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Comparison of the image rejection between the passive and the Gilbert mixer

This paper presents a comparison of the image rejection between Gilbert mixer and the passive mixer. A simple model for mixers is set up, and the image rejection performance of passive and Gilbert mixer is analyzed based on it. Simulations and calculations were done to compare the image rejection of the two mixers. The results show that the Gilbert mixer, comparing with the passive one, shows a st

Modelling multi-scale deformation of amorphous glassy polymers with experimentally motivated evolution of the microstructure

Novel experimental data, obtained recently using advanced multi-scale experiments, have been used to develop a micro-mechanically motivated constitutive model for amorphous glassy polymers. Taking advantage of the experiments, the model makes use of a microstructural deformation gradient to incorporate the experimentally obtained deformation of the microstructure, as well as its evolving orientati

Cryogenic hydrogen cooling of heated moderator vessel

In ESS, a pulsed proton beam of 5 MW mean power will hit a tungsten target to generate neutrons by spallation. The pulses are 2.86 ms long and occur with 14 Hz; the power within a pulse is 125 MW. Only centimeters from the target, the neutrons are moderated by liquid hydrogen in aluminium vessels. The deposited power heats the surrounding structures and fluids which are circulated and cooled. The

Lateral Protein-Protein Interactions at Hydrophobic and Charged Surfaces as a Function of pH and Salt Concentration

Surface adsorption of Thermomyces lanuginosus lipase (TLL) - a widely used industrial biocatalyst - is studied experimentally and theoretically at different pH and salt concentrations. The maximum achievable surface coverage on a hydrophobic surface occurs around the protein isoelectric point and adsorption is reduced when either increasing or decreasing pH, indicating that electrostatic protein-p

Identification of a strongly activating human anti-CD40 antibody that suppresses HIV-1 infection

We characterized the functional properties of a novel set of human anti-CD40 monoclonal antibodies originating from a human phage display library and identified an antibody that strongly activates cells via the CD40 receptor for potential use in HIV therapy. The anti-CD40 antibodies were converted from a single chain antibody fragment format (scFv) to an IgG format and produced in HEK293 cells, an

The experiences of older people living with cancer

Nursing care for older people with cancer requires an understanding of their history and current needs from both an individual and generalized view. The aim of this study was to investigate the experience of older people living with cancer and the way it affects their daily life. During the study, 41 individuals 75 years of age and older (mean age, 83 years) who had a cancer diagnosed within the p

Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands.

BACKGROUND. Hypoxia induces increased tumor growth by promoting angiogenic and glycolytic pathways. Tumors expressing hypoxia-inducible factor-la (HIF-1 alpha), an important transcriptional activator of oxygen-regulated genes, are resistant to chemotherapy and radiotherapy. The major challenge in prostate cancer therapy today is to gain a better understanding of the development of hormone-refracto

A preliminary analysis of the groundwater recharge to the Karoo formations, mid-Zambezi basin, Zimbabwe

A multi-disciplinary study is being carried out on recharge to the Karoo sandstone aquifer in the western part of Zimbabwe, where recharge is controlled by the presence of a thick, confining basalt layer. The aquifer is geographically extensive, and has been identified throughout the southern part of the mid-Zambezi basin (Fig. 1). The potential for groundwater abstraction seems to be huge. The ke

Amniotic fluid S100B protein in mid-gestation and intrauterine fetal death

Fetal death in the mid-trimester of pregnancy is unexplained and no reliable markers are available to identify at-risk women. We aimed to assess use of a fetoprotein and S100B concentrations in amniotic fluid as markers. We did a case-control study in 758 healthy women undergoing amniocentesis at mid-gestation, of whom 12 had a spontaneous intrauterine fetal death before 28 weeks, and 746 matched

WASTE PICKERS MOBILISE AGAINST INCINERATOR IN SÃO BERNARDO DO CAMPO : São Paulo, Brazil

The municipal government of São Bernardo do Campo, São Paulo, proposed the construction of the Usina Verde incinerator for urban solid waste in 2012 through a public-private partnership with SBC Valorização de Resíduos Revita e Lara. The plant would burn 3,000 tonnes of waste daily and produce energy. Located in the Alvarenga neighbourhood, the former landfill area, it would replace recycling and