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Delayed Onset of Ototoxic Effects of Gentamicin in Patients with Meniére's Disease

In treatment of Meniére's disease, installations of gentamicin are continued until there are signs of disturbance of vestibular or cochlear function. However, since it has been demonstrated that gentamicin is eliminated slowly from the inner ear, a continuing ototoxic effect may be suspected. The present study aimed to investigate the delay of onset of symptoms of ototoxic effects. Five patients w

Latent Autoimmune Diabetes in Adults: Definition, Prevalence, {beta}-Cell Function, and Treatment.

Latent autoimmune diabetes in adults (LADA) is a disorder in which, despite the presence of islet antibodies at diagnosis of diabetes, the progression of autoimmune ß-cell failure is slow. LADA patients are therefore not insulin requiring, at least during the first 6 months after diagnosis of diabetes. Among patients with phenotypic type 2 diabetes, LADA occurs in 10% of individuals older than 35

Changes of bone mineral mass and soft tissue composition after hip fracture

The aim of this prospective longitudinal study was to measure prospectively the bone mineral density (BMD) and anthropometric variables after a hip fracture. In particular, we studied changes in the BMD in both the injured and uninjured hips, and examined if the postoperative mortality rate and complications, including pseudarthrosis of the fracture and late segmental collapse of the head of the f

Association between SLE nephritis and polymorphic variants of the CRP and Fc gamma RIIIa genes

Objectives. To study the relationship between clinical manifestations in systemic lupus erythematosus (SLE) with polymorphisms in suggested susceptibility genes encoding Fc gamma RIIa, Fc gamma RIIIa, Fc gamma RIIIb, CRP and IL-1Ra. Methods. Genetic polymorphisms were analysed in 323 unrelated SLE patients and 200 healthy blood donors. The genotype frequencies were compared between clinical subset

Managing cardiovascular risk: reality vs. perception

Clinical practice guidelines attempt to bridge the gap between the generation of scientific evidence and its application. For cardiovascular risk reduction, the implementation of knowledge into practice, both with respect to lifestyle change and pharmacological treatment, has been shown to be poor. There are several reasons for this 'guidelines gap', with physician factors including insufficient t

CO2 induced acute respiratory acidosis and brain tissue intracellular pH: a P-31 NMR study in swine

High concentration carbon dioxide (CO2) is used to promote pre-slaughter anaesthesia in swine and poultry, as well as short-lasting surgical anaesthesia and euthanasia in laboratory animals. Questions related to animal welfare have been raised, as CO2 anaesthesia does not set in momentarily. Carbon dioxide promotes anaesthesia by lowering the intracellular pH in the brain cells, but the dynamics o

Titchmarsh-Weyl M-function asymptotics and some results in the inverse spectral theory for vector-valued Sturm-Liouville equations and a certain higher order ordinary differential equation

Popular Abstract in Swedish Denna avhandling utgöres av två separata rapporter, där studieobjektet för den första är en vektorvärd Sturm-Liouville ekvation på formen -(PU')'+QU=zU, xin[0,b), med P^{-1},W,Q hermiteska med lokalt integrerbara matriselement; och under vissa ytterligare villkor på P^{-1} och W. Under dessa förutsättningar härleds några huvudresultat beträf- fande asymptotiken, då z igThis discourse is constituted by two separate reprots, where the first one offers an elementary deduction of the leading order term asymptotics for the Titchmarsh-Weyl M-function corresponding to a vector-valued Sturm-Liouville equation of the form -(PU')'+QU=zu, xin[0,b), with P^{-1},W,Q being hermitean with locally integrable entries; and under some additional conditions on P^{-1} and W. In the

Misplaced Concreteness and Concrete Places : Critical Analyses of Divergent Discourses on Sustainability

Popular Abstract in Swedish Denna avhandling bygger på en kritisk granskning av spänningen mellan etablerade och alternativa perspektiv på hållbarhetsproblematiken, med utgångspunkt i fyra olika diskurser: miljöekonomi, ekologisk ekonomi, adaptive management och bioregionalism. De fyra diskurserna representerar olika försök att i tilltagande grad utmana etablerade, modernistiska perspektiv på sociThis dissertation critically examines the tension between mainstream and counterpoint perspectives on sustainability on the basis of analyses of four approaches to this issue: environmental economics, ecological economics, adaptive management, and bioregionalism, which are presented as successive attempts to challenge mainstream, modernist perspectives on socio-ecological relationships. The differ

Time-domain Fresnel-to-Fraunhofer diffraction with photon echoes

A photon echo experiment in Tm3+:YAG is reported that shows, for the first time to the authors’ knowledge, the time-domain equivalent of the transition from near- to far-field diffraction, including Talbot self-imaging effects. The experiment demonstrates the huge dispersion capability of photon echoes and opens the way to further exploration of space–time duality.

alpha-, r-, and s-process element trends in the Galactic thin and thick disks

From a detailed elemental abundance analysis of 102 F and G dwarf starswe present abundance trends in the Galactic thin and thick disks for 14elements (O, Na, Mg, Al, Si, Ca, Ti, Cr, Fe, Ni, Zn, Y, Ba, and Eu).Stellar parameters and elemental abundances (except for Y, Ba and Eu)for 66 of the 102 stars were presented in our previous studies (Bensbyet al. 2003, 2004a). The 36 stars that are new in t

Visual analog scales for interpretation of back and leg pain intensity in patients operated for degenerative lumbar spine disorders

STUDY DESIGN: A prospective observational study of visual analog scale (VAS) scores for pain in patients operated at one institution within the framework of a national registry. OBJECTIVE: To describe the use of recording VAS for pain intensity in patients operated on for lumbar spine problems. SUMMARY OF BACKGROUND DATA: There is no consensus regarding pain outcomes assessment in spine patients.

Digital Hardware Aspects of Multiantenna Algorithms

The field of wireless communication is growing rapidly, with new requirements for the next generation of mobile and wireless communications technology. In order to achieve the capacities needed for future wireless systems, the design and implementation of advanced communications techniques such as multiantenna systems is required. These systems are realized by computationally complex algorithms, r

Properties of the L function

We study the function $L(t) = inf_{0 < x < 1}(x^p + t(1-x)^q)$ and related functions which arise in the theory of interpolation spaces.

Neural transplantation: restoring complex circuitry in the striatum

During the last 30 years, the promise of neural transplantation as a therapeutic strategy for neurodegenerative disease has been slowly recognised. Across the world, clinical transplants of embryonic primary dopamine neurones have been shown to ameliorate some of the motor deficits in Parkinson s disease (PD) patients, and more recently, systematic clinical trials have been initiated for the repla

Självkonfrontation via intern television i lärarutbildningen : Försök att modifiera lärarkandidaters perception och värdering med hjälp av videobandförmedlad självkonfrontation och traditionell handledning

This monograph contains a description and discussion of self-assessment data obtained from student teachers, who have participated in a self-confrontation experiment. The measurement scale: Assessment and Evaluation Schedule, has been especially devised for this experiment. The report includes a discussion of validity and reliability problems. The self-assessment data have been analysed by means o