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Host-pathogen interactions in Streptococcus pyogenes infections, with special reference to puerperal fever and a comment on vaccine development.
Streptococcus pyogenes (group A streptococcus) causes a variety of diseases, including acute pharyngitis, impetigo, rheumatic fever and the streptococcal toxic shock syndrome. Moreover, S. pyogenes was responsible for the classical example of a nosocomial infection, the epidemics of puerperal fever (childbed fever) that caused the death of numerous women in earlier centuries. The most extensively
In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner
Dry release of suspended nanostructures
A dry release method for fabrication of suspended nanostructures is presented. The technique has been combined with an anti-stiction treatment for fabrication of nanocantilever based nanoelectromechanical systems (NEMS). The process combines a dry release method, using a supporting layer of photoresist which is removed using oxygen ashing in a reactive ion etcher (RIE), with CHF3 plasma induced de
Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence
Rod-Shaped Monocytes Patrol the Brain Vasculature and Give Rise to Perivascular Macrophages under the Influence of Proinflammatory Cytokines and Angiopoietin-2
The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth
Severe streptococcal infection is associated with M protein-induced platelet activation and thrombus formation.
Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr
Review of exergy and energy analysis of fuel cells
Recently, to reach zero emission levels, some new energy systems based on fuel cells have been developed. This paper presents a review of investigations of these systems by thermodynamics performance, mainly, energy and exergy analysis. With energy analysis, the performance of an energy conversion system cannot be effectively and accurately evaluated. But exergy analysis complements and reinforces
Demonstration of antibody‐associated cellular cytotoxicity in patients with acute myelogenous leukemia before and after chemotherapy
This study demonstrates that a cytotoxic serum reactivity not requiring the presence of complement appears in the sera of patients with acute myelogenous leukemia. The reaction is detected upon short‐term incubation of sera in vitro with autochthonous mononuclear white blood cells from peripheral venous blood of patients at the acute stage of the disease. This reactivity was demonstrated in 18/18
The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity
Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.
Previous dissertations
2025-05-28 Veronica Fransson Improvements in brain imaging using spectral computed tomography: Development and evaluation of novel techniquesLÄS MER: https://lup.lub.lu.se/record/e8978f05-343b-4fa6-abac-be14c0f347ae 2025-05-09 Minna LernerMRI-based radiotherapy of brain tumours: Implementing MRI-only radiotherapy and exploring diffusion MRI for response assessmentLÄS MER: https://lup.lub.lu.se/re
https://www.msf-malmo.lu.se/dissertations/previous-dissertations - 2025-12-11
Stockholm
Undervisningsfri Tid Vt24
230509 Undervisningsfri tid Socialhögskolan vårterminen 2024 Terminstider vt24: måndag 2024-01-15- söndag 2024-06-02 Obs! Ta i möjligaste mån hänsyn till dessa undervisningsfria tider vid schemaläggningen, så att berörda kollegor har möjlighet att närvara vid aktiviteterna. Övriga aktiviteter finns i kalendariet! Dag Datum Tid Vilka har undervisningsfri tid? Anledning Tor-fre 8-9 feb Internat Lära
https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/2023-08/Undervisningsfri%20tid%20vt24.pdf - 2025-12-10
Mast cell-associated alveolar inflammation in patients with atopic uncontrolled asthma
Background: A significant proportion of patients with asthma have persistent symptoms despite treatment with inhaled glucocorticosteroids. Objective: We hypothesized that in these patients, the alveolar parenchyma is subjected to mast cell-associated alterations. Methods: Bronchial and transbronchial biopsies from healthy controls (n = 8), patients with allergic rhinitis (n = 8), and patients with
Introduktionsmöten
Nationalekonomiska institutionen Introduktionsmöten som hålls i Nationalekonomiska institutionens regi är inte obligatoriska. Om du väljer att inte närvara på dessa möten förväntas du på egen hand inhämta den information som meddelas.Du skall själv registrera dig på dina kurser via studentportalen www.student.lu.se senast sista registreringsdag. Om du inte gör detta förlorar du din plats. Om du är
LU Holding Årsredovisning 2020
LU Holding AB 556500-1467 Box 117, SE - 221 00 Lund, Sweden, Visiting address The Spark, Medicon village, Scheeletorget 1, Lund Telephone +46 46-222 00 00 Internet www.innovation.lu.se 1 AÅ rsredovisning för LU Holding AB 556500-1467 Räkenskapsåret 2020-01-01 – 2020-12-31 Transaktion 09222115557446406774 Signerat BA, JA, SF, BN, HP, CW, CE, UR, ST, LW, ME LU Holding AB 556500-1467 Box 117, SE -
https://www.innovation.lu.se/sites/innovation.lu.se/files/2021-08/LU%20Holding%20a%CC%8Arsredovisning%202020.pdf - 2025-12-10
No title
BANGLADESH NATIONAL LAW AND POLICY REPORT CONSULTATION DRAFT 2020 Displacement in the Context of Disasters and Climate Change Funded by This report was prepared by Md Abdul Awal Khan (Independent University Bangladesh) and Matthew Scott (RWI) 2020 TABLE OF CONTENTS 1 INTRODUCTION 1 1.1. A human rights-based approach 1 2 Displacement in Numbers 3 2.1. Number of disasters and people affected in the
https://rwi.lu.se/wp-content/uploads/2024/03/Consultation-Draft_Bangladesh.pdf - 2025-12-09
PSP2015 och kursplaner 1-14
Kursplaner med litteraturlistor. De gäller från och med angiven termin och tills vidare. Engelsk översättning av kursplanerna finns antingen i menyn till höger eller längst ner på sidan. Ändring av kurslitteratur godkänns av ledningsgruppen för psykologprogrammet inför varje termin. Uppdaterade litteraturlistor finns därefter tillgängliga cirka 5 juni inför kommande hösttermin och cirka 5 december
Receptor for IgA in group A streptococci : cloning of the gene and characterization of the protein expressed in Escherichia coli
The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was
Determinants of Corruption - a Study of Zambian Ministries
Corruption is indisputably an immense obstacle for many developing countries in their endeavor to prosper economically. Zambia, a peaceful, politically stable democracy is still facing many of the problems connected with corruption. Corruption has so far mostly been measured on a state-level, but in our thesis we narrow the field of investigation down to the ministry-level. We use questionnaires t
