Safety Evaluation and Growth Optimisation of a New Probiotic
Gut microbiota play a central role in metabolism for example in blood glucose homeostasis and appetite regulation. This thesis provides a prospect of using the bacterium Prevotella copri as a probiotic to help maintain a healthy gut microbiota as many evidences points towards probiotics to have a great potential as preventative agents or therapeutics for type 2 diabetes. In the first part of the tAccording to the World Health Organization (WHO) nearly 8.5% of the global population is affected by metabolic diseases such as type 2 diabetes and obesity which are one of the major causes of death and disability worldwide. This causes a huge financial burden on the healthcare system globally. Therefore, there is an urgent need to prevent, delay and treat these diseases and their debilitating com