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The influence of fat stores on magnetic orientation in day-migrating Chaffinch, Fringilla coelebs

Earlier experimental studies have demonstrated the ability of day-migrating birds to perform migration under overcast skies, thereby indicating use of cues other than solar. The orientation behaviour of the chaffinch, a diurnal migrant, was investigated in orientation cage experiments during the autumn migration period. The aim of our experiments was to examine the relationship between different o

Acute leukaemia and malignant lymphoma patients’ experiences of disease, treatment and nursing care during the active treatment phase: an explorative study.

Five acute leukaemia or highly malignant lymphoma patients at a hospital in southern Sweden were interviewed about their daily living problems, their coping strategies and their opinions about the nursing care they received during the active phase of their treatment. In addition the EORTC QLQ-C30, the Global Life Quality and the Sense of Coherence scales were administered. The data were analysed f

Monoamine transporters in human endometrium and decidua.

BACKGROUND Monoamines play important roles in decidualization, implantation, immune modulation and inflammation. Furthermore, monoamines are potent vasoactive mediators that regulate blood flow and capillary permeability. Regulation of the uterine blood flow is important both during menstruation and pregnancy. Adequate monoamine concentrations are essential for a proper implantation and physiologi

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

It has recently been suggested that the rs738409 G allele in PNPLA3, which encodes adiponutrin, is strongly associated with increased liver fat content in three different ethnic groups. The aims of the present study were as follows: (1) to try to replicate these findings in European individuals with quantitative measures of hepatic fat content; (2) to study whether the polymorphism influences hepa

Transport Processes in Responding Lipid Membranes: A Possible Mechanism for the pH Gradient in the Stratum Corneum

The “acidic mantle” of the skin surface has been related to several essential functions of the skin, although the origin of the acidity is still obscure. In this paper, we investigate how different transport processes can influence the local proton concentration inside a membrane consisting of oriented lipid bilayers. This system is chosen as a simple model of the extracellular lipids in the upper

Characterization of type I procollagen N-proteinase from fetal bovine tendon and skin. Purification of the 500-kilodalton form of the enzyme from bovine tendon

Procollagen N-proteinase (EC 3.4.24.14) is the enzyme that specifically cleaves the NH2-terminal propeptides from type I procollagen. Two forms of N-proteinase with apparent molecular sizes of 300 and 500 kDa were found in partially purified preparations from fetal bovine tendon extracts. The 500-kDa form of enzyme was purified 16,000-fold with a recovery of 8% from the extracts of the tendons by

Covalently Linked Ruthenium(II)-Manganese(II) Complexes: Distance Dependence of Quenching and Electron Transfer

Continuing our development of artificial models for photosystem II in green plants, a series of compounds have been prepared in which a Ru(bpy)32+ photosensitizer is covalently linked to a manganese(II) electron donor. In addition to a trispicolylamine ligand, two other manganese ligands, dipicolylamine and aminodiacetic acid, have been introduced in order to study ligands that are appropriate for

Induction of ID2 expression by hypoxia-inducible factor-1: ARole in dedifferentiation of hypoxic neuroblastoma cells.

ID (inhibitor of differentiation/DNA binding) proteins, frequently deregulated in advanced human malignancies, can participate in multiple fundamental traits of cancer, such as block of differentiation, increased proliferation, tissue invasiveness, and angiogenesis. We have previously demonstrated that hypoxia decreases expression of neuronal marker genes in neuroblastoma, but induces genes expres

Chromosome ends in Chironomus tentans do not have long single-stranded overhangs characterizing canonical telomeres.

