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Genetic anticipation in Swedish Lynch syndrome families

Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS) caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have an earlier onset compared to the general population. However, age at first primary cancer varies wit

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

Aims/hypothesis: During the A/H1N1 2009 (A/California/04/2009) pandemic, mass vaccination with a squalene-containing vaccine, Pandemrix®, was performed in Sweden and Finland. The vaccination was found to cause narcolepsy in children and young adults with the HLA-DQ 6.2 haplotype. The aim of this study was to investigate if exposure to Pandemrix® similarly increased the risk of islet autoimmunity o

Tumor Necrosis Factor Receptor 1 and 2 Are Associated With Risk of Intracerebral Hemorrhage

BACKGROUND AND PURPOSE: Raised plasma concentrations of tumor necrosis factor receptors (TNFR) have been linked to arterial stiffness, cerebral microbleeds, and vascular events. The aim of this study was to investigate the association of circulating levels of TNFR1 and TNFR2 with risk for future intracerebral hemorrhage (ICH).METHODS: The population-based MDCS cohort (Malmö Diet and Cancer Study;

Auditory Brainstem Response (ABR) and Cambridge Neuropsychological Test Automated Battery (CANTAB) as Objective Support in Diagnosing Childhood ADHD and ASD

AbstractBackgroundThere is a need for easily administered objective tests in neurodevelopmental disorders. We investigated the clinical utility for child and adolescent psychiatry of Auditory Brainstem Response (ABR) and Cambridge Neuropsychological Test Automated Battery (CANTAB) as support in diagnosing attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). MethodsTh

The economic burden of human papillomavirus-related precancers and cancers in Sweden

High-risk (HR) human papillomavirus (HPV) infection is an established cause of malignant disease. We used a societal perspective to estimate the cost of HR HPV-related cervical, vulvar, vaginal, anal, and penile precancer and cancer, and oropharyngeal cancer in Sweden in 2006, 1 year before HPV vaccination became available in the country. Materials and methods This prevalence-based cost-of-illness

No improvement in injection frequency or in visual outcome over time in two cohorts of patients from the same swedish county treated for wet age-related macular degeneration

Background: Although ranibizumab has been used for the treatment of wet age-related macular degeneration (AMD) since 2007, real-world studies still report undertreatment resulting in a less favorable visual outcome. In this study, two different time cohorts of patients treated with ranibizumab for wet AMD in routine care were analyzed to observe whether there was a change over time regarding visua

Maternal cancer and congenital anomalies in children ± a Danish nationwide cohort study

Several studies on pregnancy-Associated cancers have suggested an association with congenital anomalies in offspring. Previous studies have included maternal cancers diagnosed up to 2 years after pregnancy; however, long latency periods of some cancers mean that cancers diagnosed many years postpartum might have been present during pregnancy in a preclinical state. This paper considers the associa

Tracking the picosecond deactivation dynamics of a photoexcited iron carbene complex by time-resolved X-ray scattering

Recent years have seen the development of new iron-centered N-heterocyclic carbene (NHC) complexes for solar energy applications. Compared to typical ligand systems, the NHC ligands provide Fe complexes with longer-lived metal-to-ligand charge transfer (MLCT) states. This increased lifetime is ascribed to strong ligand field splitting provided by the NHC ligands that raises the energy levels of th

Epidemiology and clinical manifestations of Lyme borreliosis.

Popular Abstract in Swedish Det har nu gått 20 år sedan ett utbrott av ledinflammation (arthrit), i Connecticut, USA, satte forskarna på spåret till den sjukdomsbild som vi idag kallar fästingöverförd borreliainfektion och det är snart 15 år sedan man lyckades isolera bakterien som orsakar sjukdomen, Borrelia burgdorferi. Symptomen på sjukdomen har visserligen varit kända sedan sekelskiftet men he

Option Pricing and Bayesian Learning

Popular Abstract in Swedish En europeisk köpoption ger innehavaren rätten, men inte skyldigheten, att köpa en underliggande tillgång till ett visst pris, lösenpriset, vid ett bestämt datum, lösendagen. En europeisk säljoption definieras på motsvarande sätt: den ger innehavaren rätten, men inte skyldigheten att sälja den underliggande tillgången. En teori för hur denna typ av finansiella kontrakt sThis thesis consists of three chapters devoted to both empirical and theoretical aspects of option pricing. The first chapter investigates the market for European options on the Swedish OMX index using daily data for the period 1993-2000. The assumption of constant volatility of the returns underlying the Black and Scholes option pricing formula is assessed by extracting the volatilities implied

Vasoactive Peptides with Angiogenesis-Regulating Activity Predict Cancer Risk in Males.

