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Site of action of endogenous endothelium-derived nitric oxide and of exogenous endothelin-1 along the vascular bed of skeletal muscle in vivo

No difference between daily and weekly pin site care

Energy partitioning between latent and sensible heat flux during the warm season at FLUXNET sites

Hässleberga – a Late Palaeolithic kill site in Scania, Sweden, confirmed by analysis of bone modifications

Late glacial skeletal remains from mainly reindeer and wild horse, but also other species such as mountain hare, arctic fox and elk have been collected from kettle holes in Hässleberga, Scania. Bones from reindeer and wild horse have been radiocarbon dated to Allerød and Younger Dryas. Analysis of bone modifications has revealed several different actors and factors behind the accumulation of the s

New excavations at the central site of Uppåkra, in the very south of Sweden

BVOC ecosystem flux measurements at a high latitude wetland site

A novel mutation on the transferrin gene abolishes one N-glycosylation site and alters the pattern of transferrin isoforms, mimicking that observed after excessive alcohol consumption.

In the process of obtaining a driver's license, a healthy 28year old man presented increased levels of disialo-transferrin (TF) (approx. 20%, ref. value<2) by HPLC analysis of TF isoforms (%CDT), while other markers of excessive alcohol consumption (PEth, MCV and γ-GT) were in the normal range. The objective of this study was to determine the cause of the increased %CDT levels.

Some anticonvulsants interact with the GABA receptor-ionophore complex at barbiturate/picrotoxin receptor sites

Convulsant and anticonvulsant drug binding sites related to GABA-regulated chloride ion channels.

Southern travelling habits with special reference to tumour site in Swedish melanoma patients

Southern travelling habits were recorded for 127 melanoma patients from southern parts of Sweden (the 56th latitude), 55 thyroid cancer patients, 100 non-Hodgkin's patients and 794 healthy controls from the same region. Melanoma patients were found to travel significantly more often south of the 45th latitude, as compared with patients with non-Hodgkin's lymphoma or thyroid carcinoma (RR = 2.2 for

Use of chlorhexidine on pin sites

Towards an integrated age-model for the International Ocean Discovery Program (IODP) Expedition 347 Site M0059, Little Belt

Synthesis of Double-Modified Xyloside Analogues for Probing the β4GalT7 Active Site

Monosubstituted naphthoxylosides have been shown to function as substrates for, and inhibitors of, the enzyme β4GalT7, a key enzyme in the biosynthetic pathway leading to glycosaminoglycans and proteoglycans. In this article, we explore the synthesis of 16 xyloside analogues, modified at two different positions, as well as their function as inhibitors of and/or substrates for the enzyme. Seemingly

Shortcoming in current practice of decision-making in contaminated site remediation

3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3

The galectins are a family of galactose-binding proteins playing key roles in inflammatory processes and cancer. However, they are structurally very closely related, and discovery of highly selective inhibitors is challenging. In this work, we report the design of novel inhibitors binding to a subsite unique to galectin-3, which confers both high selectivity and affinity towards galectin-3. Olefin

Mapping of the H-kininogen binding site exposed by the prekallikrein heavy chain

Ultrasonography in psoriatic arthritis: Which sites should we scan?

Decoration of bone and antler artefacts as an indication of Mesolithic networks : Finds from a central Swedish late Mesolithic site

Generation of new enzyme inhibitors using imprinted binding sites : The anti-idiotypic approach, a step toward the next generation of molecular imprinting

Synthesis and SAR Studies of Antibacterial Peptidyl Derivatives Based upon the Binding Site of Human Cystatin C

BACKGROUND: Antibacterial peptidyl derivative - Cystapep 1, was previously found to be active both against antibiotic-resistant staphylococci and streptococci as well as antibiotic-susceptible strains of these species. Therefore, it is a promising lead compound to search for new antimicrobial peptidomimetics.OBJECTIVES: We focused on identifying structural elements that are responsible for the bio