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A 5GHz 90-nm CMOS all digital phase-locked loop

An all digital phase-locked loop (ADPLL) has been implemented in a 90-nm CMOS process. It uses a phase frequency detector (PFD) connected to two time-to-digital converters (TDC). To save power the TDCs use uneven delay time in the delay line cells. An automatic tuning bank controller selects active bank of the digitally controlled oscillator (DCO), which features three separate tuning banks. The P

On observation distributions for state space models of population survey data.

1. State space models are starting to replace more simple time series models in analyses of temporal dynamics of populations that are not perfectly censused. By simultaneously modelling both the dynamics and the observations, consistent estimates of population dynamical parameters may be obtained. For many data sets, the distribution of observation errors is unknown and error models typically chos

Radiation tolerance in the eutardigrade Richtersius coronifer

Purpose: Tardigrades have a reputation of being extremely tolerant to extreme environmental conditions including tolerance to ionizing radiation while in a desiccated, anhydrobiotic state. However, the evidence for radio-tolerance in tardigrades is based on only one previous report, and there is an obvious need for complementary studies. In this paper we report an investigation on radio-tolerance

Systematic investigation of projectile fragmentation using beams of unstable B and C isotopes

Background: Models describing nuclear fragmentation and fragmentation fission deliver important input for planning nuclear physics experiments and future radioactive ion beam facilities. These models are usually benchmarked against data from stable beam experiments. In the future, two-step fragmentation reactions with exotic nuclei as stepping stones are a promising tool for reaching the most neut

Body mass index and suicide methods

Overweight and obesity is associated with lower rates of suicide. However, little is known about the association with different suicide methods. We studied the association between groups of body mass index and suicide methods. We identified all medicolegal autopsy cases with a cause of death due to external causes in Sweden during 1999-2013 (N = 39,368) and included 11,715 suicides and 13,316 acci

Cognitive and functional changes associated with Aβ pathology and the progression to mild cognitive impairment

Cognitively-normal people with evidence of β-amyloid (Aβ) pathology and subtle cognitive dysfunction are believed to be at high risk for progression to mild cognitive impairment due to Alzheimer's disease (AD). Clinical trials in later stages of AD typically include a coprimary endpoint to demonstrate efficacy on both cognitive and functional assessments. Recent trials focus on cognitively-normal

Familial occurrence of hematologic malignancies and other diseases in multiple myeloma : a case-control study

In a population-based case-control study in Sweden on multiple myeloma, the occurrence of different diseases in relatives, particularly hematologic malignancies and different types of cancer, was investigated. Through a questionnaire mailed to all living subjects, i.e. cases and controls, and to the next-of-kin for deceased subjects, information was obtained on malignant and certain other diseases

Geo-mapping of COVID-19 Risk Correlates Across Districts and Parliamentary Constituencies in India

In the current stage of the COVID-19 pandemic, as countries open up after an extended period of lockdown, it is important to assure the population that their health is not being sacrificed. In this article, we develop a geomapping approach to identify high-risk areas by considering four nonclinical risk correlates for COVID-19. These are population density, percentage of the population that is exp

Cause of death and significant disease found at autopsy

The use of clinical autopsy has been in decline for many years throughout healthcare systems of developed countries despite studies showing substantial discrepancies between autopsy results and pre-mortal clinical diagnoses. We conducted a study to evaluate over time the use and results of clinical autopsies in Sweden. We reviewed the autopsy reports and autopsy referrals of 2410 adult (age > 17)

Prevalence of dementia subtypes: A 30-year retrospective survey of neuropathological reports.

We investigated the distribution of neuropathologically defined dementia subtypes among individuals with dementia disorder. The neuropathological reports were studied on all patients (n=524; 55.3% females; median age 80, range 39-102 years) with clinically diagnosed dementia disorder who underwent complete autopsy including neuropathological examination within the Department of Pathology at the Un

Use and definitions of perioperative mortality rates in low-income and middle-income countries : a systematic review

BACKGROUND: Aggregate and risk-stratified perioperative mortality rates (POMR) are well-documented in high-income countries where surgical databases are common. In many low-income and middle-income country (LMIC) settings, such data are unavailable, compromising efforts to understand and improve surgical outcomes. We undertook a systematic review to determine how POMR is used and defined in LMICs

Occupational risk of SARS-CoV-2 infection : a nationwide register-based study of the Danish workforce during the COVID-19 pandemic, 2020-2021

OBJECTIVE: Most earlier studies on occupational risk of COVID-19 covering the entire workforce are based on relatively rare outcomes such as hospital admission and mortality. This study examines the incidence of SARS-CoV-2 infection by occupational group based on real-time PCR (RT-PCR) tests.METHODS: The cohort includes 2.4 million Danish employees, 20-69 years of age. All data were retrieved from

Low prevalence of ideal cardiovascular health in the general Swedish population : Results from the Swedish CArdioPulmonary bioImage Study (SCAPIS)

