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Gene therapy for epilepsy: resculpturing synaptic transmission with neuropeptides
Intractable seizures and lack of effective antiepileptic drugs (AED) are severe and common conditions affecting many patients with epilepsy. Thus, there is an urgent need to develop new therapies in epilepsy. The search for novel treatments has identified several neuropeptide systems as potential targets for future therapeutic interventions. The neuropeptide Y (NPY) may represent one such target,
Polytraumatization in an adult national sample and its association with psychological distress and self-esteem
Objective: The objective of this study was to examine the prevalence of selfreported experiences of potential childhood traumas and polytraumatization, and to find cut-off values for different kinds of potential traumatic events in a national representative sample of adults in Sweden. In addition, to analyse the association between polytraumatization and both psychological distress and global self
Fast and Reliable Two-View Translation Estimation
It has long been recognized that one of the fundamental difficulties in the estimation of two-view epipolar geometry is the capability of handling outliers. In this paper, we develop a fast and tractable algorithm that maximizes the number of inliers under the assumption of a purely translating camera. Compared to classical random sampling methods, our approach is guaranteed to compute the optimal
Radioactivity Exploration from the Arctic to Antarctica. Part 5: The Tundra-94 expedition
The joint Swedish-Russian “Tundra Ecology-94” expedition during 1994 used the large Russian ice-breaking research vessel R/V Akademik Fedorov a platform and went along a coastline of 3500 km-from the Kola Peninsula 10°E to Kolyuchinskaya Bay 173°E. Radioactivity in air, seawater and sediment was explored at various locations along the route. The average of 7Be activity concentration in air over th
Investigation of Microstrip Antenna Array Stacked Structure Realized on LTCC for 60 GHz Band
This paper presents the 16-element antenna array with parasitic microstrip antenna single element. Antenna designed to operate at 60 GHz and its structure based on low-temperature cofired ceramic (LTCC) substrate. Gain more then 18 dBi and return loss bandwidth about 20% were obtained after antenna geometry parameters optimization
Characterization of human dopaminergic neurons in the developing mesencephalon and upon differentiation of stem cells- for replacement therapy in Parkinson´s disease
Popular Abstract in Swedish Hjärnan är ett av människans viktigaste organ och är det centra som styr våra känslor, minnen och sociala färdigheter. Hjärnan är också det organ som signalerar till musklerna i kroppen att utföra rörelser. När en person drabbas av Parkinsons sjukdom minskar signaleringen till musklerna, vilket medför att det blir svårt att röra sig och stelhet uppstår. Sjukdomen beror Cell-replacement therapy is a promising approach for treating patients with Parkinson ́s disease (PD). For this purpose, there is a need for developing a protocol that can generate high numbers of human transplantable mesencephalic dopaminer- gic (mesDA) neurons. For decades, studies have therefore been made in mouse and other model organisms in order to elucidate key-factors that can be used for
What successful branding looks like: a managerial perspective
Purpose - The purpose of this paper is to develop an understanding of the ways in which food companies can work with branding to perform better in the market. The authors achieve this purpose by comparing how different managers of food brands prioritise and evaluate their brands, in relation to a theoretical ideal framework. Design/methodology/approach - A survey of 77 managers of domestic and int
Carrier Frequency Offset and I/Q Imbalance Compensation for MB-OFDM Based UWB System
Tracking the shape-dependent sintering of platinum-rhodium model catalysts under operando conditions.
Nanoparticle sintering during catalytic reactions is a major cause for catalyst deactivation. Understanding its atomic-scale processes and finding strategies to reduce it is of paramount scientific and economic interest. Here, we report on the composition-dependent three-dimensional restructuring of epitaxial platinum-rhodium alloy nanoparticles on alumina during carbon monoxide oxidation at 550 K
On the suitability of carbon nanotube forests as non-stick surfaces for nanomanipulation
A carbon nanotube forest provides a unique non-stick surface for nanomanipulation, as the nanostructuring of the surface allows micro- and nanoscale objects to be easily removed after first being deposited via a liquid dispersion. A common problem for smooth surfaces is the strong initial stiction caused by adhesion forces after deposition onto the surface. In this work, carbon nanotube forests fa
READMISSION AFTER RADICAL PROSTATECTOMY. NATION-WIDE, POPULATION-BASED STUDY IN PCBASE SWEDEN
Some open questions in TDDFT: Clues from lattice models and Kadanoff-Baym dynamics
Two aspects of TDDFT, the linear response approach and the adiabatic local density approximation, are examined from the perspective of lattice models. To this end, we review the DFT formulations on the lattice and give a concise presentation of the time-dependent Kadanoff-Baym equations, used to asses the limitations of the adiabatic approximation in TDDFT. We present results for the density respo
Growth and characterization of superconducting beta-FeSe type iron chalcogenide nanowires
We have grown highly crystalline beta-FeSe type iron chalcogenide nanowires (NWs) by annealing thin film that is prepared by a pulsed laser deposition method. Three kinds of NWs with compositions of Fe0.8Se, Fe0.88Se0.32Te0.68 and Fe0.88Te0.91S0.09 have been prepared and carefully characterized by a high-resolution transmission electron microscope (HRTEM). The NWs reveal ideal tetragonal structure
Do we have something to say? From re-search to roi-search and back again
The Jewish Modernist : Isaac Grünewald in Bertel Hintze’s Art History
Oral and faecal microbiota in volunteers with hypertension in a double blind, randomised placebo controlled trial with probiotics and fermented bilberries
Two probiotic products containing either live Lactobacillus plantarum strain DSM 15313 or bilberries fermented by the same bacterial strain were tested for their antihypertensive potentials and their impact on the oral and the faecal microbiota in hypertensive adults. The results showed that consumption of the tested products for three months did not reduce the blood pressure in adults with hypert
History in the Plural
J/psi suppression at forward rapidity in Au plus Au collisions at root s(NN)=39 and 62.4 GeV
We present measurements of the J/psi invariant yields in root s(NN) = 39 and 62.4 GeV Au + Au collisions at forward rapidity (1.2 < vertical bar y vertical bar < 2.2). Invariant yields are presented as a function of both collision centrality and transverse momentum. Nuclear modifications are obtained for central relative to peripheral Au + Au collisions (R-CP) and for various centrality selections
Does the choice of EQ-5D tariff matter? A comparison of the Swedish EQ-5D-3L index score with UK, US, Germany and Denmark among type 2 diabetes patients.
To compare the performance of the recently developed Swedish experience-based time trade-off (TTO) valuation of the EuroQol-5D-3L (EQ-5D-3L) against the hypothetical-based TTO valuations from UK, US, Germany and Denmark.