Search results

Popular Abstract in Swedish Att balansera. Cancer från ett primärvårdsperspektiv. Diagnostik, posttraumatisk stress och vård vid livets slut Denna avhandling belyser cancer från en utgångspunkt som kanske inte handlar om vad man först kommer att tänka på när man hör ordet cancerforskning. Det handlar inte om att “lösa cancerns gåta” eller att hitta nya metoder för behandling eller diagnos. UtgångThis thesis explores cancer from a primary care perspective covering three areas: diagnosis, posttraumatic stress disorder (PTSD), and end-of-life care. We analyzed patient records of every child diagnosed with a malignancy in a defined area. During 12 years 68 children were diagnosed (incidence 14/100,000). For 68% the diagnosis was initiated in primary care. There were 25 children with leukemia

Presents an iterative approach to optimal control when modeling errors are present. The problem considered is movement of open containers containing liquid in an industrial packaging machine. The goal is to move as fast as possible without too much slosh. There is no measurement of the slosh available in the machine, therefore open loop control via the acceleration reference is the only possibilit

Popular Abstract in Swedish För att en multicellulär organism som männinskan ska kunna fungera måste celldelningen strikt kontrolleras. Protein som reglerar celldelning på cellulär nivå kallas för "tillväxtfaktorer". Vi har studerat ett sådant protein som kallas för transforming growth factor-beta (TGF-b). Namnet TGF-b kommer sig utav att detta protein kan transformera (omvandla) epiteliala njurceTransforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. The costimulatory effect depends on the presence of monocytes and is mediated by these cells. Furthermor

Popular Abstract in Swedish ”Vi kommo överens om att möten innehålla alla livets möjligheter, och att en människa som levat mycket vet mycket om möten om hon alls vet någonting.” Så uttalar den kvinnliga huvudpersonen i Mannen vid min sida (1933) sin övertygelse efter mötet med älskaren. Denna avhandling fokuserar mötet i Elin Wägners trettiotalsromaner. Genom att analysera detta vill avhandlingsfThe aim of this present thesis is to present the Utopian scheme in Elin Wägner’s novels of the nineteen-thirties: Dialogen fortsätter (1932) (“The Dialogue Continues”), Mannen vid min sida (1933) (“The Man by my Side”), Genomskådad (1937) (“Unmasked”) and Hemlighetsfull (1938) (“Mysterious”). With her authorship Wägner was aiming for a new social order, a radical change, polväxling (a shift of pol

In this work, we propose a computationally efficient time-updating algorithm for estimating the spectral content of a signal with missing samples. The algorithm extends earlier work on the topic by formulating a data-interpolation scheme reducing the required complexity to a fraction of the earlier efficient implementation, without resulting in any noticeable loss of performance for even a quite l

An important regulatory suppressive function in autoimmune and other inflammatory processes has been ascribed to CD4(+) Foxp3(+) regulatory T cells (Tregs), which requires direct cell-cell communication between Tregs, effector T cells, and APCs. However, the molecular basis for these interactions has not yet been clarified. We show here that sialoadhesin (Sn), the prototype of the siglec family of

In this work, the binding kinetics of amino acid-based surfactants, presenting different linkers and head groups, with calf thymus (CT)-DNA was studied using stopped-flow fluorescence spectroscopy. The kinetic studies were carried out as a function of Na+ concentration and surfactant-to-DNA charge ratio. The surfactant binding on DNA took place in two consecutive steps, for which the corresponding

Plant biologists have long recognized that host defence against parasites and pathogens can be divided into two conceptually different components: the ability to limit parasite burden (resistance) and the ability to limit the harm caused by a given burden (tolerance). Together these two components determine how well a host is protected against the effects of parasitism. This distinction is useful

The fact that men and women are living longer than they have ever done before is something in which we can all rejoice. However, the process of ageing is associated with changes in skeletal, muscular, gastrointestinal, neural hormonal and metabolic processes that seriously affect an individual's performance and quality of life. Indeed, Such changes can be contributory to a loss of independence in

Many species in the animal kingdom are characterized by alternative mating tactics (AMTs) within a sex. In males, such tactics include mate guarding versus sneaking behaviours, or territorial versus female mimicry. Although AMTs can occur in either sex, they have been most commonly described in males. This sex bias may, in part, reflect the increased opportunity for sexual selection that typically

This article uses conceptual metaphor theory to develop the concept of ‘skeumorphs’ (reuse of old concepts for new phenomena) in order to analyse the Swedish The Pirate Bay court case. In line with conceptual metaphor theory, which states that abstract thinking is largely metaphorical, the article argues that this is true also for digital phenomena that, thus, are largely understood through metaph