BACKGROUND: Tumor development requires angiogenesis, and antiangiogenesis has been introduced in the treatment of cancer patients; however, how the cardiovascular phenotype correlates with cancer risk remains ill-defined. Here, we hypothesized that vasoactive peptides previously implicated in angiogenesis regulation predict long-term cancer risk.METHODS: We measured midregional proatrial natriuret

Incidence and characteristics of distal radius fractures in a southern Swedish region

BACKGROUND: The incidence of distal radius fracture has increased substantially during the last 50 years according to several studies that estimated the overall incidence in various general populations. The incidence of fracture classified according to severity has not been well documented. The aim of this population-based study was to estimate the overall and type-specific incidence rates of dist

X-Stop Versus Decompressive Surgery For Lumbar Neurogenic Intermittent Claudication: A Randomized Controlled Trial With 2 Years Follow-Up.

ABSTRACT: Study Design. Prospective randomized controlled study.Objective. To compare the outcome of indirect decompression by means of the X-Stop implant to conventional decompression in patients with neurogenic intermittent claudication due to lumbar spinal stenosis.Summary of Background Data. Decompression is the golden standard for lumbar spinal stenosis nowadays but afflicted with complicatio

Effect of Type 2 Diabetes Predisposing Genetic Variants on Colorectal Cancer Risk.

Background: The link between colorectal cancer (CRC) and type 2 diabetes mellitus (T2D) has been extensively studied. Although it is commonly accepted that T2D is a risk factor for CRC, the underlying mechanisms are still poorly understood. Research Design and Methods:Given that the genetic background contributes to both traits, it is conceivable that genetic variants associated with T2D may also

General syllabus for third cycle studies in visual arts 170531 0

Brevmall Faculty of Fine and Performing Arts, Malmö General Syllabus for Third Cycle Studies in Visual Arts leading to a Degree of Doctor of Philosophy in Fine Arts 1. Programme details Programme and specialisation: Third cycle studies in Visual Arts Code: KOKOFK01 Credits: 240 Cycle: Third Degree title in English: Doctor of Philosophy in Fine Arts in Visual Arts Degree Title in Swedish: Konstnärl

https://www.arts.lu.se/sites/arts.lu.se/files/general_syllabus_for_third_cycle_studies_in_visual_arts_170531_0.pdf - 2026-05-06

Abstract volume mmv 2016

May 16–20, 2016 Museum of Evolution, Uppsala University Uppsala, Sweden Program and Abstracts Benjamin P. Kear, Johan Lindgren & Sven Sachs, Editors 5th Triennial Mosasaur Meeting – a global perspective on Mesozoic marine amniotes May 16–20, 2016 Museum of Evolution, Uppsala University Uppsala, Sweden Schedule of Meeting Events TUESDAY MORNING, MAY 17, 2016 TECHNICAL SESSION I, 10:30–12:00 Moderat

https://www.geology.lu.se/sites/geology.lu.se/files/abstract_volume_mmv_2016.pdf - 2026-05-06

KONT25 Matrix, Mater, Matter

KONT25 Matrix, Mater, Matter, Materiality, Materialism, New Materialism, Old Materialism... Lund University Faculty of Fine & Performing Arts KONT25, Matrix, Mater, Matter, Materiality, Materialism, New Materialism, Old Materialism..., 15 credits Matrix, Mater, materia, materialitet, materialism, ny materialism, gammal materialism..., 15 högskolepoäng Second Cycle / Avancerad nivå Details of appro

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/2022-11/KONT25%20Matrix,%20Mater,%20Matter.pdf - 2026-05-06