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Structure-property correlations of ion-containing polymers for fuel cell applications

In order to investigate the structure-property correlations of grafted proton conducting membranes, the model system consisting of an ETFE base film grafted with polystyrene and subsequent sulfonation (ETFE-g-PSSA) along with crosslinked derivatives ETFE-g-P(SSA-co-DiPB) were synthesized. The characteristics of the final membranes were characterized by PFG-NMR diffusometry, in-plane conductivity a

CSF amyloid beta 38 as a novel diagnostic marker for dementia with Lewy bodies

Background The clinical distinction between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) is sometimes difficult, particularly in mild cases. Although CSF markers such as amyloid beta 42 (A beta 42) and P-tau can distinguish between AD and normal controls, their ability to distinguish between AD and DLB is not adequate. Objective This study aims to investigate whether CSF markers, i

Lopinavir/ritonavir, atazanavir/ritonavir, and efavirenz in antiretroviral-naive HIV-1-infected individuals over 144 weeks: An open-label randomized controlled trial

Background: The objective of this study was to compare the efficacy of ritonavir boosted atazanavir versus ritonavir boosted lopinavir or efavirenz, all in combination with 2 nucleoside analogue reverse transcriptase inhibitors (NRTIs), over 144 weeks in antiretroviral-naive HIV-1-infected individuals. Methods: A prospective open-label randomized controlled trial was conducted at 29 sites in Swede

VENOUS THROMBOEMBOLISM IN SOUTHERN SWEDEN EPIDEMIOLOGY AND RISK FACTORS

Popular Abstract in Swedish Bakgrund Trots att venös blodpropp (venös tromboembolism [VTE]) är en viktig orsak till sjuklighet och dödlighet är data ofullständiga gällande dess förekomst och bakomliggande riskfaktorer hos oselekterade patienter. I begreppet VTE inkluderas blodproppar i benets djupa ådror (djup ventrombos [DVT]) och i lungorna (lungemboli [LE]). Insjuknandefrekvens i VTE varierar mDespite the fact that venous thromboembolism (VTE) is an important cause of morbidity and mortality there is still insufficient information on VTE risk factors and patient characteristics in the general population. Previously published incidences of VTE (deep venous thrombosis [DVT] and pulmonary embolism [PE]) vary from 71 to 192 per 100,000 individuals per year. Incidences of DVT and PE have bee

Prevalence of Tibiofemoral Osteoarthritis 15 Years After Nonoperative Treatment of Anterior Cruciate Ligament Injury: A Prospective Cohort Study.

BACKGROUND: The occurrence of osteoarthritis (OA), associated meniscal injuries, meniscectomy, and patient-related measures for patients treated nonoperatively after anterior cruciate ligament (ACL) injuries have not been well described in the literature in terms of natural history. HYPOTHESIS: Patients with ACL injury can achieve a low occurrence of tibiofemoral OA and good knee function when tre

Gastroesophageal Reflux after Vertical Banded Gastroplasty is Alleviated by Conversion to Gastric Bypass.

BACKGROUND: Conversion operations after vertical banded gastroplasty (VBG) are sometimes performed because of vomiting and/or acid regurgitation. Primary operation with gastric bypass (GBP) is known to reduce gastroesophageal reflux (GERD). Previous studies have not been designed to differentiate between the effects of the altered anatomy and of the ensuing weight loss. No series has reported data

Physical activity and its effect on bone in the short- and long- term perspective.

Popular Abstract in Swedish Benskörhet (osteoporos), är ett komplext, multifaktoriellt tillstånd som utvecklas i det tysta fram till den dag man drabbas av en fraktur. De senaste 40 åren har antalet benskörhetsfrakturer ökat och i dag beräknas varannan kvinna och var fjärde man någon gång drabbas av en eller flera osteoporosrelaterade frakturer. Exempel på sådana benbrott är frakturer i kota, höftOsteoporosis is a growing problem worldwide where Sweden has one of the highest fragility fracture incidences in the world. The growing years are thought to be an opportune time to build strong bones and the enhancement of peak bone mass (PBM) has been suggested as a prevention strategy for osteoporosis. Most exercise intervention studies in children, evaluating the accrual of areal bone mineral d

Both total and phosphorylated tau are increased in Alzheimer's disease

BACKROUND: Pathological tau protein concentrations in CSF are found in both Alzheimer's disease (AD) and frontotemporal dementia (FTD), but studies on brain tissue have suggested that the tau pathology in AD differs from that in FTD and that the difference may be related to the degree of phosphorylation. As CSF tau protein is increased after stroke, tau may also be implicated in the pathophysiolog

Urinary S100B protein concentrations are increased in intrauterine growth- retarded Newborns

BACKGROUND. Intrauterine growth retardation is one of the major causes of perinatal mortality and morbidity. To date, there are no reliable methods to detect brain damage in these patients. METHODS. We conducted a case-control study in tertiary NICUs from December 2001 to December 2003 with 42 intrauterine growth retardation infants and 84 controls. Routine laboratory variables, neurologic outcome

