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Adolescence is a period of significant physiological changes, and likely a sensitive window to chemical exposure. Few nation-wide population-based studies of chemical body burdens in adolescents have been published. In the national dietary survey Riksmaten Adolescents (RMA) 2016–17, over 13 chemical substance groups, including elements, chlorinated/brominated/fluorinated persistent organic polluta

BACKGROUND: This is an open-label, single-arm, single-center pilot study using 7-Tesla in vivo proton magnetic resonance spectroscopy (1H MRS) to measure brain cortical glutathione concentration at baseline before and during the use of oral fumarates as a disease-modifying therapy for multiple sclerosis. The primary endpoint of this research was the change in prefrontal cortex glutathione concentr

Objectives Registries have been highlighted as means to improve quality of care. Here, we describe temporal trends in risk factors, lifestyle and preventive medication for patients after myocardial infarction (MI) registered in the quality registry Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART). D

Aims/hypothesis: Low birthweight is a risk factor for type 2 diabetes but it is unknown whether low birthweight is associated with distinct clinical characteristics at disease onset. We examined whether a lower or higher birthweight in type 2 diabetes is associated with clinically relevant characteristics at disease onset. Methods: Midwife records were traced for 6866 individuals with type 2 diabe

Purpose: Tau pathology is associated with concurrent atrophy and decreased cerebral blood flow (CBF) in Alzheimer’s disease (AD), but less is known about their temporal relationships. Our aim was therefore to investigate the association of concurrent and longitudinal tau PET with longitudinal changes in atrophy and relative CBF. Methods: We included 61 individuals from the Amsterdam Dementia Cohor

Introduction: Glycolytic activity and hypoxia are associated with poor prognosis and radiation resistance. Including both the tumor uptake of 2-deoxy-2-[18 F]-fluorodeoxyglucose (FDG) and the proposed hypoxia tracer copper(II)diacetyl-bis(N4)-methylsemithio-carbazone (Cu-ATSM) in targeted therapy planning may therefore lead to improved tumor control. In this study we analyzed the overlap between s

Introduction: Pelvic girdle pain during and after pregnancy is a major public health problem with significant daily problems for affected women and their families. There is now accumulating evidence that pregnancy-related pelvic girdle pain originates from the sacroiliac joints and the pubic symphysis as well as their extra-articular ligaments. However, the heritability of the disease remains to b

Den här uppsatsen studerar vilka upphandlingsrättsliga konsekvenser som kan uppkomma då kommuner samverkar genom kommunalförbund, samägda kommunala aktiebolag och samverkansavtal. Studier har visat att i princip alla kommuner bedriver någon form av interkommunal samverkan. När det sker ett utbyte av prestationer som har ekonomiskt värde mellan kommuner eller mellan en kommun och ett kommunalförbuThis essay explores the consequences in terms of a procurement obligation that could follow when municipalities co-operate through an association of local authorities, a joint municipal company or an inter-municipal contract. Studies have shown that almost all Swedish municipalities conduct some form of inter-municipal co-operation. When there is an exchange of goods or services of pecuniary inte

Under den gångna våren röstades ett nytt Copyrightdirektiv igenom i EU, vilket har rönt stor uppmärksamhet. Det rör sig om Europaparlamentets och rådets direktiv (EU) 2019/790 av den 17 april 2019 om upphovsrätt och närstående rättigheter på den digitala inre marknaden och om ändring av direktiven 96/9/EG och 2001/29/EG. Många hävdar att direktivet riskerar att leda till inskränkningar i yttrande-This Spring, a new Copyright Directive has been approved by the European Union, which has drawn a lot of attention. The Directive is formally known as Directive (EU) 2019/790 of the European Parliament and of the Council of 17 April 2019 on copyright and related rights in the Digital Single Market and amending Directives 96/9/EC and 2001/29/EC. Many people claim that this Directive may lead to lim

Kärnkraften har varit en kontroversiell politisk fråga i Sverige sen de första svenska kärnkraftverken för kommersiell elproduktion togs i drift under 1960 talet. Idag står kärnkraften för cirka 40 % av Sveriges totala elproduktion, men dess framtid är osäker. Trots att uppgraderingar av olika slag görs vid de befintliga reaktorerna har dessa en maximal livslängd på cirka 60 år, vilket innebär attThe characteristics of Boron Carbide (B4C) coated polyvinyltoluene scintillators with a sputtered B4C coating ranging between 200 and 1000 nm have been studied using a photomultiplier - Lanthanum Bromide detector setup with a PuBe neutron source. The raw data from the detectors was analysed by imposing a detector coincidence condition. The coated scintillators have been compared with a commercial

