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What does it take to make a customer return? René van Pelt and Ida de Wit Sandström are retail workers in the specialist jewellery trade. They have been serving their customers together for more than fifteen years. In a world where digitalisation is changing the business conditions, demands regarding distinction and profiling are increasing and consumers are becoming ever more unpredictable , show
We introduce the concept of “residual investigation” for program analysis. A residual investigation is a dynamic check installed as a result of running a static analysis that reports a possible program error. The purpose is to observe conditions that indicate whether the statically predicted program fault is likely to be realizable and relevant. The key feature of a residual investigation is that
Bacteria have evolved diverse immunity mechanisms to protect themselves against the constant onslaught of bacteriophages1-3. Similar to how eukaryotic innate immune systems sense foreign invaders through pathogen-associated molecular patterns4 (PAMPs), many bacterial immune systems that respond to bacteriophage infection require phage-specific triggers to be activated. However, the identities of s
BACKGROUND: Cancer-associated fibroblasts (CAFs) are molecularly heterogeneous mesenchymal cells that interact with malignant cells and immune cells and confer both anti- and pro-tumorigenic functions. Prior in situ profiling studies of human CAFs have largely relied on scoring single markers, thus presenting a very limited view of their molecular complexity. Our objective was to study the complex
What happens when global market-oriented models for auditing and quality assessment are taken up by local parishes? The paper is based on case studies where a number of parishes and auditing models provide the object of study. Parishes are to some extent restrictive about embracing new ideas on auditing and quality control. With assistance from neo-institutional theory it can be shown that the co
The complete rotational CARS (coherent anti-Stokes Raman scattering) spectrum of ethane (C2H6) has for the first time been recorded instantaneously under high spectral resolution, and the potential for thermometry has been investigated. Experiments were performed in the temperature range 292-650K in pure ethane and in binary mixtures with nitrogen. A polarization technique was used to suppress the
Numerical simulation of numerous mm/cm-sized particles embedded in a gaseous disk has become an important tool in the study of planet formation and in understanding the dust distribution in observed protoplanetary disks. However, the mutual drag force between the gas and the particles can become so stiff - particularly because of small particles and/or strong local solid concentration - that an ex
Ballistic imaging is the name applied to a category of optical techniques that were originally developed for medical applications. Recently, ballistic imaging was adapted to acquire instantaneous images of the liquid core inside atomizing sprays; a region that has been heretofore inaccessible to spray researchers. An important difference between spray research and the medical imaging problem is th
This paper examines the profound impact of digital technology on Classical and Mediterranean archaeology, with a focus on digital field recording and infrastructure. Using the 'skeuomorphism of practice' framework, it traces the integration of technology into our current practice. The Swedish Pompeii project is used as a case study to illustrate the adoption of 3D models into traditional archaeolo
BACKGROUND AND AIMS: Systolic blood pressure (SBP) drops recorded by 24-hour ambulatory blood pressure (BP) monitoring (ABPM) identify patients with susceptibility to reflex syncope and orthostatic intolerance. We tested the hypothesis that treatments aimed to increase BP (reassurance, education & life-style measures plus pharmacological strategies) can reduce SBP drops.METHODS: Multicentre, o
To investigate multimodal signals in cat–human communication we recorded 36 cat–owner interactions in everyday situations that were judged by the owners for valence (negative, mixed or positive). We then coded the videos for behaviour using an ethogram including vocal, visual and tactile (multimodal) signals. Vocalisations were segmented and acoustic measures of duration and F0 obtained. In cats,
Receptors, transporters, and ion channels are important targets for therapy development in neurological diseases, but their mechanistic role in pathogenesis is often poorly understood. Gene editing and in vivo imaging approaches will help to identify the molecular and functional role of these targets and the consequence of their regional dysfunction on the whole-brain level. We combine CRISPR-Cas9
This chapter examines the complex relationship between social enterprises and taxation. The focus is not on a specific country, although various examples are mentioned. As specific tax measures for social enterprises are a form of tax incentives, the chapter discusses this public finance concept. In addition, an important legal constraint on introducing such incentives for social enterprises in th
HAMLET (human α-lactalbumin made lethal to tumor cells) is a protein-lipid complex that induces apoptosis-like death in tumor cells, but leaves fully differentiated cells unaffected. This review summarizes the information on the in vivo effects of HAMLET in patients and tumor models, on the tumor cell biology, and on the molecular characteristics of the complex. HAMLET limits the progression of hu
