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Analysis of vitamin D and its metabolites in biological samples – Part I : Optimization and comparison of UHPSFC-MS/MS and UHPLC-MS/MS methods

Fat-soluble vitamin D is an essential bioactive compound important for human health. Insufficient vitamin D levels can result not only in bone disease but also in other disorders, such as cancer, metabolic disorders, and diseases related to poor immune function. The current methods commonly used for vitamin D analysis are often applied to determine the levels of the most abundant metabolite in pla

Framing the Problem: Knowledge Brokers in the Multiple Streams Approach

A lot of attention has been focused on the policy stream of the multiple streams framework (MSF). John Kingdon used the role of the policy entrepreneur to theorize what was going on when problems become political issues. In order to fully grasp this process we need to further theorize also the problem stream. What is going on in the problem stream is defining the conditions for coupling done by po

Automated actual evapotranspiration estimation : Hybrid model of a novel attention based U-Net and metaheuristic optimization algorithms

Actual evapotranspiration (ETa) plays a crucial role in the water and energy cycles of the earth. An accurate estimate of the ETa is essential for management of the water resources, agriculture, and irrigation, as well as research on atmospheric variations. Despite the importance of accurate ETa values, estimating and mapping them remains challenging due to the physical and biological complexity o

Förändringar i tillförselpotential av långsiktigt hållbar skogsbiomassa

Bioenergi spelar idag en stor roll i det svenska energisystemet ur klimat- och energisäkerhetssynpunkt men vilken roll kan inhemsk bioenergi komma att spela framöver för att Sverige ska bli ett fossilfritt samhälle med nettonollutsläpp 2050? Syftet med denna rapport är att utifrån olika perspektiv beskriva hur tillförseln av inhemska skogsbaserade biobränslen kan komma att förändras under perioden

On sensory feedback in hand prostheses

Popular Abstract in Swedish Denna avhandling behandlar ämnet känselåterkoppling i handproteser. Att mista sin hand är en traumatisk upplevelse och den som har mist sin hand förlorar både känsel och motorik. En rudimentär greppfunktion kan återskapas genom att använda en handprotes. Nya och avancerade proteser som kontrolleras med hjälp av muskelsignaler finns numera på marknaden och dessa myoelektAmputation of the hand implies the loss of the ability to grasp and the ability to "feel". The grasping function can be primitively restored using an active prosthesis. Multi­articulating electrically powered hands have recently made their way to the market and these hands provide enhanced grasping and gripping capabilities. However, these hands provide no direct and conscious sensory feedback to

Potentialbedömning och kvantitativ scenarioanalys av minskade växthusgasutsläpp från svenskt jordbruk

Denna rapport utgör ett underlag till Klimatpolitiska rådets rapport 2025 som innehåller en fördjupande analys av jordbrukets potentiella bidrag till klimatmålen. Klimatpolitiska rådets rapport presenterar bland annat en analys av olika scenarier av möjliga utvecklingsvägar för svenskt jordbruk.Fokus i analysen är vad de olika scenarierna kan innebära för möjligheten till minskade växthusgasutsläp

An Analysis of Contemporary Manga Culture in Japan and Sweden with a study of the works of Naoki Urasawa

This thesis is an analysis of contemporary Manga Culture in Japan and Sweden. The objective of the study was to identify the potential and problems for Manga culture and its future in the international market. Also I try to examine the potential of Manga to establish its academic status. This research will be based on the analysis of the transition and features of Manga related with Japanese cultu

Laglotten i modern tid

Laglotten regleras i ärvdabalken (1958:637) 7 kap. 1 § och fungerar som ett arvsrättsligt skydd till förmån för bröstarvingar. Skyddet aktualiseras i de fall då en avliden valt att testamentera bort all kvarlåtenskap. Bröstarvingar har i dessa fall en lagstadgad rätt till hälften av den dödes arvslott. Laglottsregleringen infördes år 1857, men har som institut funnits betydligt längre inom svensThe statutory share of inheritance is regulated by the inheritance code (1958:637) 7 chap. 1 § and work as a protection for the forced heir to secure its right for inheritance. The protection is activated in those cases where a deceased person has chosen to not give any of the properties left to a forced heir. In these cases, the statutory share of inheritance gives the forced heir the right to a

Unlocking the Potential of Sustainability in SMEs within the Pharmaceutical Industry: The Role of Managers in Fostering Sustainability for Organizational Long-term Success

