In most clinical situations involving adenovirus infection, subgenus (subgroup) identification of an adenovirus isolate is as informative as a finer identification by serotype. A PCR method which allows the identification of human adenovirus isolates as members of subgenera A, B:1, B:2, C, D, E, or F is described. It is based on a simple (nonnested) PCR using primers which bind to regions immediat

This paper develops a model of human capital accumulation with on-the-job learning subject to obsolescence risk. The model analytically characterizes trade-offs of reforming the level of income tax progressivity and matches well income inequality in the US. An enriched version is used to quantitatively investigate optimal tax progressivity in the US. In contrast to standard models with exogenous i

We develop a long-horizon asset pricing model in which equity investments may damage future production/consumption possibilities through their climate impact. We derive a four-fund separation result and determine the stocks' equilibrium returns. Stocks that have a sufficiently adverse impact on the climate may appear to have positive alphas relative to the CAPM. We further link our equilibrium ret

This paper presents tractable two parameter stochastic processes of the drift-diffusion class in order to model economic processes with a focus on income. Starting from the resulting closed-form, cross-sectional distributions, easy-to-interpret expressions for mobility and inequality (including the popular Gini-coefficient) are derived. The general processes are applied to discuss income mobility

This paper presents a closed-form expression for the concave consumption function in a model with liquidity constraints and spanned labor and capital income risk. Local Marginal Propensities to Consume (MPCs) and buffer-stock savings are analytically characterized allowing to identify its determinants. Solutions for common examples of the Hyperbolic Absolute Risk Aversion (HARA) class are presente

Neutrophil granulocytes are specialized phagocytic cells that carry a collection of granules for regulated secretion, each with distinct constituents. The granules can be classified as azurophil (primary), developed first, followed in time by specific (secondary) granules gelatinase granules, and secretory vesicles. Stage- and tissue-specific transcription factors govern the successive expression

Azurocidin is a multifunctional endotoxin-binding serine protease homolog synthesized during the promyelocytic stage of neutrophil development. To characterize the biosynthesis and processing of azurocidin, cDNA encoding human preproazurocidin was stably transfected to the rat basophilic leukemia cell line RBL-1 and the murine myeloblast-like cell line 32D cl3; cell lines previously utilized to st

Neutrophils contain an assembly of granules destined for regulated secretion, each granule type with distinct constituents formed before terminal differentiation. The earliest granules are designated azurophil (primary), followed in time by specific (secondary), and gelatinase granules as well as secretory vesicles. Transcription factors regulate the genes for the granule proteins to ensure that e

Background. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea ) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker. We studied the performances of the EKFC equations in a large cohort of subjects according to

In this paper, I examine ideas on creation, nature, and the ethical self as conceptual-ized by the Ikhwān al-Ṣafāʾ (Brethren of Purity, fl. ca. 350–369/961–980) and al-Rāghibal-Iṣfahānī (d. before 409/1018), with a particular focus on Abū Ḥāmid al-Ghazālī(d. 505/1111). Drawing from the classical scholarship on kalā m, taṣawwuf, and falsafa,I analyze texts by these ethicists who wrote on nature an

BackgroundPatient education and dialogue are important when choosing a future treatment strategy for patients with chronic kidney disease. To support patients in their decision-making process, it is critical to provide information in a way that patients can understand. This study was conducted to understand how nephrologists view the goals of information sharing, the challenges involved, and the s

In this article we aim to highlight the potential of forgotten grave materials in our museum depositories for gaining insights into prehistoric life. By applying a multi-proxy approach to the skeletal remains of two graves of uncertain types from Falbygden in western Sweden, we were able to acquire new knowledge of burial practices, subsistence, health and mobility in Late Neolithic and Early BronIn this article we aim to highlight the potential of forgotten grave materials in our museum depositories for gaining insights into prehistoric life. By applying a multi-proxy approach to the skeletal remains of two graves of uncertain types from Falbygden in western Sweden, we were able to acquire new knowledge of burial practices, subsistence, health and mobility in Late Neolithic and Early Bron

Assessment of third molar development on dental radiograms is one of the most commonly used methods of forensic age estimation. Despite widespread use and numerous studies, there is a paucity of aggregated data on how well a fully mature third molar identifies adulthood (> 18 years), the most important threshold in a medicolegal context. Therefore, a systematic review and meta-analysis was conduct

AIMS: To evaluate the long-term clinical and economic outcomes associated with insulin detemir and neutral protamine hagedorn (NPH) insulin in combination with mealtime insulin aspart in patients with type 1 diabetes in Sweden, based on data from a two-year, multi-national, open-label, randomized, controlled trial.METHODS: Insulin detemir was associated with significant improvements in glycaemic c