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Randomised controlled trials have shown that screening may significantly reduce mortality in coloretcal cancer. In the present evaluation it is shown that the reported reduction of 15 per cent, or higher, is given in relative figures. With absolute figures the reduction is only 0.15 per cent or lower. The number of individuals needed to invite for screening (NNT) biannually for 10 years to prevent

Background: The postantibiotic effect (PAE) of meropenem and ciprofloxacin was studied in the presence of the antineoplastic agent 5-fluorouracil (5-FU). The purpose of the study was to investigate whether the PAEs of the combinations differed from the PAEs of the antibiotics alone. Methods: The PAEs of the combinations of 5-FU plus meropenem or ciprofloxacin were determined with viable counts aga

This paper presents architectures for supporting dynamic data scaling in pipeline fast Fourier transforms (FFTs), suitable when implementing large size FFTs in applications such as digital video broadcasting and digital holographic imaging. In a pipeline FFT, data is continuously streaming and must, hence, be scaled without stalling the dataflow. We propose a hybrid floating-point scheme with tail

In this paper, we break new ground by presenting algorithms for fixed-rate compression of high dynamic range textures at low bit rates. First, the S3TC low dynamic range texture compression scheme is extended in order to enable compression of HDR data. Second, we introduce a novel robust algorithm that offers superior image quality. Our algorithm can be efficiently implemented in hardware, and sup

The incidence of pancreatic cancer has fallen during the last ten years in Sweden. Early signs and symptoms of the disease are still undiscovered and when diagnosis is made the disease is incurable in most patients. Transabdominal ultrasonography is the first-line imaging test followed by spiral computed tomography (CT) and magnetic resonance imaging (MRI) if required for definite diagnosis. Spira

OBJECTIVE: To determine the prevalence of type 2 diabetes and impaired fasting glycemia (IFG) in a rural population of Bangladesh. RESEARCH DESIGN AND METHODS: A cluster sampling of 4,923 subjects >/=20 years old in a rural community were investigated. Fasting plasma glucose, blood pressure, height, weight, and girth of waist and hip were measured. BMI and waist-to-hip ratio (WHR) were calculated.

The overall aims of this thesis were to investigate the prevalence, severity and bother of Lower Urinary Tract Symptoms (LUTS) in a clinical sample of stroke patients and to evaluate the effect of pelvic floor muscle training (PFMT) in women with urinary incontinence after ischemic stroke. The thesis consisted of 6 articles based on 4 studies and a review. In the first study (Paper I), the Danish

The aim of our survey was to capture the attitudes of Swedes to marginal donors and xenotransplantation. Modern biotechnology makes it possible to replace non-functioning organs, cells, and genes. Nonetheless, people may have reservations and fears about such treatments. With the survey, Attitudes of the General Public to Transplants, we have sought to expose the ambivalence that arises when medic

Endoglin is a transforming growth factor-beta (TGF-beta) accessory receptor recently identified as being highly expressed on long-term repopulating hematopoietic stem cells (HSC) However, little is known regarding its function in these cells. We have used two complementary approaches toward understanding endoglin's role in HSC biology: one that efficiently knocks down expression via lentiviral-dri

The motion of paraxial atomic beams in a laser radiation field is studied within the framework of a parabolic equation. Exact analytical solutions of the parabolic equation are found for a variety of potentials featuring a nonuniformity in the propagation direction. Special attention is paid to the propagation of cold atomic beams in the gradient field of the TEM01* laser radiation mode. Explicit

Lifetimes of a superdeformed band in Sr-82 were measured with the centroid shift method. The measured average quadrupole moment of this band corresponds to a quadrupole deformation of beta(2) approximate to 0.49, which is slightly smaller than both the theoretical prediction, and the measured deformation of the SD band in the neighboring isotone Zr-84. Lifetimes of high spin states of three normal

In seeking to advance the understanding of the production, diffusion and negotiation of meaning in and between organisations, we introduce below the notion of mise-en-sens. Mise-en-sens refers to the performing art term of mise-en-sce` ne and builds on the French term sens denoting meaning as well as direction. Starting from a qualitative analysis of how Swedish wind farm developers manage the per

We assessed all patients who underwent tissue expansion, excluding breast reconstructions, between 1984 and 1999. A total of 237 patients had 257 expansions, normally for distorted scars, 202 of 257 cases (79%). Their mean age was 27 (range 7- 67) years, most being women, 149 of 237 (63%). The mean duration of expansion was 16 weeks (range 0.4-118). The most common site was the skull (61/257). Pro

First results are reported from a major new initiative of experiments, which focus on nuclear structure studies at extreme isospin values by means of isomer spectroscopy. The experiments represent the first part of the so-called stopped-beam campaign within the Rare ISotope INvestigations at GSI (RISING) project. Time-correlated gamma decays from individually identified nuclear species have been m

Background Although much is known about the reactivity of polyclonal populations of antibodies targeting the wide array of allergens produced by timothy (Phleum pratense) and other grass species, little is known about the finer details at the level of individual antibody specificities. Objective We sought to investigate the IgE repertoire as it occurs in a patient with grass pollen allergy. Meth

Background The purpose of these studies was to compare efficacy and toxicity of docetaxel alone with the combination of gemcitabine and docetaxel for treatment of metastatic esophageal carcinoma. Patients and methods These studies enrolled patients with histopathologically verified squamous cell carcinoma or adenocarcinoma of the esophagus or cardia. Between March 1997 and June 1999, 52 patients w