Sustainable development requires companies to do their part. Managers are central to the partaking of sustainability in their organizations, having responsibility towards internal and external stakeholders to ensure the organization's long-term survival while being mindful of other things than maximizing profit. SMEs face additional challenges than their multinational counterparts making it mo

Gene therapy by enzyme replacement for Parkinson’s disease Optimization of continuous DOPA delivery and development of a candidate vector for clinical application

The introduction of L-DOPA pharmacotherapy revolutionized the treatment of Parkinson’s disease close to fifty years ago. Before the discovery of dopamine as a neurotransmitter and its involvement in the disease, these patients had very little aid from medication and were bound to a life without movement. The dopamine neurons in the midbrain are a key player in the circuitry that is responsible for

Med samarbete i sikte : Om samordnade insatser och samlokaliserade familjecentraler

Popular Abstract in Swedish Samarbete är ett värdeladdat ord i svenskt välfärdsarbete och inom socialt arbete förespråkas samarbete ofta som något värdefullt och nödvändigt. Idag finns det en stor, om än fragmenterad, vardagskunskap om samarbete och samverkan. Vetandet präglas dock av ett okritiskt accepterande av samarbetets fördelar, samtidigt som många verksamheter visar att resultaten av samarCo-operation is highly valued in Swedish welfare work and joint efforts within and between healthcare and welfare organizations is not new in Sweden. For decades the authorities have been trying to organize and coordinate various social and medical efforts in the public sector at a central level. This thesis is focusing on the meaning of co-operation between professionals belonging to different or

Present and potential future recycling of critical metals in WEEE

This report focuses on critical metals in Waste from Electrical Electronic Equipment (WEEE) and their recycling possibilities. The criticality is defined in terms of demand. The EU needs access to these metals and recycling can be an important part of the supply-strategy. The report covers assessments of (1) the potential amount of critical metals in the selected product groups, and (2) the actual

Jordbruk

I Skåne kan klimatförändringarna förbättra förutsättningarna för produktion av grödor och annan biomassa via förlängd växtsäsong och ökad tillväxt. Samtidigt ökar dock risker för skador, sjukdomar och insektsangrepp. En intensifiering av jordbruk för att ta vara på ökad produktionspotential och för att möta ett ökat behov av biomassa riskerar att förvärra problem som redan finns när det gäller fö

Through the eyes of a woodpecker: Understanding habitat selection, territory quality and reproductive decisions from individual behaviour

Popular Abstract in Swedish Med hackspettsögon: att förstå habitatval, revirkvalitet och reproduktionsbeslut utifrån individers beteende Min doktorsavhandling bygger både på teoretiska modeller och på fältstudier av mindre hackspett (Dendrocopos minor). För att slippa språkliga krumbukter eller tvetydigheter kommer jag hädanefter att kalla arten "småspett" i denna sammanfattning. Fältstudierna gjIn this thesis I present some connections between foraging behaviour and reproductive success, time budget, tree species use, and habitat selection. The thesis is based upon both theoretical and empirical work. All empirical studies concern a south Swedish population of lesser spotted woodpeckers Dendrocopos minor, studied between 1990 and 1996. The foraging behaviour of the lesser spotted woodpe

A triangular form-based multiple flow algorithm to estimate overland flow distribution and accumulation on a digital elevation model

In this study, we present a newly developed method for the estimation of surface flow paths on a digital elevation model (DEM). The objective is to use a form-based algorithm, analyzing flow over single cells by dividing them into eight triangular facets and to estimate the surface flow paths on a raster DEM. For each cell on a gridded DEM, the triangular form-based multiple flow algorithm (TFM) w

The breath of life - Womens' experiences of breathing adapted radiation therapy.

PURPOSE: To describe and analyze how women with breast cancer experience breathing adapted radiation therapy (BART) and to explore how women manage daily radiation therapy. METHOD: Individual interviews were conducted with 20 women treated with BART for breast cancer concerning their perception of radiation therapy. The transcribed interviews were analyzed using qualitative content analysis. RESUL

Participatory modelling for the integrated sustainability assessment of water: The World Cellular Model and the MATISSE project

This paper describes the participatory process of developing and implementing a prototype model aimed at supporting the Integrated Sustainability Assessment of water resources and policy options at different scales. The model - called the World Cellular Model (WCM) focuses on the representation of agents’ behaviours and their systemic relationships with their environment. This is achieved by exami