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The glutamic acid decarboxylase 65 immunoglobulin G subclass profile differs between adult-onset type 1 diabetes and latent autoimmune diabetes in adults (LADA) up to 3 years after clinical onset.

Autoantibodies against glutamic acid decarboxylase 65 (GADA) are found frequently in patients with autoimmune diabetes. Immunoglobulin (Ig)G(1) is the most frequent subclass among the GADA IgG subclasses. IgG(4) is a more common subclass in latent autoimmune diabetes in adults (LADA) at clinical onset compared to type 1 diabetes. The aim of this work was to study the different GADA-IgG subclass pr

Eit-food-systems-factsheet-2025

EIT Food Systems EIT MSc in Food Systems LUND UNIVERSITY | SWEDEN • Master of Science in Food Systems • 2 years, full-time, 120 ECTS credits • Faculty of Engineering and EIT Food • Semester 1 and 4 – Lund Campus, semester 2 and 3 at EIT Food partner universities according to track • Application deadline: www.mfs-apply.eitfood.eu/ Programme start: August 2025 PROGRAMME OVERVIEW The Master’s program

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2024-08/Eit-food-systems-factsheet-2025.pdf - 2026-05-06

Morphological and electromyographical studies of trapezius myalgia in cleaners

Popular Abstract in Swedish Sammanfattning på svenska Avhandlingen är en sammanläggningsavhandling, bestående av fem delarbeten. I avhandlingen studeras yrkesrelaterad muskelvärk (myalgi) i kappmuskeln (trapezius) ur framförallt morfologiska, histopatologiska och elektromyografiska aspekter hos en förhållande stor grupp av försökspersoner. Försökspersonerna består av städerskor med och utan yrkesrPathomechanisms of work-related myalgia are poorly understood. Myalgia is caused by exitation of nociceptors present in the muscular tissue but not in the muscle fibres themselves. Morphological analysis can contribute to knowledge of excitation of nociceptors. Surface EMG is a widely used method in the research field of ergonomics. Knowledge of influence of myalgia, occupation, age and intrinsic

The 14-3-3 protein family - Conserved structure, diverse functions

While once abstruse, 14-3-3 proteins are now well known as players in several cellular processes. These processes range from apoptosis and mitosis in mammals and yeast, to regulation of primary metabolism in plants. To date, 104 proteins have been shown to interact with 14-3-3s of which 85 are found in mammals and yeast, and 21 are found in plants. Their consensus action is to bind to phosphorylat

Early intraperitoneal metabolic changes and protease activation as indicators of pancreatic fistula after pancreaticoduodenectomy

Background: Ischaemia and local protease activation close to the pancreaticojejunal anastomosis (PJA) are potential mechanisms of postoperative pancreatic fistula (POPF) formation. To provide information on the pathophysiology of POPF, intraperitoneal microdialysis was used to monitor metabolic changes and protease activation close to the PJA after pancreaticoduodenectomy (PD). Methods: In patient

Bile duct obstruction is associated with early postoperative upregulation of liver uncoupling protein-2 and reduced circulating glucose concentration in the rat

Objective: To evaluate whether upregulation of liver and muscle uncoupling protein 2 (UCP-2) is an acute phenomenon in obstructive jaundice and associated with secondary metabolic effects. Methods: Male Sprague-Dawley rats were divided into four groups bile duct ligated (BDL) and sham-operated pair-fed (PF), ad libitum fed (AL), and controls BDL. PF. and AL rats were further divided into subgroups

Microstructure and water distribution of commercial pasta studied by microscopy and 3D magnetic resonance imaging

Manufacturing pasta is a rather well known process, but it is still challenging to tailor pasta products with new raw materials. In this study, we evaluated the effects of raw materials on the microstructure and water distribution in cooked pasta using H-1 magnetic resonance imaging (MRI) as well as bright field and polarized light microscopy. The MRI parameters initial intensity (I-0) and transve

Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

Recent genome-wide association studies (GWASs) conducted in Asian populations have identified novel risk loci for systemic lupus erythematosus (SLE). Here, we genotyped 10 single-nucleotide polymorphisms (SNPs) in eight such loci and investigated their disease associations in three independent Caucasian SLE case-control cohorts recruited from Sweden, Finland and the United States. The disease asso

Adding formoterol to budesonide in moderate asthma--health economic results from the FACET study

