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AbstractObjectivesThe aim of this systematic review and meta-analysis was to analyse and summarize studies on the effects of polypharmacy on people living with dementia (PwD). The study aimed to categorize these effects, evaluate the quality of the studies, and estimate the pooled effect sizes of these consequences using meta-analysis.MethodA systematic literature review was conducted following th

We use high-resolution (35pc) hydrodynamical simulations of galaxy formation to investigate the relation between gas accretion and star formation in galaxies hosted by dark matter haloes of mass at. At high-redshift, cold-Accreted gas is expected to be readily available for star formation, while gas accreted in a hot mode is expected to require a longer time to cool down before being able to form

In the aftermath of the Covid-19 pandemic, the accelerated shift to remote and hybrid work modes has left many office buildings vacant. Meanwhile, many cities struggle with providing housing. Adaptive reuse (AR) is the process of giving an existing building a new life, typically through an extensive renovation and refurbishment. Residential adaptative reuse specifically refers to adapting for hous

The Rieger syndrome, an autosomal dominant disorder involving ocular, dental, and umbilical defects is caused bymutations in PITX2, a Bicoid type homeobox protein. Moreover, Pitx2 is involved in the Nodal/Sonic hedgehogpathway that determines left/right polarity. Mouse Pitx2 mRNA is expressed in eye, tooth and umbilicus consistent withthe human Riegers phenotype. It is also asymmetrically expresse

This issue of Journal of Scandinavian Cinema features a diverse range of articles covering topics from early silent cinema to contemporary genre filmmaking. Highlights include discussions of digital restoration, cinematic influence, Sámi culture, horror in children’s cinema and film literacy. The issue also reviews new research on Carl Th. Dreyer that emphasizes the emotional aspects of his films.

Background: Pediatric atopic dermatitis (AD) is a common chronic disease. For assessing treatment outcomes, the concept of controlled and uncontrolled AD has been introduced. Objectives: The aim of the study was to estimate healthcare resource use in terms of visits, treatments and costs in children with controlled and uncontrolled AD. Materials & Methods: The study utilised administrative dat

This entry reflects on the meaning and significance of playful work in contemporary organizations. In recent years, playful work has become a prominent managerial technique to combat employee disengagement and low morale in organizations. This trend has its roots in positive psychology, especially Csikszentmihalyi’s concept of flow and Deci and Ryan’s self-determination theory. Developments such a

What future aspirations have informed the incentives for producing children's literature in Muslim minority communities? What social dynamics and theological debates have accompanied its visions of Islamic futures? What narrative tropes, visual-aesthetics norms and literary genres has it appropriated, while maturing into an innovative religious-pedagogic-literary expression? Probing such questions

BACKGROUND: Acute myeloid leukemia (AML) is an aggressive hematological neoplasm. Little improvement in survival rates has been achieved over the past few decades. Necroptosis has relationship with certain types of malignancies outcomes. Here, we evaluated the diagnostic ability, prognostic capacity of necroptosis-related genes (NRGs) and the effect of their copy number variations (CNVs) in AML.ME

Intracellular delivery is crucial in biological and medical studies. Although many molecular tools have been created for cell-based gene therapies, it remains challenging to introduce external molecules into cells. As one of the most popular non-viral transfection methods, electroporation induces transient pores in the cell membrane by applying an external electric field. Unsatisfactory transfecti

Quark spin effects in e+e- annihilation to pseudoscalar and vector mesons are implemented for the first time in the pythia Monte Carlo event generator. The spin-dependent fragmentation of the string stretched between the produced quark-antiquark pair with correlated spin states is described by the string+P30 model implemented in the string fragmentation routine of pythia by using the StringSpinner

Few studies have examined the association of various types of Fe with colorectal cancer risk. The aim of this study was to investigate different forms and sources of Fe in relation to colorectal cancer risk in a Chinese population. A total of 2138 patients with colorectal cancer and 2144 sex- and age-matched (5-year interval) controls were recruited from July 2010 to November 2017. Dietary informa

This cross-over experimental study aimed to examine the effects of filled chocolate consumption on blood glucose, insulin and ghrelin levels in 20 volunteers. After a one-week run-in period, study participants consumed two chocolate-based products, the tested biscuit or water for 21 days as a morning snack. After a two-week wash-out period, participants consumed another tested food for another 21

Objectives: Decision-analytic models assessing the value of emerging Alzheimer's disease (AD) treatments are challenged by limited evidence on short-term trial outcomes and uncertainty in extrapolating long-term patient-relevant outcomes. To improve understanding and foster transparency and credibility in modeling methods, we cross-compared AD decision models in a hypothetical context of disease-m

This study aimed to explore the effect of dietary magnesium intake on breast cancer risk both directly and indirectly via its effect on inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6). This case-control study recruited 1050 case patients and 1229 control subjects. Inflammatory marker levels of 322 cases and 322 controls, randomly selected, were measured using ELISA, and data

This article examines the narratives associated with the “Shekou Model” in China’s development of the Hambantota International Port in Sri Lanka. Through a dual narrative analysis and policy evaluation approach utilizing official Chinese and Sri Lankan statements, it examines the motivations of the Chinese Communist Party and the China Merchants Group in “selling” the Shekou Model and how Sri Lank

A carbohydrate-rich diet results in hyperglycaemia and hyperinsulinaemia; it may further induce the carcinogenesis of colorectal cancer. However, epidemiological evidence among Chinese population is quite limited. The aim of this study was to investigate total carbohydrate, non-fibre carbohydrate, total fibre, starch, dietary glycaemic index (GI) and glycaemic load (GL) in relation to colorectal c

The effects of dietary vitamin D, Ca and dairy products intakes on colorectal cancer risk remain controversial. The present study investigated the association between these dietary intakes and the risk of colorectal cancer in Guangdong, China. From July 2010 to December 2018, 2380 patients with colorectal cancer and 2389 sex- and age-matched controls were recruited. Dietary intake data were collec