Search results

Molecular docking is a computational approach that predicts interactions between ligands and protein targets based on binding energies. In this study, the potential interactions of 1,8-cineole -one of the dominant components of Eucalyptus globulus oil- with the main protease (Mpro) and macrodomain (MacI) of SARS-CoV-2 were studied by molecular docking. Nine Mpro and four ManI structures available

Over the last decades, linguistic gender-fair forms have become increasingly used by individuals and official institutions. In the French-speaking sphere, this has led to heated discussions among politicians and other stakeholders, some of which claim that these forms render texts illegible and inaccessible to the greater public. However, the processing of gender-fair forms in reading has been the

Amelogenin, the most abundant protein in developing enamel, self-assembles into supramolecular structures that serve as templates for apatite growth. Recent studies revealed that amelogenin nanoribbons exhibit hallmark features of functional amyloids, yet the molecular mechanisms governing their formation remain incompletely understood. Here, we combine atomic force microscopy, transmission electr

The precursors, [ 35S]sulfate and [2- 3H]mannose, were used to study the biosynthesis of keratan sulfate and other oligosaccharides on proteoglycans isolated from Day 8 cultures of chick limb bud chondrocytes. After alkaline borohydride treatment, three fractions with sialic acid were separated by molecular sieve chromatography. The first contained keratan sulfate which was purified by digestion w

This paper presents a symbol time offset estimator for coherent OFDM systems. This estimator exploits both the redundancy in the cyclic prefix and the pilot symbols used for channel estimation. The estimator is robust against frequency offsets and is suitable for use in dispersive channels. We base the estimator on the ML estimator for the AWGN channel. Simulations of an example system indicate a

In the beam dynamics design and modelling of the Eu- ropean Spallation Source (ESS) Drift Tube Linac (DTL) simplified models have been used for the focusing and ac- celerating elements. Since the high current requires precise control of the beam to analyze the losses it is useful to per- form the beam dynamics simulations by using accurate field maps of the focusing and accelerating elements. In t

Reglerna som möjliggör stängning av hemsidor på internet präglas av godtycke och otydlighet. Men det behöver inte vara särskilt svårt att skapa ett nytt och rättssäkert regelverk. Här har Sveriges EU-kommissionär Cecilia Malmström en viktig roll. Frågan är om hon tar sitt ansvar, skriver politiker och nätdebattörer.

The accelerator of the European Spallation Source (ESS) will deliver 62.5 mA proton beam of 2.0 GeV onto the target, offering an unprecedented beam power of 5 MW. Since the technical design report (TDR) was published in 2013, work has continued to further optimise the accelerator design. We report on the advancements in lattice design optimisations after the TDR to improve performance and flexibil

Popular Abstract in Swedish När vi äter kolhydrater, fett, protein och andra näringsämnen sker kemiska reaktioner i kroppen som kan liknas vid dom som sker när man eldar en brasa. Vid förbränning reagerar kolhydrater med syre och bildar koldioxid och vatten. Denna förbränning frigör den energi som funnits lagrad i kolhydraterna, i brasan i form av värme, och i kroppens celler omvandlas den till keNADH:quinone oxidoreductase, or complex I, is a large, complex and poorly understood bioenergetic enzyme in the respiratory chain of living organisms. The enzyme has a conserved core structure, comprising fourteen protein subunits: Seven subunits protrude from the membrane and contain a flavin prosthetic group and eight iron-sulfur clusters that guide electrons from the oxidation of NADH towards t

In recent years, many scholars have observed increasing polarization in the distribution of labor market risk, as well as social and employment rights. This phenomenon is often referred to as labor market dualization, a process deepening the divide between privileged insiders and less fortunate outsiders. Some authors have begun to search for a possible insider-outsider divide in policy preference

Food security and environmental sustainability are increasingly threatened by the current degradative practices of the agri-food industry. To mitigate the adverse environmental impacts of the agri-food supply chain, the circular food economy has been proposed as a strategy to enhance biodiversity, improve access to nutritious foods and reduce the industry’s greenhouse gas emissions. However, progr

Large-scale restoration projects are being increasingly used to address land degradation and global climate change. While these initiatives are promising, an overemphasis on tree planting may contribute to ecological degradation and carbon loss. This thesis critically examines the AFR100 initiative in southern Africa through literature analysis and expert interviews. By integrating perspectives fr

This thesis investigates how cross-linguistic phoneme distributions of 56 fundamental oppositional concepts can reveal semantic relationships by looking into the linguistic forms of 75 genetically and areally distributed languages. Based on proposals of semantic primes (Goddard 2002), reduced Swadesh lists (Holman et al. 2008), presumed ultraconservative words (Pagel et.al. 2013), attested basic a

”Now, we become just as sporadic participants” A qualitative study experience of individual counselor’s facility A counselor at a hospital is a person who is working with the mental health of the patients. Due to today’s fast-pace society stress and other mental health problems has become more and more common which has led to a higher demand of counselor workers. Alongside the practical counseli

This study aimed to evaluate the use of Pyrotechnically Generated Aerosols in electrical fires. To represent a common starting point for these fires, a cable fire ignited by a shortcut was chosen. In order to do this in a realistic way, a new method with heating the cables from the inside was used. This study examined whether the PGA has the ability to supress a cable fire inside an electrical cab