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Pan-kinome of Legionella expanded by a bioinformatics survey

The pathogenic Legionella bacteria are notorious for delivering numerous effector proteins into the host cell with the aim of disturbing and hijacking cellular processes for their benefit. Despite intensive studies, many effectors remain uncharacterized. Motivated by the richness of Legionella effector repertoires and their oftentimes atypical biochemistry, also by several known atypical Legionell

Religion and Forced Displacement in Georgia

This policy report focuses on religion-state relations in Georgia and argues that competition between the Eastern Orthodox Church, the Armenian Apostolic Orthodox Church and the Muslim community have had an impact on state involvement with humanitarian programmes. The Georgian case stands out as the country experienced three waves of internal forced displacement. Each wavehas shown that religious

A prehistory of violence : Evidence of violence related skull trauma in southern Sweden, 2300-1100 BCE

Warriors and warfare have become common themes within Bronze Age archaeology the past 10 -20 years. Recent reporting of Neolithic and Bronze Age massacres and battlefields in Germany supports endemic violence in these regions. But what about in southern Scandinavia? This paper explores the evidence of violence related skull trauma from a pooled sample of 257 individuals from 40 different localitie

The use of polyhydroxylated carboxylic acids and lactones to diminish biofilm formation of the pathogenic yeast : Candida albicans

The vaginal microbiome of healthy women is a diverse and dynamic system of various microorganisms. Any sudden change in microbe composition can increase the vaginal pH and thus lead to vaginal infections, conditions that affect a large percentage of women each year. The most common fungal strains involved in infections belong to the yeast species Candida albicans. The main virulence factor of C. a

Policy evaluation

In order to develop new environmental policies, it is important first to evaluate those that have already been used. However, this intuitively simple idea is difficult to apply in practice, no more so than in the complex governance context of the EU. Attributing impacts to specific policies is challenging, and making evaluations useful for political decision making is even more demanding. Five app

Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E

The botulinum neurotoxins are potent molecules that are not only responsible for the lethal paralytic disease botulism, but have also been harnessed for therapeutic uses in the treatment of an increasing number of chronic neurological and neuromuscular disorders, in addition to cosmetic applications. The toxins act at the cholinergic nerve terminals thanks to an efficient and specific mechanism of

Strategies in supporting inclusive education for autistic students : A systematic review of qualitative research results

Background and Aim: Strategies to modify and adjust the educational setting in mainstream education for autistic students are under-researched. Hence, this review aims to identify qualitative research results of adaptation and modification strategies to support inclusive education for autistic students at school and classroom levels. Method: In this systematic review, four databases were searched.

Introduction

This edited volume discusses the emergence and development, and in some cases also the disappearance, of social movements and activism in the Swedish 1980s. The introductory chapter gives the background and aim of the volume and discusses why the Swedish case is interesting from a European perspective. The 1980s have often been described as a decade when the radical social movements of the 1960s a

Introduction

There is no official or universal definition for the concept of ‘family’. The absence of EU legislative competence in the substantive family law field means that there is no ‘EU family law’. Thus it is the individual EU legal instruments in different policy areas and the jurisprudence of the Court of Justice of the EU that demarcate, on an ad-hoc basis, the contours of the concept of ‘family’ and

Heat loss to the ground from a building : slab on the ground and cellar

Heated buildings induce a heat flow from the building foundation into the ground. The topic of this thesis is the thermal process in the ground and, in particular, the heat losses from the building to the ground. Foundations of the three types slab on the ground, cellar, and crawl-space are dealt with. The crawl-space is treated in separate report. A reasonably complete theory for the thermal pro