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Reshaping karma: an Indic metaphysical paradigm in traditional and modern astrology

The paper examines the metaphysical ideas employed to embed Hellenistic astrology in an Indian religious and cultural context, relating them to questions of causality, determinism and moral freedom. These ideas are contrasted against the largely Thesophical adaptation of the same concepts, which in the 19th and 20th centuries formed the emerging modern astrology in Europe, and which led it to aban

Building rich and grounded robot world models from sensors and knowledge resources: A conceptual spaces approach

Robots interacting with other agents in rich information landscapes and complex dynamic physical environments require sophisticated and robust concept and knowledge management capabilities if they are to solve problems, communicate, learn and exhibit intelligent behaviours. In this paper we describe how conceptual spaces provide a powerful substrate upon which to build effective concept and knowle

Investigation of turbulent combustion in humid air using a level-set flamelet library approach

To meet the demands of high electrical efficiencies in combination with low emissions for gas turbine-based power plants, wet cycles have gained new interest. The combustion chamber is a key component in such a power plant. Detailed investigations are necessary to gain insight into the formation of hazardous emissions such as CO and NOx. In this paper, computational fluid dynamics (CFD) has been e

Shape Modeling by Optimising Description Length Using Gradients and Parameterisation Invariance

In Statistical Shape Modeling, a dense correspondence between the shapes in the training set must be established. Traditionally this has been done by hand, a process that commonly requires a lot of work and is difficult, especially in 3D. In recent years there has been a lot of work on automatic construction of Shape Models. In recent papers (Davies et al., Medical Image Computing and Computer-Ass

Participative Environment Planning for the Physically Disabled Using Computer Aided Design

When planning new environments, such as homes and workplaces, for the physically disabled it is important to encourage active participation from all those involved. In a research programme initiated at the Lund Institute of Technology, Sweden, a new planning method is being introduced which utilizes computer-aided design as a planning tool. This tool supports and activates the understanding and pa

"Jag söker ett värdelöst guld/ ett guld som gör värdelöst/ guldet, allt guld!" : några ingångar till den litterära värdediskurens labryrint

This article examines the modern concept of literary value. Since the late 18th century, the problem of literary value has been regarded, from the point of view of the so called double discourse of value, as a presupposed opposition between material and spiritual ”economies”. Many Romanticist and Modernist authors believe that literature – and in a broader sense art and aesthetics – constitute a v

On Distributed Knowledge Bases for Robotized Small-Batch Assembly

The flexibility demands in manufacturing are severe, e.g., for rapid-change-over to new product variants, while robots are flexible machines that potentially can be adapted to a large variety of production tasks. Task definitions such as explicit robot programs are hardly reusable from an application point-of-view. To improve the situation, a knowledge-based approach exploiting distributed declara

Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors.

Astrocytes play a critical role during the development and the maintenance of the CNS in health and disease. Yet, their lack of accessibility from fetuses and from the brain of diseased patients has hindered our understanding of their full implication in developmental and pathogenic processes. Human pluripotent stem cells (PSCs) are an alternative source to obtain large quantities of astrocytes in

Off-design performance investigation of a low calorific gas fired two-shaft gas turbine

Gas turbine systems are predominantly designed to be fuelled with gaseous fuels within a limited Wobbe index range (typically HHV=45-55 MJ/Nm3 or 1200-1480 Btu/scf). When low calorific fuel gases are fired, the engine will be forced to operate outside its design envelope. The added mass flow will typically raise the cycle pressure ratio and in two-shaft designs also raise the gas generator shaft s

Sanning och konsekvens för svenska vattenledningar

Detta arbete kick-startar AI (artificiell intelligens) för ledningsunderhåll i VA-branschen i Sverige. Arbetet med befintliga VA-nät är idag främst reaktivt; man reparerar läckor vartefter man blir varse dem, ibland till stora kostnader om läckan är omfattande och akut. Med denna artikel vill vi sätta fokus på proaktivt arbete med ledningsnät och diskutera riskanalys inom området. En ANN-modell soThis work kick-starts AI (artificial intelligence) for pipe management among Swedish water utilities. The current work with pipe management is mainly reactive; leaks are repaired after they are detected, sometimes with large costs if the leakage is extensive and critical. With this article, we want to focus on proactive pipe network management and discuss risk analysis in the field. A previously d

Introducing Norm Creative Perspectives in Engineering and Design Educations

The design of technologies, built environments, products, or services can result in inequalities, exclusion, and discrimination, possibly because designers–often unintentionally–reproduce social norms through their designs. This strongly relates to engineering and design educations, preparing future professionals and contributing to sustainable societies. The aim of this paper is to introduce and

CRISPR editing of the PPARGC1A Gly482ser (rs8192678) polymorphism in human white adipose cells shows differential effects on mitochondrial function and adipogenesis.

Background and aims: PPARGC1A encodes PGC-1α (peroxisome proliferator-activated receptor γ coactivator 1-α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipoc

Prevalence and severity of differing dimensions of breathlessness among elderly males in the population

Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotional and affective dimensions. The aim of this research was to determine the prevalence and intensity of these dimensions of breathlessness in elderly ma