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Despite significant reductions in acute-rejection rates with the introduction of calcineurin inhibitor (CNI)-based immunosuppressive therapy, improvements in long-term graft survival in renal transplantation have been mixed. Improving long-term graft survival continues to present a major challenge in the management of kidney-transplant patients. CNIs are a key component of immunosuppressive therap
Introduction. Erythropoiesis-stimulating agents (ESAs) are used in cancer therapy to reverse anaemia. It has been suggested that ESAs might improve treatment outcome by reducing tumour hypoxia, but ESAs might also increase tumour growth. In this work, the effect of recombinant human erythropoietin (rHuEpo) beta was investigated on a human head and neck squamous carcinoma cell (HNSCC) line in vitro
A mobile DIAL (differential absorption lidar) remote sensing system has been employed in the monitoring of industrial pollutant emissions. Measurements of sulfur dioxide and mercury vapor were performed at nine different Swedish industrial plants within the framework of a control program commissioned by the Swedish Environmental Protection Agency. Total atmospheric fluxes of these species could be
The aim of the newborn pain cry analysis is to test the hypothesis that cry can be used as a tool to detect signs of nocioceptive pain. Previous studies applying signal processing techniques to analyze the sound of these cries have been done. The subject of this paper is to adapt and improve the original method with the help of new signal processing methods. The pitch frequency is extracted from t
Cognitive and motivational effects of more neutral or androgynous-looking virtual characters versus more pronouncedly feminine-looking or masculine-looking virtual characters are explored. In a user study, 158 students aged 17-19 encountered four virtual characters that were visually manipulated to represent gender stereotypicality versus androgyny. One aim was to explore students’ attitudes towar
Future wireless systems envision higher speeds and more reliable services but at the same time face challenges in terms of bandwidth being a limited resource. Two promising techniques that can provide an increased throughput without requiring additional bandwidth allocation are multiple-input multiple-output (MIMO) systems and ultra-wideband (UWB) systems. However, the performance of such systems
Identification of cardiomyocyte nuclei has been challenging in tissue sections as most strategies rely only on cytoplasmic marker proteins(1). Rare events in cardiac myocytes such as proliferation and apoptosis require an accurate identification of cardiac myocyte nuclei to analyze cellular renewal in homeostasis and in pathological conditions(2). Here, we provide a method to isolate cardiomyocyte
Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by both neurological and systemic abnormalities. Immune activation is a well-established feature of the HD brain and we have previously demonstrated a widespread, progressive innate immune response detectable in plasma throughout the course of HD. In the present work we used multiplex ELISA to quantify levels of che
Dendrochronology and source-criticism - on the dating of the Romanesque rebuilding of the church in Stora Köpinge: The dendro-dating of a "Romanesque" apse to the late 13th C has been met with scepticism. Author discusses use and misuse of the traditional source criticism, and attempts a revaluation of the declining market place Store Köpinge and the growing town of Ystad nearby.
A subgroup of patients suffering from primary Sjögren's syndrome (pSS) display unexplained low levels of complement components C3 and/or C4 which is associated with increased risk of non-Hodgkin's lymphoma. C4b-binding protein (C4BP) is a major fluid-phase complement inhibitor which can influence C4 and C3 levels. Therefore we analysed C4BP levels in the sera of patients with pSS to better underst
Sveriges judar är liksom andra svenskar i hög grad sekulariserade. Det är därför ingen överraskning att de mer ser judendomen som en nationell tillhörighet än som en religion. Det passar bra i det svenska samhället där man idag uppskattar multikulturalism och förhåller sig reserverat till svensk nationalism.
Abstract in Spanish Más atención se está dando a la necesidad de integrar la gestión del riesgo en el trabajo de desarrollo para poder reducir así la vulnerabilidad de los pobres que viven en áreas urbanas. Usando El Salvador como estudio de caso, este artículo analiza el proceso de integración en dos sectores de desarrollo: planificación urbana y vivienda social. El objetivo es identificar de qué
