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The possible contribution of HLA-DRB3, -DRB4 and -DRB5 alleles to type 1 diabetes risk and to autoantibodies against insulin (IAA), GAD65 (GADA), IA-2 (IA-2A) or ZnT8 against either of the three amino acid variants, R, W or Q at position 325 (ZnT8RA, ZnT8WA, and ZnT8QA, respectively) at clinical diagnosis is unclear. Next generation sequencing (NGS) was therefore used to determine all DRB alleles

Doctors are expected to serve the patient in an unbiased and medically accurate manner. Yet, this does not prevent doctors and other medical staff from having pronounced views on whether the patient deserves care. Based on field notes from a cardiology clinic, this contradiction is discussed and analyzed. In directing the spotlight on what circumstances are pointed out by the staff when discussing

OBJECTIVE: Umbilical cord acid-base analysis is fundamental for assessing intrapartum hypoxia. The accuracy of arterial umbilical cord blood lactate, pH and base deficit to reflect a low 5-minute Apgar score and hypoxic ischemic encephalopathy (HIE) stage 2-3 was assessed, and new gestational age-adjusted reference standards were compared with traditional stationary reference values. DESIGN AND SA

This text deals with a very particular dilemma: how should I, a post-linguistic-turn gender historian, deal with the reality that women are constantly excluded from the continuing writing of the past (or are silenced in the history that is played out in front of my eyes) without falling back on the herstory tradition that the majority of us academics say we have left behind? The problem is discuss

An upper bound on the first-event error probability for maximum-likelihood decoding of fixed binary convolutional codes on the binary symmetric channel is derived. The bound is evaluated for rate1/2codes, and comparisons are made with simulations and with the bounds of Viterbi, Van de Meeberg, and Post. In particular, the new bound is significantly better than Van de Meeberg's bound for rates abov

SP har etablerat en databas med 180 rasade eller skadade tak. Det framgår, att det var övervägande stål- och träkonstruktioner, som hade rasat. Endast en skadad betongkonstruktion rapporterades. Byggnadernas ålder spänner över cirka 100 år, men 60 % är uppförda från 1980 och framåt. Taken är förhållandevis flacka. Ca 30 % är lantbruksbyggnader. De dominerande rasorsakerna är dimensioneringsfel och

To evaluate the long term effect on lower extremity function and working capacity after stenting of iliocaval vein segments for acute deep venous thrombosis (DVT) or chronic venous occlusive disease. During a 14 year period from November 1994 to October 2008, 114 patients with median age 36 (interquartile range [IQR], 27-48) years, 72 (63%) women, 72 (63%) with hypercoagulable disorders, with acut

or many insects, the polarization pattern of the blue sky serves as a compass cue for spatial navigation. E-vector orientations are detected by photoreceptors in a dorsal rim area of the eye. Polarized-light signals from both eyes are finally integrated in the central complex, a brain area consisting of two subunits, the protocerebral bridge and the central body. Here we show that a topographic re

Real-time garbage collection is essential if object-oriented languages (in particular, Java) are to become predictable enough for real-time embedded systems. Although techniques for hard real-time garbage collection exist, they are based on estimations of the maximum amount of referenced (live) memory. Such estimations may be difficult to derive manually for complex programs.We present techniques

Recent reports suggest that immigrants from Middle Eastern countries are a high-risk group for type 2 diabetes (T2D) compared with Swedes, and that the pathogenesis of T2D may be ethnicity-specific. Deregulation of microRNA (miRNA) expression has been demonstrated to be associated with T2D but ethnic differences in miRNA have not been investigated. The aim of this study was to explore the ethnic s