The aim of the current study was to examine the prevalence of ideal cardiovascular health (iCVH) in the general Swedish middle-aged population. To address this aim, we utilised data from the Swedish CArdioPulmonary bioImage Study (SCAPIS) which is a large Swedish population-based study (N=30,154) that combined comprehensive state-of-the-art imaging technology with clinical examinations and include

Self-compassion hos barn

Self-compassion has not yet been studied in younger children. The aim of this study was to explore self-compassion in children between 10-13 years of age and examine how self-compassion is related to well-being and social perspective-taking. In addition we wanted to explore possible age or sex differences in self-compassion. The participants consisted of 228 children from two elementary schools in

Umgängessabotage och umgängesrätt - En studie om vad som krävs för en umgängesöverflyttning

Syftet med förevarande uppsats är att belysa umgängessabotage och dess eventuella konsekvenser. Närmare bestämt avses att undersöka hur ett eventuellt umgängessabotage påverkar tingsrätten i sin bedömning när den har att ta ställning till vad som innebär barnets bästa (se föräldrabalken 6 kap. 2 a §). Umgängesrätten har utvecklats från att vara en rättighet avsedd för den förälder som utan grund hThe purpose of this essay is to highlight the consequences of the situation where one parent without acceptable cause refuses the other parent’s right of access with their child, hereinafter called ‘access sabotage’. The purpose is more specifically to investigate how the situation of access sabotage is affecting the district court in its assessment when it has to consider what outcome will be in

Oaktsamhet i fråga om ålder vid köp av sexuell handling av barn

Lagstiftaren har gjort bedömningen att barn i åldrarna 15-17 år bör skyddas från vissa sexuella handlingar och därför har man kriminaliserat köp av sexuell handling av barn. För att ansvar ska kunna utkrävas måste gärningspersonen ha uppsåt ifråga om alla omständigheter utom barnets ålder, där måste denne endast agerat oaktsamt. Enligt 6:13 BrB kan en person dömas för köp av sexuell handling av ba

Negativ rättskraft i dispositiva tvistemål - "Behovet av en klar och lättillämpad regel"

Reglerna och läran om rättskraften är ett av de mest omdiskuterade ämnena inom svensk civilprocessrätt. Det råder ett systematiskt samband mellan RB 17:11 och 13:3 som är av vikt för att förstå gällande rätt. Förståelsen för rättskraftsläran och gällande rätt kompliceras dock av ett antal rättsfall. Kontentan av praxis är att vissa alternativa yrkanden prekluderas av domens rättskraft och det kan The concept of res judicata is an intensively discussed area in Swedish civil procedural law. There is a fundamental correlation of legal and systematic importance between article 11 in chapter 17 and article 3 in chapter 13 in the Swedish Code of Judicial Procedure (RB 17:11, 13:3). However, it should be noted that the case law has complicated the understanding of the concept. This has, amongst o

Kognitiva funktionella aktiviteter vid lindrig kognitiv svikt, före och efter träningsintervention, enligt formuläret FUnctional Activities Questionnaire

Kognitiva funktionella aktiviteter vid lindrig kognitiv svikt, före och efter träningsintervention, enligt formuläret Functional Activities Questionnaire. Bakgrund: Idag lider många av mild kognitiv svikt (MCI). Tillståndet kan påverka flera kognitiva funktioner och därmed ha en inverkan på det dagliga livet. I nuläget finns ingen behandling men tidigare studier har visat att träning kan ha en p

Rättvisa – ett lotteri med höga insatser? - Om betydelsen av åklagares åtalsprövning för målsägandens förutsebara tillgång till upprättelse

Brotten vållande till kroppsskada eller sjukdom, förtal, förolämpning och egenmäktighet med barn är alla brott mot person för vilka de brottsutredande myndigheterna enbart får fatta lagföringsbeslut om åtal kan anses påkallat ur allmän synpunkt. Begränsningen, som i vissa fall enbart aktualiseras om målsäganden angivit brottet till åtal, innebär att myndigheterna inte får hantera alla fall även omThe offences causing bodily injury or illness, defamation, insulting behaviour and arbitrary conduct concerning a child are offences against the person to which the investigating authorities can take conviction decisions only if prosecution is called for in the public interest. The limitation, which in some cases is applicable only if the plaintiff has reported an offence for prosecution, means th

Frihet, jämlikhet, familjerätt - En studie av regnbågsfamiljens utveckling och koherensen mellan skilda lagstiftningar

Dagens familjer ser inte ut på samma sätt som de gjorde ”förr i tiden”, då kärnfamiljen med mamma, pappa och biologiska barn var den enda socialt accepterade familjekonstellationen. Sedan dess har stora förändringar skett hos den svenska befolkningen, som kämpat för bland annat kvinnlig frigörelse och mot patriarkala strukturer och normer. I dag erkänner det svenska rättssystemet ett flertal andraWe live in a time where one can form a family in numerous ways. A time where the nuclear family is no longer the only accepted option in our society. The movement towards women’s rights and equality, as well as the fight against patriarchal and normative structures has led to the acknowledgement of other types of families. New structures however, require new legislation. Today same-sexed marriage