Deficiencies of the early components of the classical complement pathway impair the actions of innate and humoral immunity and may lead to increased susceptibility to infections. We have studied the genetic basis of total C4B deficiency in a Finnish patient with recurrent meningitis, chronic fistulas and abscesses. The maternal chromosome carried a four-gene deletion including the C4B gene, and a

Two yeasts, Candida arabinofermentans PYCC 5603(T) and Pichia guilliermondii PYCC 3012, which show rapid growth on L-arabinose and very high rates of L-arabinose uptake on screening, were selected for characterization of L-arabinose transport and the first steps of intracellular L-arabinose metabolism. The kinetics of L-arabinose uptake revealed at least two transport systems with distinct substra

The article examines different attempts to analyse the Christian men's movement, Promise Keepers, and the fatherhood responsibility movement. Complexity used as an argument to abandon the search for a gender ideology in the movements is criticized. Despite the presence of complex features, for example, regarding Promise Keepers' view on gender roles in the family, there are common assumptions of g

Går det att undvika passiva studenter som fokuserar på tentaläsning? Räcker det att låta studenterna arbeta med problemlösning, laborationer och projektarbeten, eller måste kanske undervisningen omorganiseras? Kan man få studenterna att själva ta ansvar för sin inlärning, att läsa mer i boken och att arbeta mer aktivt med materialet? På en av våra grundkurser i matematisk statistik i Lund har vi m

Mechanisms controlling microbial degradation of dissolved organic matter (DOM) in aquatic environments are poorly understood, although microbes are crucial to global nutrient cycling. Bacterial cell wall components may be one of the keys in understanding the presence of slowly degrading DOM in nature. We found that dominant components of bacterial cell walls (D-amino acids (D-AA), glucosamine (Glu

The report contains abstracts of master theses (examensarbete) made at the Department of Automatic ControL, Lund, during the academic year 1979/80. During this year 14 theses were made by 18 students. The theses are written in Swedish with an English abstract.

Objective A common threonine481serine polymorphism (T481S) has been shown in vitro to strongly activate the chloride channel Kb (CLC-Kb) expressed in the kidney, and the 481S allele has been associated with human hypertension. The study aim was to evaluate the association of the T481 S polymorphism with blood pressure (BP) levels and the BP progression rate in Swedes. Design and methods The cardio

How can tools help structure tasks to make them cognitively easier to perform? How do artefacts, and our strategies for using them, develop over time in cognitively beneficial ways? These are two of the main questions that are explored in the five papers collected in this thesis. The first paper details an ethnographic study conducted on people cooking in their homes. The study is a first pass ov

Purpose: To compare the longitudinal suture model for bridging nerve defects with direct approximation under tension or with autologuos nerve grafting. Methods: Seven mm nerve defects in the rat sciatic nerve were repaired by either of these three methods. Evaluation was performed at twelve weeks by morphometry of the tibial nerve distal to the repair site and by weight of the gastrocnemius muscl

"This report presents the results of ten projects in which we have used microcalorimetric techniques to study processes in building materials. Except for in cement research, microcalorimetry has not been much used on building materials. The microcalorimetric technique is extremely versatile, mainly because it is a very basic property (heat) that is measured. We hope that this report may encourage

Plants of the partially self-incompatible perennial herb Brassica cretica, derived from contralled cross- and self-pollinations within each of seven populations, were raised under uniform conditions and scored for two measures of developmental stability, flower asymmetry (quantified as the difference in length and width between opposite petals) and cotyledon asymmetry (quantified as the difference

Premixed turbulent flame-based technologies are rapidly growing in importance, with applications to modern clean combustion devices for both power generation and aeropropulsion. However, the gain in decreasing harmful emissions might be canceled by rising combustion instabilities. Unwanted unsteady flame phenomena that might even destroy the whole device have been widely reported and are subject t

A scintillating fibre tracker is proposed to measure elastic proton scattering at very small angles in the ATLAS experiment at CERN. The tracker will be located in so-called Roman Pot units at a distance of 240 m on each side of the ATLAS interaction point. An initial validation of the design choices was achieved in a beam test at DESY in a relatively low energy electron beam and using slow off-th

Ferrochelatase, the enzyme catalyzing metallation of protoporphyrin IX at the terminal step of heme biosynthesis, was co-crystallized with an isomer mixture of the potent inhibitor N-methylmesoporphyrin (N-MeMP). The X-ray structure revealed the active site of the enzyme, to which only one of the isomers was bound, and for the first time allowed characterization of the mode of porphyrin macrocycle