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The kidneys are the major organs affected in diarrhea-associated hemolytic uremic syndrome (D(+)HUS). The pathophysiology of renal disease in D(+)HUS is largely the result of the interaction between bacterial virulence factors such as Shiga toxin and lipopolysaccharide and host cells in the kidney and in the blood circulation. This chapter describes in detail the current knowledge of how these bac
The consideration of patient experiences has gained significant attention in recent years as part of the broader shift toward patient-centered care. The aim of this chapter is to explore the personal experiences of individuals before and after lung transplantation, highlighting how these experiences are deeply embedded within a network of family and social connections. This chapter emphasizes the
Host-defense peptides play a fundamental role in the innate immune system by modulating inflammatory responses. Previously, it was shown that the thrombin derived host-defense peptide GKY25 inhibits LPS-induced responses of monocytes and macrophages in vitro, ex vivo, and in vivo. In this study, the effect of GKY25 on the interaction of monocytes/macrophages with Gram-negative bacteria was explore
The cluster of pathologies comprising the metabolic syndrome (MetS) includes increased waist circumference, hyperglycemia, elevated blood pressure and hyperlipidemia. With time, these conditions present a major risk of developing obesity, type 2 diabetes and atherosclerosis. Fecal microbiota transplant (FMT) experiments performed in mice have given an intriguing foundation for a microbial-based th
When discussing the relationship between religion and LGBTQIA+ rights in Europe today, the two are often framed by both religious and secular representatives as oppositional forces. While the rights of sexual and gender minorities are frequently described as symbols of progress and modernity within liberal democracies, religious communities and traditions are commonly portrayed as defenders of tra
In this paper we present the recent improvements for optically stimulated luminescence dosimetry using ordinary salt (NaCl). It is shown that the dosimetric properties of NaCl may be improved by compressing the salt grains to solid pellets. With a linear dose response in, at least, the region <100 mGy, a zero background signal (when pre-bleached) and a minimum measurable dose of 10-20 μGy and high
Wireless ad hoc networks have the last 10 years gained a lot of attention within the research community. A wireless ad hoc network is a special type of wireless network where nodes are typically mobile and doesn’t rely on any fixed infrastructure to operate correctly. Much work has been done on developing robust and stable routing algorithms that consider the dynamic nature of an ad hoc network: n
The main concern of this paper is the joint utilization of new methods of research and analysis in the study of value. 40 persons, varying from age 20 to 70 and from different professional domains were studies by the use of a three-images technique inspired by Murray´s TAT. The aim was to unveil the implicit dimensions of work related values. Three analytical methods (content analysis, lexical ana
Popular Abstract in Swedish Gastroesofageal refluxsjukdom är ett tillstånd som kännetecknas av att magsyra åker upp i matstrupen (reflux). Reflux är ett normalt fenomen som förekommer hos alla individer utan att orsaka symtom eller vävnadsskador. Hur detta normaltillstånd utvecklas till ett sjukdomstillstånd är ej helt klarlagt. Reflux förhindras normalt av en barriär vid övergången mellan matstruThere is a persisting controversy concerning the definition, etiology and pathogenesis of Barrett's esophagus. The dramatic and parallel increase in the incidence of esophageal and junctional adenocarcinoma over the past decades justifies an evaluation of the pathophysiology of premalignant metaplastic changes of the esophagus and the gastroesophageal junction. Patients were evaluated with upper G
In this thesis Word of Life (Slovo zivota) in the Czech Republic is studied from a sociological perspective with a special focus on the Swedish influence, especially the teachings of Ulf Ekman, on the Czech Word of Life-congregations. Another purpose is to examine if there also is space for domestic interpretations of the theology of the faith-movement and if there is any integration with Czech re
This thesis aimed to examine the relationship between climate and atmospheric CO2 concentrations through rapid climate changes during the Holocene. Climate was reconstructed using high-resolution, radiocarbon dated, lake sediment geochemical proxies (magnetic susceptibility, loss-on-ignition, total carbon/nitrogen/sulphur determinations and biogenic silica), vegetational reconstruction (pollen ana
Popular Abstract in Swedish Genetisk påverkan i ledgångsreumatism Ett väl fungerande immunsystem är en förutsättning för kroppens kamp mot diverse sjukdomar orsakade av t ex virus och bakterier. En grundläggande egenskap hos immunsystemet är dess förmåga att skilja på vad som är kroppens egna celler och molekyler och vad som är främmande. Ibland fungerar inte denna diskriminering som den ska och In this thesis the role of major histocompatibility complex (Mhc) class II molecules in development of autoimmune disease such as rheumatoid arthritis (RA), was studied. By combining an experimental model for RA, collagen type II induced arthritis (CIA), with molecular biology methods the importance of polymorphism in Mhc class II genes for disease development was investigated. The Mhc region con
Aims: The aim of this study was to investigate the associations between socioeconomic status (SES) and self-reported unmet health care needs, taking economic stress, generalized trust in other people and trust in the health care system into account. Methods: The 2012 public health survey in Scania was conducted using a postal questionnaire and included 28,029 participants aged 18-80 years. The stu
In this chapter, we describe the detection of Ebola virus minigenomic mRNA using a nonradioactive Northern hybridization. This protocol comprises all steps beginning with the synthesis of a digoxigenin-labeled riboprobe, harvest of transcribed mRNA from cells transfected with the Ebola virus minigenome system, separation of mRNA species by denaturing RNA gel electrophoresis, transfer of the mRNA t
Popular Abstract in Swedish Melamisufism (melamet) fanns i olika delar av Osmanska riket. Den sista perioden, då melamirörelsen var särskilt märkbar, tar sin början i slutet av 1800-talet, och då med en koncentration i den europeiska delen av det osmanska riket (Rumeli). Detta hänger samman med att melamiordens huvudschejk Sejjid Muhammed Nur el-Arebi, bodde och var verksam där under denna tid. MeThis dissertation focuses on Melami history in Bosnia with emphasis on the 20th century. The well-known Melami master Hajrullah Abdurahmanovic (d. 1965) in this study becomes an exponent for changes in the political and social role of religion in course of the 20th century. The purpose of this research is to describe and analyze the theology of the Melami movement in the environments created by su
