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To keep the alcoholic in out-patient treatment. : A differentiated approach through treatment contracts
Eighty-two alcoholics were offered a 2-year out-patient programme characterized by stressing the patients' own decisions both in joining the programme and in the choice of objectives and methods, by repeated feedbacks through treatment evaluations, and by relapse prevention. The 58 patients who accepted were more often married than the others. All but eight completed the programme. The most import
Fructose-induced carbonyl/oxidative stress in S. Cerevisiae : Involvement of TOR
The TOR (target of rapamycin) signaling pathway first described in the budding yeast Saccharomyces cerevisiae is highly conserved in eukaryotes effector of cell growth, longevity, and stress response. TOR activation by nitrogen sources, in particular amino acids, is well studied; however its interplay with carbohydrates and carbonyl stress is poorly investigated. Fructose is a more potent glycoxid
Explosive ice multiplication by mechanical break-up in ice-ice collisions : A dynamical system-based study
Mechanical break-up in ice-ice collisions observed in the laboratory can lead to explosive ice multiplication. The possibility is examined in detail by constructing an idealized analytical single-point (zero-dimension) model assuming spatial homogeneity within a cloud. The rate of generation of primary ice is fixed at a constant value over time, corresponding to a situation in which the relative h
A generalized Sibuya distribution
The Sibuya distribution arises as the distribution of the waiting time for the first success in Bernoulli trials, where the probabilities of success are inversely proportional to the number of a trial. We study a generalization that is obtained as the distribution of the excess random variable N − k given N > k, where N has the Sibuya distribution. We summarize basic facts regarding this distribut
The health-schooling relationship: Evidence from Swedish twins
Health and education are known to be highly correlated, but the mechanisms behind the relationship are not well understood. In particular, there is sparse evidence on whether adolescent health may influence educational attainment. Using a large registry dataset of twins, including comprehensive information on health status at the age of 18 and later educational attainment, we investigate whether h
Acute-phase proteins and incidence of diabetes : a population-based cohort study
Aims: To examine the relationship between plasma levels of the acute-phase proteins ceruloplasmin, alpha-1-antitrypsin, orosomucoid, haptoglobin and C-reactive protein (CRP), and incidence of diabetes in the population-based Malmö Diet and Cancer Study—Cardiovascular Cohort (MDCS-CC). Methods: The study population consists of 4246 participants (aged 46–67 years, 60.8 % women) with no previous hist
What socioeconomic factors are associated with different levels of antenatal care visits in Bangladesh? A behavioral model
We identify the socioeconomic determinants of three levels of antenatal care (ANC) visits (no, intermediate [1–3], and recommended [≥4]) in Bangladesh using a behavior model framework for health care utilization. Using multinomial logistic regression, we found that different levels of visits had different determinants; for example, media exposure increased the likelihood of intermediate compared w
The linkage between patterns of daily occupations and occupational balance : Applications within occupational science and occupational therapy practice
Patterns of daily occupations (PDO) and occupational balance (OB) are recurring phenomena in the literature. Both are related with health and well-being, which makes them central in occupational therapy practice and occupational science. The aim was to review how PDO and OB are described in the literature, to propose a view of how the two constructs may be linked, and elaborate on how such a view
Supporting Scope Tracking and Visualization for Very Large-Scale Requirements Engineering-Utilizing FSC+, Decision Patterns, and Atomic Decision Visualizations
Deciding the optimal project scope that fulfills the needs of the most important stakeholders is challenging due to a plethora of aspects that may impact decisions. Large companies that operate in rapidly changing environments experience frequently changing customer needs which force decision makers to continuously adjust the scope of their projects. Change intensity is further fueled by fierce ma
Distributions of spatial wave size for random fields
A method of measuring three-dimensional spatialwave size is proposed and statistical distributions of the size characteristics are derived in explicit integral forms for Gaussian sea surfaces. New definitions of wave characteristics such as the crest-height, the length, the size and the wave front location are provided in fully dimensional context. The joint statistical distributions of these wave
Integrator of stress responses calmodulin binding transcription activator 1 (Camta1) Regulates miR-212/miR-132 Expression and insulin secretion
Altered microRNA profiles have been demonstrated in experimental models of type 2 diabetes, including in islets of the diabetic Goto-Kakizaki (GK) rat. Our bioinformatic analysis of conserved sequences in promoters of microRNAs, previously observed to be up-regulated in GK rat islets, revealed putative CGCG-core motifs on the promoter of the miR-212/miR-132 cluster, overexpression of which has bee
Association of knee pain and different definitions of knee osteoarthritis with health-related quality of life : A population-based cohort study in southern Sweden
Background: While the impact of knee pain and knee osteoarthritis (OA) on health-related quality of life (HRQoL) has been investigated in the literature, there is a lack of knowledge on the impact of different definitions of OA on HRQoL. The main aim of this study was to measure and compare the impact of knee OA and its different definitions on HRQoL in the general population. Methods: A random sa
How are self-rated health and diagnosed disease related to early or deferred retirement? A cross-sectional study of employees aged 55-64
Background: More people will probably continue working into old age in the future due to the increased size of aging populations in many countries. We therefore need to know more about older workers' health in relation to their work situation and retirement. This study is a part of a theoretical development of older workers' situations. Older workers' situations are theoretically themed in nine ar
Historiskt presens i nordiska bibelöversättningar
In the narrative parts of the Greek New Testament, we find instances of historical present. This article aims to show how this is reflected in the Nordic translation history. In Swedish translations of the New Testament, historical present is altogether absent, be it the early translations in the 16th century or the modern translations. The same holds true for some Danish and Faroese translations.
Cost minimization of network services with buffer and end-to-end deadline constraints
Cloud computing technology provides the means to share physical resources among multiple users and data center tenants by exposing them as virtual resources. There is a strong industrial drive to use similar technology and concepts to provide timing sensitive services. One such is virtual networking services, so called services chains, which consist of several interconnected virtual network functi
GIS-based Maps and Area Estimates of Northern Hemisphere Permafrost Extent during the Last Glacial Maximum
This study presents GIS-based estimates of permafrost extent in the northern circumpolar region during the Last Glacial Maximum (LGM), based on a review of previously published maps and compilations of field evidence in the form of ice-wedge pseudomorphs and relict sand wedges. We focus on field evidence localities in areas thought to have been located along the past southern border of permafrost.
Distributions at random events
We review the generalized Rice formula approachto deriving long-run distributions of a variety of characteristics defined at random events defined on a stochastic process. While the approach stems from the same principle originally introduced by Rice for the level crossing intensity in a random signal, we show how it generalizes to more general contexts. Firstly, we discuss events defined on rando
Efficacy and Toxicity of Intrathecal Liposomal Cytarabine in First-line Therapy of Childhood Acute Lymphoblastic Leukemia
We investigated efficacy and toxicity of replacing conventional triple (cytarabine, methotrexate, and hydrocortisone) intrathecal therapy (TIT) with liposomal cytarabine during maintenance therapy among 40 acute lymphoblastic leukemia patients. Twenty-eight of 29 patients in the TIT arm received TIT and 9/11 in the liposomal cytarabine arm received liposomal cytarabine. Arachnoiditis occurred in a