The focus of this thesis is on cerebellar-dependent sensorimotor tasks during development. The performance in classical delay eyeblink conditioning, prism adaptation, and isochronous serial interval production (finger tapping) was explored in typically developing school-aged children, young adolescents, and adults. These three tasks share that the cerebellum plays a critical role when it comes to

Timing and indication for pulmonary valve replacement (PVR) in patients with repaired Tetralogy of Fallot (rToF) and pulmonary regurgitation (PR) are uncertain. To improve understanding of pumping mechanics, we investigated atrioventricular coupling before and after surgical PVR. Cardiovascular magnetic resonance (CMR) were performed in patients (n=12) with rToF and PR>35% before and after PVR and

Background conditions are thought to explain how objects can have value in virtue of certain features and how reasons can consist in certain facts. The following paper provides an account of what background conditions are and what effect they have on normative features. It defends the idea that if values depend on reasons, then there is nothing really surprising or mysterious about the presence of

Accurately quantifying soil base cation pool sizes is essential to interpreting the sustainability of forest harvests from element mass-balance studies. The soil-exchangeable pool is classically viewed as the bank of "available" base cations in the soil, withdrawn upon by plant uptake and leaching and refilled by litter decomposition, atmospheric deposition and mineral weathering. The operational

Over the past decades, the field of in vivo magnetic resonance (MR) has built up an impressive repertoire of data acquisition and analysis technologies for anatomical, functional, physiological, and molecular imaging, the description of which requires many book volumes. As such it is impossible for a few authors to have an authoritative overview of the field and for a brief article to be inclusive

Harold Bloom, in the Western Canon, selected only twenty-six sine qua non writers and, invoking Giambattista Vico’s New Science, where human history was distributed in three phases – Theocratic, Aristocratic, and Democratic – introduced another one, the Chaotic Age (represented by Freud, Proust, Joyce, and Kafka).1 Bloom did not expel this newly proposed Age, as it was also the container of beauty

PURPOSE: To compare the two major complications, namely postoperative urethrocutaneous fistula and urethral stricture, between the Mathieu and tubularized incised plate (TIP) repair methods for distal hypospadias.METHODS: In this meta-analysis, electronic databases were searched for comparative studies on the two techniques. The Oxford Centre for Evidence-based Medicine Levels of Evidence was used

An x-ray spectrometer includes: an x-ray plasma source that produces first x-rays; an x-ray optic in optical communication with the x-ray plasma source and that: receives the first x-rays from the x-ray plasma source; focuses the first x-rays to produce second x-rays; and communicates the second x-rays to a sample that produces product x-rays in response to receipt of the second x-rays and second

The protein parkin, encoded by the PARK2 gene, is vital for mitochondrial homeostasis, and although it has been implicated in Parkinson’s disease (PD), the disease mechanisms remain unclear. We have applied mass spectrometry-based proteomics to investigate the effects of parkin dysfunction on the mitochondrial proteome in human isogenic induced pluripotent stem cell-derived neurons with and withou

Objective: To develop evidence-based guidelines for the management of giant cell arteritis (GCA) as a complement to guidelines in other areas of rheumatology, issued by the Swedish Society of Rheumatology. Methods: A working group selected key areas for recommendations, reviewed the available evidence, and wrote draft guidelines. These were discussed and revised according to standard procedures wi

Aims. We have measured and calculated lifetimes of high lying levels in Nb II, and derived absolute transition probabilities by combining the lifetimes with experimental branching fractions. Methods. The lifetimes were measured using time-resolved laser-induced fluorescence in a two-photon and two-step excitation scheme. The branching fractions were measured in intensity calibrated spectra from a

Background: Nail polish is known to contain potentially hazardous chemicals that have been linked to adverse health effects after overexposure. Formaldehyde is used as an antimicrobial, preservative, and nail hardener in select nail products, yet it is a recognized carcinogen and potent allergen in allergic contact dermatitis. Objective: The aim of this study was to investigate whether formaldehyd

Recently, seven Earth-sized planets were discovered around the M-dwarf star TRAPPIST-1. Thanks to transit-timing variations, the masses and therefore the bulk densities of the planets have been constrained, suggesting that all TRAPPIST-1 planets are consistent with water mass fractions on the order of 10%. These water fractions, as well as the similar planet masses within the system, constitute st

Palliative care philosophy is based on a holistic approach to patients, but research shows that possibilities for living up to this philosophy seem limited by historical and administrative structures. From the nurse perspective, this article aims to explore nursing practice in specialised palliative homecare, and how it is influenced by organisational and cultural structures. Qualitative, semi-str

Discussions and debates about traditional values of equity and inclusion have increased in recent years, and participants in these discussions include professional heritage institutions, journalists of the daily press and the public through social media. Museums, as keepers of cultural stories and heritage under their auspices, are increasingly examining their role in shaping a narrative of divers

This thesis treats the intersection between two of the largest transformations we are seeing within our society today; the cloud and the Internet-of-Things (IoT). The aim of this thesis is to investigate different ways to model and control a network of cloud services so that timing-critical IoT applications can make use of them. Examples of such applications can be autonomous and mobile robots, sm