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Colon cancer is the third most common cancer and a significant cause of cancer-related deaths worldwide. Metastasis is the most insidious aspect of cancer progression. Convincing data suggest that microRNAs (miRs) play a key function in colon cancer biology. We examined the role of miR-340-5p in regulating RhoA expression as well as cell migration and invasion in colon cancer cells. Levels of miR-
Substance abuse, conduct disorder (CD) and attention deficit/hyperactivity disorder (ADHD) are all known risk factors for developing aggressive behaviors, criminality, other psychiatric comorbidity and substance use disorders (SUD). Since early age of onset is important for aggravating the impact of several of these risk factors, the aim of the present study was to investigate whether young adult
In interstadial deposits, sand interbeds gain limited consideration in comparison with organic sediments, and therefore tend to be underrepresented in paleoenvironmental reconstructions. The Raunis site, central-eastern Latvia, is an example where organic beds have already gained some attention and been used to understand the complex interactions between advance and retreat of the Scandinavian Ice
Developing a better understanding of visitor perceptions and satisfaction is integral to gaining insights into the pressures that lead to both overtourism and the under-utilisation of tourist attractions, including natural areas. Despite longstanding recognition of their value in monitoring and evaluating change there is a dearth of longitudinal studies in tourism. This study examines changing pat
The advent of microfluidics in the 1990s promised a revolution in multiple industries from healthcare to chemical processing. Deterministic lateral displacement (DLD) is a continuous-flow microfluidic particle separation method discovered in 2004 that has been applied successfully and widely to the separation of blood cells, yeast, spores, bacteria, viruses, DNA, droplets, and more. Deterministic
Background: Most literature on second primary cancers (SPCs) focuses on possible factors, which may increase the risk of these cancers, and little attention has been paid for the overall incidence differences between first primary cancers (FPCs) and same SPCs. We wanted to compare the incidence rates for all common cancers when these were diagnosed as FPCs and SPCs after invasive and in situ squam
Spectacular long-distance migration has evolved repeatedly in animals enabling exploration of resources separated in time and space. In birds, these patterns are largely driven by seasonality, cost of migration, and asymmetries in competition leading most often to leapfrog migration, where northern breeding populations winter furthest to the south. Here, we show that the highly aerial common swift
This article approaches the subject of German film policy in Sweden during World War II from a new perspective. While several film scholars have mapped the connections between the German and Swedish film industries in the past, less is known about the German surveillance of Swedish film criticism, Swedish cinema audiences and Allied newsreel competitors. Drawing on previously overlooked archival m
This article reconsiders the Swedish filmmaker Gösta Werner’s experimental short film The Sacrifice (Midvinterblot, 1945) and places its production history in an ideological context. In this case study, the article shows that The Sacrifice, which depicts gruesome old Norse pagan rituals of sacrifice, threw light on the director’s collaboration with the Nazi controlled German film company Universum
Swedish filmmaker Arne Sucksdorff was recognized as an innovative documentary filmmaker in the 1940s and 1950s, but once his production moved internationally - first to India and then to Brazil - the authorial discourse on his production changed dramatically. This chapter maps the transnational production and circulation of his feature length documentaries The Flute and the Arrow (En djungelsaga,
This paper asks whether moral preferences in eight medical dilemmas change as a function of how preferences are expressed, and how people choose when they are faced with two equally attractive help projects. In two large-scale studies, participants first read dilemmas where they “matched” two suggested helping projects (which varied on a single attribute) so that they became equally attractive. Th
Under flera decennier var Svensk filmindustri (SF) Sveriges ledande producent och distributör av film till landets skolor. I detta kapitel analyseras hur denna privata aktör positionerade sig gentemot samhället under decennierna efter andra världskriget. Genom att studera tidskriften Svensk skolfilm och bildningsfilm visar kapitlet på att gränserna mellan begrepp som ”skolfilm”, ”bildningsfilm” oc
Summary: The existing information supports the use of this material as described in this safety assessment.2-Propanol, 1,1',1',1'-(1,2-ethanediyldinitrilo)tetrakis- was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from the target material and read-across an
The existing information supports the use of this material as described in this safety assessment. 2-Methylpropyl pentanoate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog ethyl 2-methylbutyrate (CAS # 7452-79-1) show that 2-methyl
Malignt neuroleptikasyndrom och serotonergt syndrom är två tillstånd som det är viktigt att även andra läkare än psykiatrer tänker på och känner igen. Petra Truedsson och medförfattare beskriver helt riktigt i en översikt i Läkartidningen [1] att det skulle behövas bättre kvalitet i det vetenskapliga underlaget för behandling av dessa tillstånd, i synnerhet för malignt neuroleptikasyndrom som är f
