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The impact of ethnicity on glucose homeostasis after gestational diabetes mellitus.

The objective of this study was to examine measures of insulin resistance and beta cell function in relation to ethnicity and the development of diabetes after gestational diabetes mellitus (GDM). Glucose homeostasis was assessed during a 75 g oral glucose tolerance test 1-2 years after delivery in 456 women with previous GDM (362 European, 94 non-European; including 41 Arab and 43 Asian women) an

Coulomb Excitation of 104Sn and the Strength of the 100Sn Shell Closure

A measurement of the reduced transition probability for the excitation of the ground state to the first 2(+) state in Sn-104 has been performed using relativistic Coulomb excitation at GSI. Sn-104 is the lightest isotope in the Sn chain for which this quantity has been measured. The result is a key point in the discussion of the evolution of nuclear structure in the proximity of the doubly magic n

Context-dependent effects of yolk androgens on nestling growth and immune function in a multi-brooded passerine.

Female birds may adjust their offspring phenotype to the specific requirements of the environment by differential allocation of physiologically active substances into yolks, such as androgens. Yolk androgens have been shown to boost embryonic development, growth rate and competitive ability of nestlings, but they can also entail immunological costs. The balance between costs and benefits of androg

No evidence for shedding of circulating tumor cells to the peripheral venous blood as a result of mammographic breast compression.

This pilot study aimed to investigate whether mammographic compression procedures might cause shedding of tumor cells into the circulatory system as reflected by circulating tumor cell (CTC) count in peripheral venous blood samples. From March to October 2012, 24 subjects with strong suspicion of breast malignancy were included in the study. Peripheral blood samples were acquired before and after

Pharmacokinetic modeling of enterohepatic circulation of mycophenolic acid in renal transplant recipients.

Several factors contribute to mycophenolic acid (MPA) between-patient variability. Here we characterize the metabolic pathways of MPA and quantify the effect of combining genetic polymorphism of multidrug-resistant-associated protein-2, demographics, biochemical covariates, co-medication (cyclosporine (CsA) vs. macrolides), and renal function on MPA, 7-O-MPA-glucuronide (MPAG), and acyl-glucuronid

Molecular characterization of Haemoproteus sacharovi (Haemosporida, Haemoproteidae), a common parasite of columbiform birds, with remarks on classification of haemoproteids of doves and pigeons

Haemoproteus (Haemosporida, Haemoproteidae) is the largest genus of avian haemosporidian parasites, some species of which cause lethal diseases in birds. Subgenera Parahaemoproteus and Haemoproteus are usually accepted in this genus; these parasites are transmitted by biting midges (Ceratopogonidae) and hippoboscid flies (Hippoboscidae), respectively. As of yet, species of Parahaemoproteus have no

Microbial Diversity and PAH Catabolic Genes Tracking Spatial Heterogeneity of PAH Concentrations.

We analyzed the within-site spatial heterogeneity of microbial community diversity, polyaromatic hydrocarbon (PAH) catabolic genotypes, and physiochemical soil properties at a creosote contaminated site. Genetic diversity and community structure were evaluated from an analysis of denaturant gradient gel electrophoresis (DGGE) of polymerase chain reaction (PCR)-amplified sequences of 16S rRNA gene.

Cardiovascular Health Effects of Internet-Based Encouragements to Do Daily Workplace Stair-Walks: Randomized Controlled Trial

Background: Although the hazardous health effects of a sedentary lifestyle are well known, many adults struggle with regular physical activity. Simple and efficient encouragements for increased physical activity are needed. Objective: To determine the effect on cardiovascular health of email-based encouragements to do daily stair-walks at work together with colleagues among adults in sedentary oc

An Efficient State Recovery Attack on the X-FCSR Family of Stream Ciphers

We describe a state recovery attack on the X-FCSR family of stream ciphers. In this attack we analyse each block of output keystream and try to solve for the state. The solver will succeed when a number of state conditions are satisfied. For X-FCSR-256, our best attack has a computational complexity of only 2^{4.7} table lookups per block of keystream, with an expected 2^{44.3} such blocks before

Valence electronic structure and photofragmentation of 1,1,1,2-tetrafluoroethane (CF3-CH2F)

The electronic structure and fragmentation of the hydrofluorocarbon compound 1,1,1,2-tetrafluoroethane (CF3-CH2F) were studied using spectroscopical methods and quantum chemical calculations. Valence photoelectron spectra and the ionic fragmentation products were recorded with synchrotron radiation in the vacuum ultraviolet (VUV) region. The geometric and electronic structures of the CF3-CH2F mole

Land-use change in the Caucasus during and after the Nagorno-Karabakh conflict

Socioeconomic shocks can shape future land-use trajectories. Armed conflicts are an extreme form of a socioeconomic shock, but our understanding of how armed conflicts affect land-use change is limited. Our goal was to assess land-use changes related to the 1991–1994 Nagorno-Karabakh conflict between Armenia and Azerbaijan in the Caucasus region. We classified multi-temporal Landsat imagery, mappe

On the Exploitation of Mid-infrared Iridescence of Plumage for Remote Classification of Nocturnal Migrating Birds

A challenging task in ornithology lies in identifying high-altitude nocturnal migrating bird species and genders. While the current approaches including radar, lunar obscuration, and single-band thermal imaging provide means of detection, a more detailed spectral or polarimetric analysis of light has the potential for retrieval of additional information whereby the species and sex could be determi

Click Reaction Synthesis and Photophysical Studies of Dendritic Metalloporphyrins

Several dendritic zinc(II)-porphyrins bearing carbazole units at the terminals have been prepared through click reaction of azide-substituted Zn-porphyrin precursors and carbazole-based alkynes under [Cu(NCCH3)(4)][PF6] catalysis. This family of new dendritic metalloporphyrins shows dual luminescence from both the upper S-2 and the lowest S-1 singlet states. The observed trends in the spectroscopi

Effect of pharmacological treatment for urinary incontinence in the elderly and frail elderly: A systematic review

Aim: The prevalence and severity of urinary incontinence (UI) increase with age and comorbidity. The benefits of pharmacotherapy for UI in the elderly are questionable. The aim of the present study was to systematically review the efficacy of pharmacological treatment for UI in the elderly and frail elderly. Methods: We searched PubMed, EMBASE, Cochrane library and Cinahl databases through October

Quantitative assessment of the antiviral potencies of 21 shRNA vectors targeting conserved, including structured, hepatitis B virus sites

Background & Aims: RNA interference (RNAi) may offer new treatment options for chronic hepatitis B. Replicating via an RNA intermediate, hepatitis B virus (HBV) is known to be principally vulnerable to RNAi. However, beyond delivery, the relevant issues of potential off-target effects, target site conservation in circulating HBV strains, and efficacy of RNAi itself have not systematically been

Client involvement in home care practice: a relational sociological perspective.

GLASDAM S, HENRIKSEN N, KJaeR L and PRAESTEGAARD J. Nursing Inquiry 2012 [Epub ahead of print] Client involvement in home care practice: a relational sociological perspective 'Client involvement' has been a mantra within health policies, education curricula and healthcare institutions over many years, yet very little is known about how 'client involvement' is practised in home-care services. The a

A democratic critique of precarity

The term ‘precarity’ has become increasingly popular as a way to capture the material and psychological vulnerability resulting from neoliberal economic reforms. This article demonstrates that such precarity is incompatible with democracy. More specifically, it makes two arguments. First, and inspired by Montesquieu’s analysis of ‘the principles’, or public commitments behind different forms of go