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A Novel Semi-Empirical Tire Model for Combined Slips

A new tyre-force model for simultaneous braking and cornering is presented, which is based on combining existing empirical models for pure braking and cornering with brush-model tyre mechanics. The aim is to offer an easy-to-use, accurate model for vehicle-handling simulations. On a working tyre the contact patch between the tyre and the road is, in general, divided into an adhesion region where t

Standpoint on imprinting of BCR and ABL

Cytogenetic studies of Ph-positive leukemic patients and their parents have indicated that chromosome 22 involved in the formation of the t(9;22) is of maternal origin, whereas chromosome 9 is preferentially of paternal origin. These data have suggested that the two genes BCR and ABL, which become fused through the translocation, might be imprinted, ie expressed in a parental-specific manner. Rece

Comparative cytogenetic and DNA flow cytometric analysis of 242 primary breast carcinomas

The cytogenetic and DNA flow cytometric findings in 242 breast carcinomas were compared. The combined use of both techniques improved the detection of abnormal cell populations from 65% by cytogenetic analysis alone and 59% by DNA flow cytometric analysis alone to 84%. Informative and comparable cytogenetic and flow cytometric data were obtained for 155 tumors. Among these 155 tumors, there was go

Astaxanthin-rich algal meal and vitamin C inhibit Helicobacter pylori infection in BALB/cA mice

Helicobacter pylori infection in humans is associated with chronic type B gastritis, peptic ulcer disease, and gastric carcinoma. A high intake of carotenoids and vitamin C has been proposed to prevent development of gastric malignancies. The aim of this study was to explore if the microalga Haematococcus pluvialis rich in the carotenoid astaxanthin and vitamin C can inhibit experimental H. pylori

Radiostereometric analysis in hip revision surgery--optimal time for index examination: 6 patients revised with impacted allografts and cement followed weekly for 6 weeks

We revised the hip (6 stems and 5 sockets) with impacted morselized allografts and cement in 6 patients. We followed prosthetic migration by roentgen radiostereometric analysis (RSA) every 7th day for 6 weeks after the first (index) examination performed on the first postoperative day before mobilization. Most of the migration occurred during the first 2 weeks. In most cases more than half of the

Effects of body fatness and physical activity on cardiovascular risk: risk prediction using the bioelectrical impedance method.

Aims: To explore the effects of body fat percentage (BF%) on incidence of and mortality from cardiovascular disease (CVD) and to study the cardio-protective effect of physical activity in relation to BF%. Methods: A total of 26,942 men and women, aged 45-73 years, without history of CVD were followed up for incidence of coronary events (CE), ischaemic stroke, and CVD mortality over seven years in

A Swedish study of chemoradiation in squamous cell carcinoma of the esophagus

This multicenter study describes the development of a chemoradiation protocol for the treatment of non-metastatic squamous cell carcinoma of the esophagus. Eighty patients were treated with three courses of chemotherapy (cisplatinum and 5-fluorouracil) with concomitant radiotherapy (40 Gy) during the last two courses of chemotherapy. Esophagectomy was performed, when feasible. If no operation was

Survival of full-thickness retinal xenotransplants without immunosuppression

Background: A study was carried out to explore the survival of xenogeneic full-thickness retinal transplants in the subretinal space of hosts without immunosuppression. Methods: Nine adult rabbits received a complete immature rat neuroretina in the subretinal space. No immunosuppression was given, and the animals were followed up for 15 or 34 days. The eyes were then examined histologically with h

Effects of increased solar ultraviolet-radiation on terrestrial plants

Physiological and developmental processes of plants are affected by UV-B radiation, even by the amount of UV-B in present-day sunlight. Plants also have several mechanisms to ameliorate or repair these effects and may acclimate to a certain extent to increased levels of UV-B. Nevertheless, plant growth can be directly affected by UV-B radiation. Response to UV-B also varies considerably among spec

Extended Producer Responsibility in Cleaner Production: Policy Principle to Promote Environmental Improvements of Product Systems

Popular Abstract in Swedish Produkternas miljöpåverkan har varit en av de stora nya frågorna sedan 10-15 år tillbaka. Att det uppstår betydande miljöproblem under en varas hela livscykel förstod man snart, men frågan var vad man kunde göra åt det. Jag kom att arbeta med återvinningsfrågor under senare hälften av 1980-talet. Det var också vid den tiden som förebyggande miljöskyddsstrategier börjadeThe focus of the environmental policy-making has shifted noticeably during the last decade. From having played a fairly insignificant role in the 1980s and earlier, product-related environmental problems have attracted an ever-increasing interest from policy-makers, especially in industrialised countries in North-Western Europe. Considerable attention has been devoted to the concept of extended pr

Morphine with or without a local anaesthetic for postoperative intrathecal pain treatment after selective dorsal rhizotomy in children

Selective dorsal rhizotomy is a surgical procedure with a selective division of posterior spinal nerve rootlets to treat spasticity in children. The extensive surgical procedure with multilevel laminectomies and the nerve root manipulation result in intense pain postoperatively. Two intrathecal (IT) regimes of pain treatment were compared in these children, concerning their pain relief and possibl

State-centered versus nonstate-driven organic food standardization: A comparison of the US and Sweden

Organic food standardization is an increasingly important strategy for dealing with consumer concerns about the environment, animal welfare, health, and the economic structure of food production. But the ways in which this consumer-oriented strategy is introduced, organized, and debated vary considerably across countries. In Sweden, a nongovernmental organization [KRAV (Association for Control of

Escherichia coli TolA tolerates multiple amino-acid substitutions as revealed by screening randomized variants for membrane integrity and phage receptor function

Escherichia coli TolA is a cytoplasmic membrane protein required for outer membrane integrity and the translocation of F-specific filamentous (Ff) bacteriophage DNA. Both phage infection and membrane integrity depend on several TolA interactions, e.g. those of the TolA C-terminal domain (TolAIII). Membrane integrity involves interaction with two host proteins and phage translocation requires direc