Investigating the Significance of Inflammatory Signaling in Fetal and Adult Hematopoiesis
A specific class of signaling proteins has been shown to affect adult hematopoiesis in mice, but little is known about the role that these proteins play during hematopoiesis in the fetal liver of the embryo. Here, we have studied and compared the in vitro and in vivo response to a cytokine in bone marrow and fetal liver hematopoietic stem and progenitor cells (HSPCs). We have found that fetal live