The FACET (Formoterol and Corticosteroid Establishing Therapy) study established that there is a clear clinical benefit in adding formoterol to budesonide therapy in patients who have persistent symptoms of asthma despite treatment with low to moderate doses of an inhaled corticosteroid. We combined the clinical results from the FACET study with an expert survey on average resource use in connecti

Modifying a standard method allows simultaneous extraction of RNA and protein, enabling detection of enzymes in the rat retina with low expressions and protein levels

The aim of the study was to evaluate messenger RNA and protein expression in limited amounts of tissue with low protein content. The Chomczynski method was used for simultaneous extraction of RNA, and protein was modified in the protein isolation step. Template mass and cycling time for the complementary DNA synthesis step of real-time reverse transcription-polymerase chain reaction (RT-PCR) for a

Adverse drug reaction reporting by nurses in Sweden

Aim To investigate whether nurses could be a useful tool for improving the reporting rate of adverse drug reactions (ADRs). Furthermore, we wanted to study how physicians working at the study departments would respond to nurses as reporters of ADRs and if the reporting from the nurses affected the reporting rate from the physicians. Methods Three departments of internal medicine and one unit for o

Akupunkturbehandling vid spädbarnskolik - föräldrars upplevelser av barnets beteende före och efter behandling

Infantile colic is causing pain and trouble to infants and their parents. Acupuncture is used to relieve the symptoms but is not scientifically tested as treatment for infantile colic. In this study the experiences of parents, whose 68 babies have got acupuncture, were investigated. The way the parents described their babies behaviour and feeding patterns was analysed with content analysis at a ma

Single-Dose Antibiotic Prophylaxis in Core Prostate Biopsy: Impact of Timing and Identification of Risk Factors.

objectives: To assess the level of infectious complications and the impact of timing of a single, prophylactic, oral dose of ciprofloxacin 750 mg given either 2 hours before or in conjunction with ultrasound -guided core biopsy of the prostate in men without recognised risk factors and to analyse potential risk factors. Methods: All men undergoing prostate biopsy for elevated prostate specific ant

Minority cytotypes in European populations of the Gymnadenia conopsea complex (Orchidaceae) greatly increase intraspecific and intrapopulation diversity

Patterns of ploidy variation among and within populations can provide valuable insights into the evolutionary mechanisms shaping the dynamics of plant systems showing ploidy diversity. Whereas data on majority ploidies are, by definition, often sufficiently extensive, much less is known about the incidence and evolutionary role of minority cytotypes. Ploidy and proportions of endoreplicated genome

Effects of lime and ash treatments on ectomycorrhizal infection of Pinus sylvestris L. Seedlings planted in a pine forest

Plots in a 40-yr-old Scots pine (Pinus sylvestris) stand in S. Sweden were treated with 5 tons tonnes? lime/ha, 7.5 tons wood-ash/ha, or left untreated. One-yr-old P. sylvestris seedlings were planted in each of the plots in early June, 12 months after ash treatment and 18 months after lime treatment. The pH of the limed, ash treated and untreated plots were 5.2, 6.4 and 3.8, respectively. Four mo

Impact of an 84-hour workweek on biomarkers for stress, metabolic processes and diurnal rhythm

Objectives This study examined the degree to which long workhours in combination with an extended workweek (12 hours/7 days) with permanent day shifts (0700-1900), as requested by the workers, influenced biomarkers for stress, metabolic processes, and diurnal rhythm. Methods Construction workers (N=50) working 84 hours a week, with alternate weeks off, were compared with construction workers (N=25

Gene expression profiling of Escherichia coli expressing double Vitreoscilla haemoglobin

In a recent investigation, expression of a double Vitreoscilla haemoglobin (two fused VHb molecules) in Escherichia coli grown in shake flasks resulted in higher final cell density and considerably higher levels of ribosomes and tRNA. In this study, we have investigated the E. coli transcriptome in cells expressing native VHb, double VHb and control cells lacking VHb by hybridising mRNA from the d

Multifocal electroretinography (mfERG) in insulin dependent diabetics with and without clinically apparent retinopathy

Purpose: To Study the retinal function, using multifocal electroretinography (mfERG), in diabetic patients with mild and moderate retinopathy, and in diabetics without clinically apparent retinopathy. Methods: Thirty-one patients with insulin dependent diabetes mellitus, eleven without any clinically apparent retinopathy, twelve with mild retinopathy and eight with moderate retinopathy, were studi