This study was conducted to explore treatment and disease-related effects on health-related quality of life (HRQoL) in patients with aggressive lymphoma, to identify predictors for impaired long-term HRQoL, and to analyze the prognostic value of pretreatment HRQoL. Ninety-five patients with aggressive lymphoma, constituting a subset of a randomized multicenter trial comparing CHOP and MACOP-B, ent

Kinetic properties of the monomeric enzyme dUTPase from herpes simplex virus type 1 (HSV) were investigated and compared to those previously determined for homotrimeric dUTPases of bacterial and retroviral origins. The HSV and Escherichia coli dUTPases are equally potent as catalysts towards the native substrate dUTP with a kcat/KM of about 107 M-1 s-1 and a KM of 0.3 μM. However, the viral enzyme

Since it is difficult to predict the future using the concept of strategy as options on the future introduced by Peter J. Williamson is a way of circumventing this insecurity. This study further develops this theory by introducing a process or framework for choosing the options based on scenario analysis. By using scenario analysis small glimpses of possible futures can be seen and by selecting op

The 3rd Annual EULAR Congress, held in Stockholm on 12-15 June 2002, had a turnout of 8300 delegates, almost identical to last year's record attendance level in Prague. The venue was close to ideal, allowing ample space for poster sessions in the exhibition hall. The manned poster sessions were well attended, even on the last day of the Congress. The numerous invited speakers represented the world

OBJECTIVE: To compare the outcome following Lichtenstein open mesh technique or Shouldice repair for inguinal hernia operated on by surgeons in training. DESIGN: Prospective, randomised, trial. SETTING: District hospital, Sweden. SUBJECTS: 200 men with primary inguinal hernias. INTERVENTIONS: Lichtenstein mesh repair or Shouldice repair. MAIN OUTCOME MEASURES: Duration of operation, postoperative

Popular Abstract in Swedish Gränsöverskridande luftföroreningar ger upphov till såväl allvarliga miljöproblem ( t ex försurning, övergödning och skogskador) såsom hot mot hälsan. Denna bok analyserar den roll vetenskapliga experter spelar i de pågående internationella förhandlingarna som syftar till att reducera luftföroreningsproblemen i Europa. Samspelet mellan forskare och beslutsfattare har inLong-range transboundary air pollution generates pressing environmental problems such as the acidification of lakes and soils, forest decline and loss of biodiversity as well as threats to human health across Europe. The overall aim of this study is to explore the role of scientific expertise in environmental diplomacy by analyzing recent international agreements in the transboundary air pollution

MRI and CT are modalities appropriate for liver imaging. To obtain higher sensitivity in diagnoses of focal lesions in the liver, contrast media (CM) are used. Non-specific extracellular CM are not optimal as they rapidly diffuse into both normal tissue and tumorous tissue. By two different mechanisms, the hepatobiliary route and targeting to the reticuloendothelial system, agents may accumulate i

Popular Abstract in Swedish Klassiska såväl som moderna sociologer har hävdat att moralen förlorat sin sammanhållande funktion i samhället. Medan det förmoderna samhället präglades av en betydligt mer entydig moral, som upprätthölls i ljuset av en religiös och rättslig auktoritet, har det sen- eller postmoderna samhället rört sig mot en uppluckring av det gemensamma goda. Denna förändrade samhällsVoices from within the victim movement express a need for morality to have fixed boundaries between good and evil, right and wrong. However, such a morality is not always easy to define and uphold. It is thought important to consider the victims particular experiences, through another logic and morality than the strictly legally defined. This dissertation studies victim support as a moral definiti

It has been suggested that electromagnetic fields (EMF) act as promoters late in the carcinogenesis process. To date, however, there is no convincing laboratory evidence that EMFs cause tumour promotion at non-thermal exposure levels. Therefore the effects of exposure to electromagnetic fields were investigated in a rat brain glioma model. Some of the exposures correspond to electromagnetic fields

Boken "Bibeln och Koranen" handlar om tre abrahamiriska religionerna;judendom, kristendom och islam. Författaren jämför de heliga texterna av dessa systerreligioner.

Hans Rott is well-known for his work on belief revision theory in the tradition founded by Carlos Alchourro´ n, Peter Ga¨ rdenfors and David Makinson (hereafter, ‘AGM’) to which he has contributed in a number of fine articles. One of his main achievements is the establishment of far-reaching connections between AGM-style belief revision theory and the classical theory of rational choice, as the la

The individual lifetimes of three low-lying states in the proton-decaying well-deformed rotational band in the second minimum of the N = Z nucleus Cu-58 were determined. Doppler-shift attenuated gamma -ray lineshapes were analyzed following the fusion-evaporation reaction C-40,(Mg-24,1 alpha 1p1n)Cu-58 and using the EUROBALL gamma -ray spectrometer coupled to ancillary detector systems. The deduce

BRCA1 mutations, although implicated in disease predisposition in a major part of the hereditary breast cancer population, do not seem to be crucially involved in tumorigenesis of sporadic breast and ovarian cancers. This suggests that tumours arising in BRCA1 mutation carriers may differ from BRCA1 negative hereditary and sporadic cancer in genetic and biological features, as well as in clinical

We construct hadronic potentials that describe the spectrum and decays of electromagnetic bound states of hadrons, and are consistent with Chiral Perturbation Theory. This procedure enables one to clarify the status of the calculations-based on potential models-of the electromagnetic corrections to the observables of hadronic atoms and to the strong scattering amplitudes at low energy.