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EPID dosimetry: Effect of different layers of materials on absorbed dose response

Purpose: Commercial EPIDs are normally used in indirect detection mode (iEPID) where incident x-ray photons are converted to optical photons in a phosphor scintillator, which are then detected by a photodiode array. The EPIDs are constructed from a number of nonwater equivalent materials which affect the dose response of the detector. The so-called direct detection EPIDs (dEPIDs), operating withou

Alpha-Photon Coincidence Spectroscopy Along Element 115 Decay Chains

Produced in the reaction 48Ca+243Am, thirty correlated α-decay chains were observed in an experiment conducted at the GSI Helmholzzentrum für Schwerionenforschung, Darmstadt, Germany. The decay chains are basically consistent with previous findings and are considered to originate from isotopes of element 115 with mass numbers 287, 288, and 289. A set-up aiming specifically for high-resolution char

Who do you think you are? - Personality in eating disordered patients.

The Five-Factor Model of personality is strongly linked to common mental disorders. Yet the relationship between the lower order personality traits (facets) of the model and eating disorder (ED) features remains unclear. The aim of the study was to explore how patients with non-anorexic ED differ from controls in personality and to examine the ability of personality facets to explain psychopatholo

Alteration in contractile G-protein coupled receptor expression by moist snus and nicotine in rat cerebral arteries

The cardiovascular risk for users of use of Swedish snus/American snuff (moist tobacco) has been debated for a long time. The present study was designed to examine the effects of water- or lipid-soluble (DMSO-soluble) snus and nicotine, the most important substance in tobacco, on the expression of vasocontractile G-protein coupled receptors (GPCR), such as endothelin ETB, serotonin 5-HT1B, and thr

Laser generated 300 keV electron beams from water

Abstract in Undetermined300 keV electron beams with energy peaked in the range 280–390 keV were generated by focusing a high contrast ratio but temporally double pulsed 800 nm ultrafast laser onto a flowing water jet under both helium atmosphere at ambient pressure and water aspirator vacuum conditions, using laser intensities in the range 1015–1018 Wcm−2. Their characteristics have been investiga

Behavior of silk protein at the air-water interface

The inability to link silk biomacromolecules' activity to their self-assembly and further fiber formation has limited a true implementation of a silk biotechnology. In this paper, we describe the application of video-enhanced drop shape analysis and interfacial shear rheological measurement to characterize the dynamic surface activity and interfacial interactions, as well as molecular structure wi

Streptococcus pyogenes - a manipulator of human defences

Streptococcus pyogenes is a major human pathogen with more than 500 000 casualties annually of which at least 163 000 are due to invasive infections. The remainder is due to post-streptococcal complications with rheu¬matic heart disease constituting the majority. S. pyogenes also causes milder infections such as skin infections and pharyngitis with an estimation of more than 700 million cases each

Decreased activities of apolipoprotein m promoter are associated with the susceptibility to coronary artery diseases.

The present study investigated the correlation among genetic polymorphisms of the proximal promoter region of apolipoprotein M (apoM) gene, the polymorphisms in relation to apoM expressions and the susceptibility to coronary artery diseases (CAD) in a Han Chinese population. Four common polymorphic sites, i.e., T-1628G, C-1065A, T-855C and T-778C, were confirmed, and a new deletion mutation C-724d

Mechanism of Quenching of Superconductivity in the YBa2Cu3O7-Delta System on Substitution of Zn For Cu

Substituting Zn for Cu is known to rapidly quench superconductivity in the doped perovskites but the mechanism behind it is still not clearly understood. Single phase YBa2(Cu1-xZnx)(3)O7-delta (x=0.0 to 0.06) samples were synthesized and characterized using XRD, wet titration, resistivity, and ac susceptibility. Angle-integrated Valence Band Photo emission and Zn K-edge XAFS results clearly show t

Phosphorylation of Serine 248 of C/EBP alpha Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

Background: Transcription factors play a key role in lineage commitment and differentiation of stem cells into distinct mature cells. In hematopoiesis, they regulate lineage-specific gene expression in a stage-specific manner through various physical and functional interactions with regulatory proteins that are simultanously recruited and activated to ensure timely gene expression. The transcripti

Aral Sea syndrome desiccates Lake Urmia: Call for action

Lake Urmia, one of the largest saltwater lakes on earth and a highly endangered ecosystem, is on the brink of a major environmental disaster similar to the catastrophic death of the Aral Sea. With a new composite of multi-spectral high resolution satellite observations, we show that the area of this Iranian lake has decreased by around 88% in the past decades, far more than previously reported (~

Snus (Swedish smokeless tobacco) use and risk of stroke: pooled analyses of incidence and survival

Background. Snus is a moist smokeless tobacco product with high nicotine content. Its use has a short-term effect on the cardiovascular system, but the relationship between snus use and stroke is unclear. Objective. The aim of this study was to assess the associations between use of snus and incidence of and survival after stroke, both overall and according to subtypes. Methods. Pooled analyses of

Communicating Alcohol Narratives: Creating a Healthier Relationship with Alcohol

Alcohol, like mental health, is a neglected topic in public health discussions. However, it should be defined as a priority public health area because the evidence available to support this is very persuasive. Although only half the world's population drinks alcohol, it is the world's third leading cause of ill health and premature death, after low birth weight and unsafe sex, and the world's grea

A real-life cost-effectiveness evaluation of budesonide/formoterol maintenance and reliever therapy in asthma

Objective: To evaluate direct asthma-related costs in Swedish primary care in a real-life setting. Design: 12-month open-label study. Setting: Swedish primary care in a real-life setting. Participants: 1776 patients with persistent asthma. Interventions: Patients with persistent asthma were randomised to one of three treatments: a free adjustable combination of budesonide (100-400 mu g/inhalation)

Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report

This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case-control studies report this association, but retrospective phase III trial analyses show no increased risk. Bisphosphonate use may be associated with atypical subtrochanteric fractures, but the case is yet unproven. A Working Group o

Prospective evaluation of glutamine and phospholipids levels in first degree relatives of patients with Type 1 Diabetes from a multiethnic population.

A dysregulation in the metabolism of lipids may be an early marker of autoimmunity in Type 1 Diabetes (T1D). It would be of general importance to identify metabolic patterns that would predict the risk for T1D later in life. The aim of this study was to perform a prospective evaluation of glutamine and phospholipids levels in Brazilian first degree relatives (FDR) of patients with T1D in a mean in