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Exposure to ambient air pollution during pregnancy has been associated with an increased risk of preeclampsia (PE). Some suggested mechanisms behind this association are changes in placental DNA methylation and gene expression. The objective of this study was to identify how early pregnancy exposure to ambient nitrogen oxides (NOx) among PE cases and normotensive controls influence DNA methylation

Background and purpose — There is an ongoing debate regarding the appropriate level of constraint in primary TKA. To provide increased stability and better kinematics, more resembling a natural knee, a medial congruent (MC) tibial insert has been introduced. To investigate potential impact on implant migration, we evaluated the cemented Persona TKA, randomizing between MC and cruciate-retaining (C

In order to develop new environmental policies, it is important first to evaluate those that have already been used. However, this intuitively simple idea is difficult to apply in practice, no more so than in the complex governance context of the EU. Attributing impacts to specific policies is challenging, and making evaluations useful for political decision making is even more demanding. Five app

Austrian artist and director of ZKM Center for Art and Media in Karlsruhe, Germany, Peter Weibel (Odessa, 1944), curates a book/catalogue of the mythical exhibition Sound Art, Sound as Medium of Art, that took place between March 2012 and February 2013 in Karlsruhe, with nearly one thousand images of sound art pieces. Along with a very detailed historical trace of sound as a form of art, the book

This chapter presents life cycle assessment (LCA) and its current and potential use as a tool of governance. LCA is considered as providing governance input in three different dimensions: (1) as results; (2) as a method; and (3) as a mindset. Life cycle approaches are increasingly informing policymaking and legislation, either as an abstract idea such as “the circular economy” or as calculation ru

In 2024 the European Declaration of Cycling was signed as a tri-institutional declaration by the European Commission, Council of the European Union and the European Parliament. For the first time, cycling was acknowledged as a fully fledged mode of transport in a EU-level framework and through it, cycling now sits officially on the agenda of the EU. Yet this level of political attention was for ma

In this introductory chapter we chart colonial aspirations and projects of early modern Scandinavian kingdoms and discuss political and economic thinking that fuelled and justified these projects. We situate Danish and Swedish colonial venture, ideology and economic concerns that stood behind the global expansion in the context of contemporary European thinking and politics.

Background: Fluid resuscitation after uncontrolled hemorrhage might promote rebleeding and irreversible shock. Tranexamic acid is a procoagulant drug that limits blood loss after surgery of the hip, knee, and heart. We hypothesized that pretreatment with tranexamic acid reduces the rebleeding in uncontrolled hemorrhage and thereby allows safe administration of crystalloid fluid resuscitation.Metho

In this afterword, Marie Cronqvist, Fredrik Mohammadi Norén, and Emil Stjernholm tie together the chapters in Media Tactics in the Long Twentieth Century and summarise some of the book's key themes. Three key knowledge contributions are highlighted. First, the volume foregrounds tactics as a study object in itself, not just the effects or outcomes of strategic thinking. Second, the book counters t

Qualitative and quantitative visualizations of transonic turbomachinery flows provide essential information on compressibility and Mach number effects on boundary layer development, shock-boundary layer interactions (SBLI) and trailing edge flows. Background Oriented Schlieren (BOS) is a relatively new optical technique that allows capturing unsteady density gradient fields through turbomachinery

It is increasingly important to rapidly receive information on the antimicrobial susceptibility of bacteria due to the rise in antimicrobial resistance worldwide. However, traditional phenotypic methods are time-consuming. Thus, the objective of this study was to develop a rapid assay that can detect antibiotic-resistant bacterial isolates phenotypically in less than 2 h. The microplate assay used

This chapter explores the concept of “activist learning for sustainability” and the role of activism and related pedagogies and the relationship to education for sustainable development (ESD). The chapter will reflect on a case study of student-led activism: the initiation of a “sustainable student house” devised and developed by students to allow them to “live what they are learning” and educate

Social media platforms open up new methods of candidate messaging, voter contact, and data acquisition. Currently, affordances is a popular concept used to study the relationship between political campaigns and how they use social media platforms. Scholars argue that since platforms have different designs, they offer different affordances that affect how campaigns use social media. This chapter ev

Marginal zone B cells (MZB cells) are innate like B cells that are predominantly located alongside memory B cells in the microanatomical region of the spleen of humans and mice termed the marginal zone. They circulate in humans but not mice, and in humans can be identified in blood and other lymphoid tissues, including the gut-associated lymphoid tissue, where they, as in spleen, form a zone surro