work and unemployment to critically explore how a narrow understanding of work pervades contemporary social policies and programmes. This is particularly relevant in economic and labour market transitions aligned with neoliberalism that individualise the social problem of unemployment and thus restrict occupational possibilities

Background: Diastasis of the rectus abdominis muscle is a common condition. There are no generally accepted criteria for diagnosis or treatment of diastasis of the rectus abdominis muscle, which causes uncertainty for the patient and healthcare providers alike. Methods: The consensus document was created by a group of Swedish surgeons and based on a structured literature review and practical exper

This thesis addresses drinking water quality and microbiology in full-scale drinking water distribution systems (DWDSs). It examines how UV irradiation and slow sand filters (SSFs) alter the water bacteriome, and how the biofilm in the DWDS affects the drinking water quality.In addition, the effects of installing a combined ultra­filtration and coagulation treatment stage on the pipe biofilm com­m

This is the first book to provide a comprehensive account of cultural and heritage tourism in the Middle East and North Africa (MENA) region and the many complexities that heritage sites and tourist attractions face. The MENA region has long been regarded as the cradle of Western and Arab civilisation and is the home of many of the world’s major religions. Because of this, the region is rich in he

The chapter outlines the main themes that emerge in discussing the futures of cultural heritage tourism in the MENA region. Six main themes are identified. The tensions between the social and economic dimensions of heritage are illustrated in the construction of heritage, especially for international and domestic tourists. These tensions are also to be found in the wat in which heritage is deliber

The Middle East and Sorth Africa (MENA) is a large, complex, and diverse region and is viewed as a huge centre of cultural and travel influence. Nevertheless, the region has been plagued by geopolitical tensions, political turmoil, instability, and conflict over the decades. The conflict-ridden and controversial image of the region in many tourism-generating markets has negatively affected the flo

Spinocerebellar ataxia type 3 (SCA3), caused by a CAG repeat expansion in the ataxin-3 gene (ATXN3), is characterized by neuronal polyglutamine (polyQ) ATXN3 protein aggregates. Although there is no cure for SCA3, gene-silencing approaches to reduce toxic polyQ ATXN3 showed promise in preclinical models. However, a major limitation in translating putative treatments for this rare disease to the cl

Detta är en postumt publicerad text av Ingrid Nilsson Motevasel, förkortad och lätt redigerad av Rosmari Eliasson-Lappalainen.

Human activities have a huge impact on the carbon cycle by modifying the landscape. Vegetation cover changes attributed to forest clearance and the expansion of agricultural land increases soil erosion, organic matter and other nutrient delivery from terrestrial to aquatic ecosystems. Long-term records of environmental variation at centennial to millennial time scales are essential for the assessm

The existing information supports the use of this material as described in this safety assessment. 2-Decanone was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog 2-heptanone (CAS # 110-43-0) show that 2-decanone is not expected to be ge

Climate change poses an existential crisis for tourism and destinations. Nordic researchers have been at the forefront of research on climate change impacts, adaptation and mitigation. The review provides a brief account of some of the main themes in Nordic climate change research from a regional and international perspective and potential future research directions. Key themes identified include

By exploiting the core-excitation-induced dissociation of O2, we find that the Auger emission exhibits a Doppler-like energy shift. We show this to be a manifestation of localization of the core hole and propose that the problem of core-hole localization versus delocalization in core-hole spectroscopies may be resolved by considering the nature of the measurement.