Single-stranded overhangs of the G-rich strand belong to the conserved features of telomeres composed of short telomeric repeats. These structures are thought to be essential for the maintenance of proper telomeric structure and function and the mechanism of their generation is telomerase-independent. We have examined the presence of single-stranded overhangs in Chironomus tentans, a dipteran inse

Improved fast correlation attacks on stream ciphers via convolutional codes

This paper describes new methods for fast correlation attacks, based on the theory of convolutional codes. They can be applied to arbitrary LFSR feedback polynomials, in opposite to the previous methods, which mainly focus on feedback polynomials of low weight. The results improve significantly the few previous results for this general case, and are in many cases comparable with corresponding resu

The home environment and quality of life-related outcomes in advanced old age: findings of the ENABLE-AGE project

With the present research, we further exploited the potential of the ENABLE-AGE Project, more precisely the Swedish and German data. We hypothesised that the magnitude of accessibility problems (MAP) in the home environment and external housing-related control beliefs (HCB) play a substantial role for a range of outcomes related to quality of life. Our sample at T1 consisted of 847 single-living a

Neutrophils and keratinocytes in innate immunity--cooperative actions to provide antimicrobial defense at the right time and place

The human neutrophil is a professional phagocyte of fundamental importance for defense against microorganisms, as witnessed by the life-threatening infections occurring in patients with neutropenia or with defects that result in decreased microbicidal activity of the neutrophil. Likewise, the skin and mucosal surfaces provide important barriers against infections. Traditionally, these major defens

Mechanism of the antigen formation of carvone and related alpha, beta-unsaturated ketones

In the present study, the mechanism for the antigen formation of alpha, beta-unsaturated ketones was investigated. A series of analogues of carvone ((5R)-5-isopropenyl-2-methyl-2-cyclohexenone) with altered chemical reactivity and with retained overall structure or with retained reactivity and altered three-dimensional structure were synthesized. These analogues were tested for cross-reactivity in

Corner singularities for elliptic problems: special basis functions versus ‘brute force’

A method is presented for the fast and accurate solution of elliptic boundary value problems on domains with corners. The method is based on integral equations and Nyström discretization. Close to corners two representations for the solution coexist — a pointwise representation and a representation in terms of special basis functions. Mappings and kernel evaluations are constructed on a symmetric

Long crack behavior in a thermal barrier coating upon thermal shock loading

The behavior of macroscopic long cracks in the ceramic top coat of a thermal barrier coating (TBC) system subjected to thermal shock loading and the influence of the cracks on the coating durability were investigated experimentally and numerically. Thermal shock testing was conducted until coating failure. Comparisons were made with coating samples without macroscopic cracks. The experimental resu

Direct evidence of secondary necrosis of neutrophils during intense lung inflammation.

Several pulmonary inflammatory conditions are characterised by infiltration of neutrophils. Normally, neutrophils are silently removed by apoptosis, followed by phagocytosis. However, if phagocytosis fails, apoptotic cells undergo secondary necrosis. Recent findings of increased levels of the pan-necrosis marker lactate dehydrogenase in bronchoalveolar lavage from lipopolysaccharide-exposed mice i

Late Pleistocene remains of giant deer (Megaloceros giganteus Blumenbach) in Scandinavia: chronology and environment

This article presents new data on the Late Pleistocene giant deer, Megaloceros giganteus (Blumenbach), describing its distribution in time and space, geographical and sexual variation and general biology. Twenty-three south Scandinavian fossils found in situ in lacustrine sediments or redeposited in glaciofluvial material form the basis of this investigation. Fourteen C-14 dates show that the gian

Non-neutral community dynamics: empirical predictions for ecosystem function and diversity from linearized consumer–resource interactions

A general model of linearized species interactions, essentially Lotka–Volterra theory, applied to questions of biodiversity has previously been shown to be a powerful tool for understanding local species–abundance patterns and community responses to environmental change for a single trophic level. Here this approach is extended to predict community composition and responses to environmental change

Immunomodulation in surgical practise

Background. Immunomodulation may represent a potential way to improve surgical outcome. These types of interventions should be based on detailed knowledge of the underlying mechanisms involved. The aim of the present review is to summarize some experience on the acute phase response, potential ways of intervention and experiences from critical illness and HPB disease. Discussion. Mechanisms of the