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BackgroundDiagnosing sepsis remains a challenge because of the lack of gold-standard diagnostics. Since there are no simple, broadly accepted criteria for infection, there is a risk of misclassifying sepsis patients (sepsis mimics) among patients with organ failure. The main objective of this study was to investigate the proportion of non-infected patients (sepsis mimics) in ICU patients with pres

Certainty equivalence adaptive controllers are analysed using a “data-driven Riccati equation”, corresponding to the model-free Bellman equation used in Q-learning. The equation depends quadratically on data correlation matrices. This makes it possible to derive simple sufficient conditions for stability and robustness to unmodeled dynamics in adaptive systems. The paper is concluded by short rema

DNA carries the genetic code of life, with different conformations associated with different biological functions. Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. We have deployed a host of machine learning algorithms, including the popular state-of-the-art LightGBM (a gradient boosting model), for b

This contribution analyses the evolution of public support for the single European currency, the euro, from 1990 to 2014 for a 12-country sample of the euro area (EA-12), focusing on the most recent period of the financial and sovereign debt crisis, starting in 2008. We find that citizens’ support for the euro on average was marginally reduced during the first six years of the crisis, and that sup

Den snabba utvecklingen av elektrifiering av vägtransporter i Sverige kräver forskningsbaserade beslut om placeringen av laddinfrastruktur. Europeiska unionens (EU) nya förordning för infrastruktur för alternativa bränslen (AFIR) specificerar det maximala tillåtna avståndet mellan offentliga snabbladdningsstationer (FCS) för tunga lastbilar längs det transeuropeiska transportnätverket (TEN-T). EffThe rapid progression of the electrification of road transport in Sweden requires effective research based decisions on the location of charging infrastructure. The new European Union (EU) regulation for alternative fuel infrastructure (AFIR) specifies the maximum allowed distance between public fast-charging stations (FCSs) for heavy-duty trucks along the Trans-European Transport Network (TEN-T).

Background:Serious illness conversations are an iterative, interprofessional, team-based process that includes recommendations about medical care. Yet, it is not clear how clinicians in different role groups work together in this process.Objectives:We sought to examine how interprofessional clinicians in the medical intensive care unit (MICU) who were trained in the serious illness care program (S

Purpose of review: In comatose cardiac arrest survivors, the electroencephalogram (EEG) is the most widely used test to assess the severity of hypoxic-ischemic brain injury (HIBI) and guide antiseizure treatment. However, a wide variety of EEG patterns are described in literature. Moreover, the value of postarrest seizure treatment is uncertain. Absent N20 waves of short-latency somatosensory-evok

Migratoriness in birds is evolutionary labile, with many examples of increasing or decreasing migration distances on the timescale of modern ornithology. In contrast, shifts of migration to more nearby wintering grounds seem to be a slow process. We examine the history of how Palearctic migratory landbirds have expanded their wintering ranges to include both tropical Africa and Asia, a process tha

We introduce a new database of historical Genuine Savings (GS), an indicator of sustainable development promoted by the World Bank and widely used in contemporary economic research. GS derives from the theoretical work on wealth accounting, and addresses shortcomings in conventional metrics of economic development by incorporating broader measures of saving and investment, including human capital

Background: Birds that forage while covering distance during migration should adjust traveling behaviors as the availability of foraging habitat changes. Particularly, the behavior of those species that depend on bodies of water to find food yet manage to migrate over changing landscapes may be limited by the substantial variation in feeding opportunities along the route. Methods: Using GPS tracki

Aim of the studyRates of bystander CPR are increasing, yet mortality after out-of-hospital cardiac arrest (OHCA) remains high. The aim of this survey was to explore public knowledge and attitudes to CPR. Our hypotheses were that recent CPR training (< 5 years) would be associated with a high-quality response in a case vignette of OHCA with agonal breathing, and associated with an interest to becom

Vår galax, Vintergatan, innehåller bortåt 200 miljarder stjärnor av varierande åldrar och storlekar. Under en mörk och klar natt kan man se ungefär 2000 med blotta ögat. Detta är en liten del av det stora hela, men tillräckligt för att stimulera människors nyfikenhet. Vad är de gjorda av, och varför är de där de är? Enkla frågor, som har väldigt komplexa svar. Genom att kartlägga strukturen och deContext. Large scale chemical abundance gradients in the Galactic disks, small-scale abundance structures, and the mean chemical abundance values in the Solar vicinity, are important constraints to Galactic chemo-dynamical formation and evolution models. The formation and evolution of stars, and interstellar gas and dust depends on the distribution and evolution of matter in the Galaxy. Therefore,