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Background: Cortical contusions are common in moderate-severe traumatic brain injury (TBI). Cortical contusions often expand, potentially causing neuro-worsening several hours to days post-trauma. While contusion expansion (CE) may affect outcome, potential clinical and radiological markers that can predict CE have been insufficiently explored. In the present single-center retrospective observatio

Traditionally, traffic safety is expressed through the number of accidents (crashes) or people injured, since these are the most direct manifestations of an unsafe traffic environment. As we discuss in this chapter, such an approach has its limitations due to the low frequency of accidents and some other issues. Neither is it unusual that accident data is not available, not reliable or lacks impor

This essay examines the philosophical questions posed in Virginia Woolf’s famous novel Mrs Dalloway (1925) set in London in the aftermath of World War I. In her unique tone and poetic aesthetics, Woolf deals with questions about war and its aftermaths, evil and oppressive power, time and temporality, duality of life, fear of suffering and death, sacrifice and suicide but also, most importantly, lo

I denna rapport föreslås en metod som syftar till att fördjupa förståelsen för identifiering av verifieringsbehovet, som rekommenderas i de svenska byggreglerna för analytisk dimensionering av byggnadstekniskt brandskydd. Syftet med denna rapport är att ge vägledning åt ingenjörer att noggrant ta reda på vilken effekt en förändring av en byggnads utformning har på byggnadens brandskyddssystem. FöIn this report a method is proposed that aims to deepen the understanding for identification of the need for verification that is recommended in Swedish regulations for performance based design of fire safety in buildings. The purpose of this report is to provide guidance to engineers on how to thoroughly identify the effect that an alteration to a building design has on the buildings total fire s

Tasquinimod (a quinoline-3-carboxyamide) is a small molecule immunotherapy with demonstrated effects on the tumor microenvironment (TME) involving immunomodulation, anti-angiogenesis and inhibition of metastasis. A target molecule of tasquinimod is the inflammatory protein S100A9 which has been shown to affect the accumulation and function of suppressive myeloid cell subsets in tumors. Given the m

According to medieval canon law, a marriage could be declared invalid if the consent had been given through force or fear. This ruling was a natural consequence of the insistence on free consent as the only requirement for a valid marriage. It did, however, entail a number of both practical and theoretical problems. It could be difficult to prove force and fear within the family, but also to defin

Popular Abstract in Swedish Jordens dotter. Selma Lagerlöf och den tyska hembygdslitteraturen. Avhandlingen undersöker mottagandet av Selma Lagerlöfs verk i Tyskland åren runt sekelskiftet 1900. Selma Lagerlöf introducerades på den tyska bokmarknaden 1896 med en översättning av debutverket Gösta Berlings saga. Redan tidigt under sin litterära karriär uppmärksammades hon i tysk press och nådde på This dissertation studies the reception of the works of the Swedish author Selma Lagerlöf in Germany at the turn of the century 1900. Selma Lagerlöf was introduced into the German book market in 1896, with a translation of her first novel, “The Saga of Gosta Berling”. She was well received by the German press and had after only a couple of years managed to get herself an impressive readership, whi

It is tempting to assume that Information Systems Development Methodology (ISDM) is clearly understood because it has attracted researchers across a range of research fields offering a rich set of descriptions and explanations of ISDM. Although there are considerable studies on ISDM, this paper argues that different disciplinary interests have resulted in fragmented assessments. Consequently, this

On a software development project many people collaborate to build a product contributing different pieces of the final product. Often people on a development team will work in parallel, either on different parts or on the same parts of the product, and follow processes to co-ordinate their work with other people on the team. When teams are distributed this co-ordination becomes more difficult sin

Natural food webs are embedded in a variable environment, which causes population densities to fluctuate, despite a potential stable equilibrium. Population interactions as well as the characteristics of the environmental fluctuations determine the resulting population dynamics. Populations sensitive to the same kind of environmental disturbances will show correlated responses in their respective

HAMLET, a complex of α-lactalbumin and oleic acid, preferentially kills cancer cells and is also effective in vivo. HAMLET causes apoptosis but cells die even if this pathway is inhibited. Thus, the role of autophagy, an alternative cell death pathway, was examined. During autophagy double membrane-enclosed autophagosomes form around cellular material and deliver it to the lysosomes for degradatio

Controlled vocabularies (CVs), i.e. a collection of predefined terms describing a modeling domain, used for the semantic annotation of data, and ontologies are used in structured data formats and databases to avoid inconsistencies in annotation, to have a unique (and preferably short) accession number and to give researchers and computer algorithms the possibility for more expressive semantic anno

Popular Abstract in Swedish Våra celler är täckta av kolhydrater (socker) som är kopplade till proteiner och lipider på cellens yta. Olika celler presenterar olika socker, och en och samma cell kan dessutom ändra sitt sockeruttryck beroende på hur den mår och vad den vill utföra, till exempel dela sig eller dö, en effekt man ofta ser i cancer. På så sätt fungerar sockerstrukturerna som en kod som There is an intensive interest in characterising the structure and function of galectins, which is not surprising given their many important cellular functions and strong implications in human disease. Understanding the mechanisms involved in galectin functions will help to find selective and novel strategies for disease treatment and diagnosis. A key to this lies in their carbohydrate binding spe

Are voiceless approximants categorically distinct from voiceless fricatives? We address this question by means of acoustic analysis of voiceless laterals in Icelandic, Welsh, and the endangered variety Estonian Swedish. All three have a voiceless lateral functioning in contrast to a voiced lateral approximant. The analysis focused on duration – including any period of voicing (‘pre-voicing’) just

The recent progress in our work to implement salt (NaCl) as a dosemeter is presented. Laboratory investigations have indicated a linear dose response from 1 mGy to about 100 mGy and detection limits down to 0.1 mGy. Investigations in the clinic comparing TL-dosimetry in LiF and OSL in NaCl have indicated a similar dose response for the two dosemeters at different photon energies. Field studies wit

The infrared spectrum of water, isolated in inert matrices, has been studied in the interval from 60 to 4000 cm(-1). Experiments with partially deuterated water combined with DFT (density functional theory) calculations have been used to investigate the structure of matrix-isolated water tetramer. A few, strong intermolecular fundamentals of the water tetramer have been observed. Mid-infrared band