Tränar du? Behöver du tips på goda och näringsrika mellanmål? Två mellanmål är utvecklade för dig som tränar och behöver få i dig bra näring. De är syrade havrebaser som innehåller -glukaner. Båda mellanmålen påvisar potentiella probiotiska och prebiotiska egenskaper. I detta projekt har två mellanmål med atleter som målgrupp utvecklats. Mellanmålen är mjölksyrade havrebaser och skillnaden melThis master thesis aims to develop a fermented “in-between-meal” snack with a macronutrient composition reflecting the needs of athletes. An oat base, enriched with whey protein, vegetable oils, salt and maltodextrin, called “Skaka & Smaka” was given as a starting product. The oat base was subjected to eight commercially available starter cultures and their fermentation profiles in the oat bas

Under 1900-talet har stormskador på skog ökat vilket är en konsekvens av vårt skogsbruk, en ökad volym av skog, och äldre skogsbestånd. Denna ökning av stormskador har konsekvenser för ekonomi, infrastruktur, skogsägare och samhälle. Samtidigt ändras klimatet successivt, och detta kommer i framtiden att innebära högre temperaturer och ökad nederbörd. Långsamt närmar vi oss ett nytt slags klimat, sDuring the 20th century storm damage in Sweden has increased as a consequence of how the forest has been managed, an increased proportion of forest and older tree stands. The increase of storm damage has consequences for the regional economy, infrastructure, foresters, and the society. At the same time the climate is gradually changing, which means increased temperatures and higher precipitation r

Katalysatorer påskyndar en reaktion utan att själva förbrukas; denna mening känner nog många igen från sin skoltid. Andra har hört talas om katalysatorer som något de "har i bilen". Mycket riktigt är det främst i bilar där vi i våra vardagliga liv stöter på katalysatorer. Här används de för att omvandla de mycket giftiga gaserna kolmonoxid och kväveoxid till för människorna ofarligt kvävIn order to fully understand the underlying processes of catalysis, it is vital to combine measurements of the catalyst surface, where the reaction occurs, with measurements of the gas concentration close to the catalyst. We have developed a convenient setup, which uses a single laser system to visualise the gas surrounding a working catalyst in situ at realistic operating conditions. Planar Lase

Det är viktigt att arbeta förebyggande för att förhindra att sexualbrott mot barn begås, inte minst eftersom sexualbrott kan få långtgående konsekvenser för den som blir utsatt. I Europarådets konvention om skydd för barn mot sexuell exploatering och sexuella övergrepp anges att varje part ska säkerställa eller främja effektiva förebyggande eller behandlande program eller åtgärder i syfte att förhPreventing sexual crimes against children is of great importance, not least due to the far-reaching consequences that sexual crimes can lead to for those who are exposed. The Council of Europe Convention on the Protection of Children against Sexual Exploitation and Sexual Abuse states that each party shall ensure or promote effective intervention programmes or measures with a view to preventing an

The purpose of this thesis is to investigate an alternative way of management within physical systems engineering development (PSED), a term which represents all fields of engineering where physical components are involved. More specifically, analysing how agile methodologies can be applicable with the use of technological advancements to overcome the restrictions hindering the increase of efficie

Author: Suzanna Falck and Pernilla Wagland Title: Between discretion and rules - First-line managers' views on the possibility to influence. [translated title] Supervisor: Karin Kullberg Assessor: Christina Erneling The aim of our study was to examine how the relationship between rules and discretion was seen by first-line managers in the municipal eldercare. What interested us was what discr

To stay within our planet’s limits and reach the United Nation’s Sustainable Development Goals, there is an urgent need to rethink our current and dominant systems. This thesis focuses on the food system, in particular, and explores how an overarching turnaround in the way we produce and consume food has the potential to trigger and steer a greater transition towards sustainability. However, this

Uppsatsen innebär ett försök att utreda MER och AMA:s förhållande till AB 04 och hur de spelar in vid fastställande av entreprenadens omfattning. För att utreda frågeställningarna har en rättsdogmatisk metod använts. Den svenska entreprenadrätten har sedan lång tid setts som definierad av standardavtalen Allmänna bestämmelser. I Allmänna bestämmelser anges att entreprenadrättsligatvister ska lösaThe thesis involves an attempt to investigate MER and AMAS’s relationship with AB 04 and which role they play in determining the scope of the contract. The thesis determines the applicable law by using the legal dogmatic method. Swedish construction contract law has for a long period of time been defined by the use of a standard form contract called AB 04. Swedish construction contract law is a d