Quantification of cystatin C by time-resolved fluorometry-based immunoassays

Plasma cystatin C is increasingly used as a marker of glomerular filtration rate. Most assays for cystatin C are based on turbidimetric or nephelometric detection and studies of other rapid methods are limited. This study aimed to develop and compare differently configured immunoassays for quantification of plasma cystatin C, using recombinant cystatin C and two cystatin C-specific antibodies. Met

Prognostic sub-classifications of T1 cutaneous melanomas based on ulceration, tumour thickness and Clark's level of invasion. Results of a population-based study from the Swedish Melanoma Register.

Background: Survival and prognostic factors for thin melanomas have been relatively little studied in population-based settings. This patient group account for the majority of melanomas diagnosed in western countries today and better prognostic information is needed. Objective: The aim of this study is to use established prognostic factors such as ulceration, tumour thickness and Clark's level of

Sexual orientation and self-rated health: the role of social capital, offence, threat of violence, and violence.

Objective: To study the association between sexual orientation and self-rated health, including trust, offence, threat of violence, and violence. Design/setting/participants/measurement: The 2008 Public Health Survey in Skåne is a cross-sectional postal questionnaire study. A total of 28,198 persons aged 18-80 years responded (55%). Logistic regressions analysed the association between sexual orie

No association of COMT val158met polymorphism and psychotic symptoms in Lewy body dementias

We sought to determine whether the COMT val158met polymorphism (rs4680) is associated with delusions and hallucinations in people with dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). A total of 218 individuals, recruited from centres in Norway, Sweden and the UK were included in this study; 121 with clinically or neuropathologically diagnosed DLB/PDD and 97 age-matched, cog

Comparison of contrast-to-noise ratios of transmission and dark-field signal in grating-based X-ray imaging for healthy murine lung tissue

Purpose: An experimental comparison of the contrast-to-noise ratio (CNR) between transmission and dark-field signals in grating-based X-ray imaging for ex-vivo murine lung tissue. Materials and Methods: Lungs from three healthy mice were imaged ex vivo using a laser-driven compact synchrotron X-ray source. Background noise of transmission and dark-field signal was quantified by measuring the stand

Alterations of the fragile histidine triad gene, FHIT, and its encoded products contribute to testicular germ cell tumorigenesis

The fragile histidine triad (FHIT) gene, located within chromosome arm 3p, is a potential target for testicular tumorigenesis. In the present study, 62 primary testicular germ cell tumors were analyzed for allelic imbalance (AI) at 10 loci mapping to chromosome bands 3p14.1-21.1. Twenty-seven tumors (44%) showed AI at one or more 3p loci. The chromosome 3 copy number was evaluated by fluorescence

Combustion of Chemical Substances and the Impact on the Environment of the Fire Products: 1/3 Scale Room Furnace Experiments

This report describes the results obtained from fire tests in a 1/3-scale room. The aim of the study was to investigate how changes in external radiation and oxygen supply affect the production of smoke and toxic gases. The ventilation was varied to simulate under- and well-ventilated fires. The thermal exposure to the materials was varied to simulate fires of different sizes. Fifty-nine tests wer

Child related background factors affecting compliance with induction of anaesthesia

BACKGROUND: Factors such as age, sex, behaviour problems, fears, earlier traumatic hospital events and reactions to vaccination were assessed together with behaviour observed before premedication in order to evaluate their importance in predicting response to the anaesthetic process. The anaesthetic process was divided into four endpoints; compliance when given premedication, sedation, compliance

Further insight in the web consolidation process - Part III. Modelling of paper shrinkage

A model for the web consolidation process in the paper dryer is developed and compared with experimental data for the kraft pulps. The model contains one parameter called the shrinkage factor which is used as the fitting parameter to the experimental data. The shrinkage factor can have a value between zero implying no shrinkage and a value of one which implies that all the liquid volume removed le

Treatment outcome in T-cell lymphoblastic lymphoma in adults - a population-based study from the Swedish Lymphoma Registry

Background. T-cell lymphoblastic lymphoma (T-LBL) is a rare neoplasm of precursor lymphoblast origin, for which there is no standard treatment for adults. Results of current treatment strategies in selected populations do exist but are largely unreported for unselected series. Here, we aimed to investigate treatment outcome in a population-based cohort. Material and methods. Patients were identifi

Discarding Heparins as Treatment for Progressive Stroke in Sweden 2001 to 2008

Background and Purpose-High-dose heparin has been used extensively to treat patients with progressive ischemic stroke, but the scientific support is poor and the current stroke guidelines advise against its use. We studied how heparin treatment for progressive stroke has been discarded in Sweden. Methods-All 78 hospitals in Sweden that admit acute stroke patients participate in Riks-Stroke, the Sw