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Deletion of a major neutralizing epitope of human papillomavirus type 16 virus-like particles.

Human papillomavirus type 16 (HPV-16) is a major cause of human cancer. Effective prophylactic vaccines are based on type-specific neutralizing antibodies. A major neutralizing epitope has been defined by the monoclonal antibody H16.V5. To investigate the importance of this epitope for overall immunogenicity of HPV-16, HPV-16 virus-like particles devoid of the H16.V5 epitope were engineered by sit

Propionibacterium acnes as an etiological agent of arthroplastic and osteosynthetic infections - Two cases with specific clinical presentation including formation of draining fistulae

This report describes two patients with orthopaedic implant infections, with specific clinical presentations including formation of draining fistulae. Propionibacterium acnes was isolated in multiple cultures in both cases. Phenotypic and genetic characterisation of the isolates clearly emphasizes the significance of P. acnes as an etiological agent of implant infections. These infections are insi

Short communication: Lactic acid bacteria from the honeybee inhibit the in vitro growth of mastitis pathogens.

Despite the increasing knowledge of prevention and control strategies, bovine mastitis remains one of the most challenging diseases in the dairy industry. This study investigated the antimicrobial activity of 13 species of lactic acid bacteria (LAB), previously isolated from the honey crop of the honeybee, on several mastitis pathogens. The viable LAB were first reintroduced into a sterilized heat

The role of input frequency in article acquisition in early child Swedish

This paper investigates patterns of article use in monolingual early child Swedish and in child-directed adult speech. Article omissions in the adult data are found to be more widespread than previously assumed, especially articleless, ‘bare’ singular count nouns (e.g. sten ‘stone’ instead of en sten ‘a stone’) and article omissions in doubly determined nominals (e.g. lilla tummen (little thumb-th