Immune activation is a regular feature of sepsis, but the incidence and nature of the ensuing inflammation-resolving and immunosuppressive component is less well understood. In this study, we compared immunoregulatory markers on blood leukocytes from patients with Gram-negative or Gram-positive sepsis or septic shock, and compared this to blood from patients with severe virosis or healthy controls

A micromechanically motivated model is proposed to capture nonlinear effects and switching phenomena present in ferroelectric polycrystalline materials. The changing remnant state of the ferroelectric crystal is accounted for by means of so-called back fields-such as back stresses-to resist or assist further switching processes in the crystal depending on the local loading history. To model interg

In this contribution we study the balloon angioplasty in a residually stressed artery by means of a non-local gradient-enhanced fibre damage model. The balloon angioplasty is a common surgical intervention used to extend or reopen narrowed blood vessels in order to restore the continuous blood flow in, for instance, atherosclerotic arteries. Inelastic, i.e. predominantly damage-related and elastop

Entrained flow gasification of biomass using the cyclone principle has been proposed in combination with a gas engine as a method for combined heat and power production in small to medium scale (99.9% of the particulate matter smaller than 1 lm.

The current research focuses on creating a homogeneous charge compression ignition (HCCI) fuel index suitable for comparing different fuels for HCCI operation. One way to characterize a fuel is to use the auto-ignition temperature (AIT). The AIT can be extracted from the pressure trace. Another potentially interesting parameter is the amount of low temperature heat release (LTHR) that is closely c

Knee osteotomy is a joint preserving surgery with new techniques and implants introduced during recent years. However the information of its use and outcome is scarce. A national knee osteotomy register was started in Sweden in 2013 from which we report here the information gathered during the first year of registration.

Four randomized studies show that adjuvant radiotherapy (RT) lowers the risk of subsequent ipsilateral breast events (IBEs) after breast-conserving surgery (BCS) for ductal carcinoma in situ (DCIS) by approximately 50% after 10 to 15 years. We present 20 years of follow-up data for the SweDCIS trial.

Background: Social and lifestyle influences on age-related changes in body morphology are complex because lifestyle and physiological response to social stress can affect body fat differently. Objective: We examined the associations of socioeconomic status (SES) and lifestyle factors with body mass index (BMI) and waist circumference (WC) in middle-aged and elderly European men. Design and setting

Except for the scattered cephalopod conchs that have given the rock type its name, mollusk fossils are relatively rare in the Middle Ordovician 'orthoceratite limestone' of Sweden. However, an interval in the Darnwilian stands out as being unusually rich in various types of mollusks. Throughout southern Sweden, gastropods became relatively abundant close to the Volkhov-Kunda Baltoscandian Stage bo

The HIV-1 capsid protein, p24 antigen, is of considerable diagnostic interest because following HIV exposure it is detectable several days earlier than host-generated HIV antibodies (which are the target of almost all current tests used in the field) and can be used to design very sensitive assays without the need for PCR. Here, we present an ultrasensitive capacitive immunosensor that is capable

This study investigates the retention of different sized ultra-small superparamagnetic iron oxide nanoparticles (USPIOs) in lymph nodes of healthy rats, after subcutaneous injection. Three distinct sizes (15, 27 and 58 nm) of USPIOs were synthesized by only varying the thickness of the polymer coating surrounding the 10 nm cores. Particles were injected on the dorsal side of the hind paw of rats a

The use of light emitting diodes (LEDs) in outdoor lighting has energy-saving potential, but users' responses to this light source are largely unknown. An intervention study in two residential areas compared conventional lighting installations (high pressure sodium in Area 1 and high pressure mercury in Area 2) to a retrofitted LED-alternative regarding residents' perceptions of quality of light,

Abstract is missing (Short Communication).

Some observational evidence-such as bimodal drop size distributions, comparatively high concentrations of supercooled drops at upper levels, high concentrations of small ice crystals in cloud anvils leading to high optical depth, and lightning in the eyewalls of hurricanes-indicates that the traditional view of the microphysics of deep tropical maritime clouds requires, possibly, some revisions. I

The purpose was to estimate the proportion of current open aortic arch reconstructions that might be feasible for endovascular repair. From all elective repair made in Southern Sweden in one center between 2005 and 2012, 129 open and eight endovascular aortic arch repairs were identified. The anatomy of the ascending arch and descending aorta as well as the arch vessels was categorized from multip

A crucial requirement in the development of liquid-metal spallation neutron target is knowledge of the composition and amount of volatile radionuclides that are released from the target during operation. It is also important to know the total amount produced, which could be released if there was an accident. One type is the lead-bismuth eutectic (LBE) target where different radionuclides can be pr

Synthetic molecular motors typically take nanometer-scale steps through rectification of thermal motion. Here we propose Inchworm, a DNA-based motor that employs a pronounced power stroke to take micrometer-scale steps on a time scale of seconds, and we design, fabricate, and analyze the nanofluidic device needed to operate the motor. Inchworm is a kbp-long, double-stranded DNA confined inside a n

An acute meal study was performed to determine postprandial glucose and insulin responses after consumption of two fermented oat bran-based beverages (with and without exopolysaccharides) and yoghurt. This randomized, single-blind, within-subject study included 18 healthy, overweight participants. Four breakfast meals, including a reference meal, were tested; all meals contained 50 g of available

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated ∼2,000, ∼3,700 and ∼9,500 SNPs explained ∼21%, ∼24% and ∼29% of phenotypic variance. Furthermore, all common variants